New study tests weight loss and exercise combo for stroke recovery

NCT ID NCT05901675

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether a structured weight loss program, with or without added exercise, can improve physical function and emotional well-being in obese veterans who have had a stroke. Researchers will enroll 130 participants aged 35-85 who had a stroke at least 6 months ago. The program uses meal replacements and dietitian support, plus exercise for some groups, to see if it helps with walking and daily life.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Lifestyle management program (dietary meal replacements and structured diet) with or without exercise
What this could lead to
If successful, this could show that combining weight loss with exercise helps stroke survivors walk better and feel better emotionally.
What could go wrong
This is a relatively small, early-stage study without a control group for the exercise component, so results may not apply to all stroke survivors. Weight loss programs can be hard to stick with long-term.

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Conditions

The condition(s) this trial relates to.

Motor Activity Obesity obesity disorder stroke disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • College of Health Professions

    RECRUITING

    Charleston, South Carolina, 29425, United States

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