Could a 'Mirror' brain stimulation trick help stroke and amputee patients?

NCT ID NCT05766059

Recruiting now Symptom relief Sponsor: Istituto Auxologico Italiano Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new non-invasive brain stimulation technique called mirror-PAS, which combines visual and motor signals to promote brain plasticity. Researchers will compare it to standard brain stimulation in 36 people with stroke-related arm weakness or phantom limb pain. The goal is to see which method better improves movement and reduces pain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transcranial Magnetic Stimulation (TMS) with paired associative stimulation
What this could lead to: If it works, this could point toward a new non-invasive treatment to help stroke survivors regain movement and reduce phantom limb pain.
What could go wrong: This is a very early, small study (36 people) testing only short-term effects. The approach may not lead to lasting improvement or work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEMIPARESIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hemiplegia Paresis Phantom Limb stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMIPARESIS PHANTOM LIMB PAIN STROKE

Contacts and locations

Locations

Istituto Auxologico Italiano IRCCS
RECRUITING

Milan, Lombardy, 20122, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.