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Blood thinner warfarin under scrutiny for dialysis patients with irregular heartbeat

NCT ID NCT03862859

Recruiting now Disease control Sponsor: Nicholas Carlson Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the blood thinner warfarin can safely reduce stroke risk in people with end-stage kidney disease on dialysis who also have atrial fibrillation (an irregular heartbeat). About 718 adults will be randomly assigned to take warfarin or not, and researchers will track strokes and major bleeding over time. The goal is to find out if the benefits outweigh the risks in this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Warfarin (a blood thinner)
What this could lead to
If it works, this could clarify whether warfarin is safe and effective for preventing strokes in dialysis patients with atrial fibrillation.
What could go wrong
This is a Phase 4 trial, but results may not apply to all patients. Warfarin carries a known risk of major bleeding, especially in dialysis patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation chronic kidney disease end stage renal failure stroke disorder ischemic stroke prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION AND FLUTTER END-STAGE RENAL DISEASE MAJOR BLEED STROKE

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aalborg University Hosptial

    RECRUITING

    Aalborg, 9100, Denmark

    Contact Email: •••••@•••••

  • Aarhus University Hospital

    RECRUITING

    Aarhus, 8200, Denmark

    Contact Email: •••••@•••••

  • Bornholms Hospital

    RECRUITING

    Rønne, 3700, Denmark

    Contact Email: •••••@•••••

  • Department of Nephrology, Copenhagen University Hospital Rigshospitalet

    RECRUITING

    Copenhagen, 2100, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Department of Nephrology, Herlev Hospital

    RECRUITING

    Herlev, Herlev, 2730, Denmark

    Contact Email: •••••@•••••

    Contact

  • Department of nephrology, Nordsjaellands Hospital

    RECRUITING

    Hillerød, Hillerød, 3400, Denmark

    Contact Email: •••••@•••••

    Contact

  • Esbjerg and Grindsted Hospital

    RECRUITING

    Esbjerg, 6700, Denmark

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Holbaek Hospital

    RECRUITING

    Holbæk, 4300, Denmark

    Contact Email: •••••@•••••

  • Holstebro Hospital

    RECRUITING

    Holstebro, 7500, Denmark

    Contact Email: •••••@•••••

  • Hospital Sønderjylland

    RECRUITING

    Sønderborg, 6400, Denmark

    Contact Email: •••••@•••••

  • Lillebælt Hospital

    RECRUITING

    Kolding, Denmark

    Contact Email: •••••@•••••

  • Viborg Regional Hospital

    RECRUITING

    Viborg, 8800, Denmark

    Contact Email: •••••@•••••

  • Zealand University Hospital

    RECRUITING

    Roskilde, 4000, Denmark

    Contact

    Contact Email: •••••@•••••

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