Which ablation method best prevents stroke in atrial fibrillation?

NCT ID NCT06253000

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two common procedures—radiofrequency and cryoablation—for treating persistent atrial fibrillation, a heart rhythm disorder that raises stroke risk. Researchers will track 158 adults over 24 months to see which method better prevents strokes, transient ischemic attacks, and death. The goal is to identify the safest and most effective approach for long-term control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cryoablation and radiofrequency ablation procedures

What this could lead to

If successful, this could help doctors choose the best ablation method to reduce stroke and recurrence in patients with persistent atrial fibrillation.

What could go wrong

This is a single-center study with 158 participants, so results may not apply to all patients. Both procedures carry risks like bleeding or heart damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Atrial Remodeling Death persistent atrial fibrillation stroke disorder transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bakulev National Medical Research Center for Cardiovascular Surgery

    RECRUITING

    Moscow, 121552, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••