Brain artery stent coated with drug may cut stroke risk better than pills alone
NCT ID NCT04948749
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This trial compares two strategies to prevent another stroke in people with severe narrowing of a major brain artery. One group receives a drug-eluting stent (a mesh tube that releases medication to keep the artery open) along with aggressive blood-thinning medication. The other group gets medication alone. The study tracks who has a stroke, dies, or experiences serious bleeding within one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a drug-eluting stent (Maurora Sirolimus-Eluting Stent) plus aggressive medical treatment (dual antiplatelet therapy with aspirin and clopidogrel)
- What this could lead to
- If successful, this approach could offer a more effective way to prevent repeat strokes in people with hardened brain arteries, potentially reducing disability and death.
- What could go wrong
- This is a mid-sized trial, and stenting carries risks like bleeding or vessel damage. The results may not apply to all patients or artery locations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
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Locations
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Baotou Central Hospital
RECRUITINGBaotou, Inner Mongolia, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Daxing District People's Hospital
RECRUITINGBeijing, Beijing Municipality, China
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Beijing Tiantan Hospital
RECRUITINGBeijing, Beijing Municipality, 100070, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beilun People's Hospital of Ningbo City
RECRUITINGNingbo, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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General Hospital of Benxi Iron and Steel Co
RECRUITINGBenxi, Liaoning, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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General Hospital of The Yangtze River Shipping
RECRUITINGWuhan, Hubei, China
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Hejian People's Hospital
RECRUITINGCangzhou, Hebei, China
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Inner Mongolia Autonomous Region People's Hospital
RECRUITINGHohhot, Inner Mongolia, China
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Lishui People's Hospital
RECRUITINGLishui, Zhejiang, China
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North China University of Science and Technology Affiliated Hospital
RECRUITINGTangshan, Hebei, China
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Shanxi Cardiovascular Hospital
RECRUITINGTaiyuan, Shanxi, China
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Shanxi Provincial People's Hospital
RECRUITINGTaiyuan, Shanxi, China
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The First Affiliated Hospital of College of Medicine
RECRUITINGHangzhou, Zhejiang, China
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The Second Affiliated Hospital of Nanjing Medical University
RECRUITINGNanjing, Jiangsu, China
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The Second Norman Bethune Hospital of JilinUniversity,
RECRUITINGChangchun, Jilin, China
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Tongliao City Hospital
RECRUITINGTongliao, Inner Mongolia, China
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Wuhai People's Hospital
RECRUITINGWuhai, Inner Mongolia, China
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Xingtai City Third Hospital
RECRUITINGXingtai, Hebei, China
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