Could a 'Mirror' brain stimulation trick help stroke and amputee patients?
NCT ID NCT05766059
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a new non-invasive brain stimulation technique called mirror-PAS, which combines visual and motor signals to promote brain plasticity. Researchers will compare it to standard brain stimulation in 36 people with stroke-related arm weakness or phantom limb pain. The goal is to see which method better improves movement and reduces pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcranial Magnetic Stimulation (TMS) with paired associative stimulation
What this could lead to
If it works, this could point toward a new non-invasive treatment to help stroke survivors regain movement and reduce phantom limb pain.
What could go wrong
This is a very early, small study (36 people) testing only short-term effects. The approach may not lead to lasting improvement or work for everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Istituto Auxologico Italiano IRCCS
RECRUITINGMilan, Lombardy, 20122, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••