Could a nerve zap and talk therapy soothe your upset stomach?

NCT ID NCT06360900

Recruiting now Symptom relief Sponsor: Spaulding Rehabilitation Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 16, 2026 · Updated 5 times

Summary

This study tests whether combining a nerve-stimulating device (placed on the ear) with behavioral therapy can reduce stomach pain and anxiety in people with functional dyspepsia, a condition where the stomach feels upset without a clear cause. Researchers will track symptoms and stomach movement using MRI. The trial involves 80 adults who will attend weekly therapy sessions online and use the device daily at home.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: vagal nerve stimulation device and behavioral therapy
What this could lead to: If it works, this could offer a new drug-free way to manage functional dyspepsia symptoms and related anxiety.
What could go wrong: This is an early-stage study with only 80 people, so results may not apply to everyone. The device and therapy may not provide significant relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dyspepsia functional gastric disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FUNCTIONAL DYSPEPSIA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02129, United States

Contact Email: •••••@•••••

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