STROKE

This study tests whether starting a special exercise program soon after a stroke can protect the brain from memory loss and dementia. Researchers will enroll 120 people who had a stroke in the past 6 months. Participants will do a mix of exercises, and the study will measure chan…

This study tests a new virtual reality (VR) walking therapy for people who have had a stroke within the past 1 to 6 months. Participants will use either a fully immersive VR system that lets them walk over ground in realistic environments, or a semi-immersive VR system on a tread…

This study tests a new device called CLAAS that is placed in the heart to prevent strokes in people with atrial fibrillation (an irregular heartbeat). About 1600 participants will be randomly assigned to get either the new device or one of two already-approved devices. The goal i…

This study tests a structured problem-solving approach called CO-OP (Cognitive Orientation to daily Occupational Performance) for adults who have had a stroke or traumatic brain injury. Participants learn a 'Goal-Plan-Do-Check' strategy to tackle everyday tasks like dressing or c…

This study tests whether the drug clevidipine can lower blood pressure quickly and steadily in people having a bleeding stroke (intracerebral hemorrhage). High blood pressure can make the bleeding worse, so getting it under control fast is critical. The trial will compare clevidi…

This study is testing whether stem cells taken from a person's own bone marrow and then given back through the veins and nose can improve brain and nerve function. It includes 500 people with various conditions like stroke, Parkinson's, Alzheimer's, and nerve damage. The goal is …

This study looks at whether adding a blood thinner to standard antiplatelet therapy helps prevent strokes and blood clots in people who develop a new, temporary irregular heartbeat after coronary artery bypass surgery. About 3,200 adults who had bypass surgery and then experience…

This study tests whether adding GM1, a natural brain substance, to standard clot-removal treatment helps people recover better after a severe stroke. About 868 adults in China who have a blocked artery in the front part of the brain will receive either GM1 or a placebo daily for …

This study compares a new 'virtual stroke unit' approach to standard stroke unit care for people with a stroke who are not eligible for a clot removal procedure. The virtual unit uses video calls and monitoring equipment to let a specialist team at a main hospital help guide care…

This study compares two blood thinner strategies after left atrial appendage closure (LAAC) in people with atrial fibrillation. Sixty participants will receive either aspirin alone or aspirin plus clopidogrel for three months. The goal is to see which approach better prevents sma…

This study tests whether the Luna EMG rehabilitation robot can help people who had a stroke more than a year ago improve arm movement. Five participants will use the robot for 30 minutes per session as part of their rehab. The goal is to see if the robot can make arm movements sm…

This study tests whether infliximab (Remicade), a drug used for arthritis and other inflammatory conditions, can shrink a specific type of brain aneurysm called a dolichoectactic vertebrobasilar (DVB) aneurysm. These aneurysms are difficult to treat with surgery or stents, and th…

This study tests whether implanting small filters in the carotid arteries (the main neck arteries) can prevent repeat strokes in people with atrial fibrillation who have already had a stroke. Participants will receive the filters plus standard blood thinners, or blood thinners al…

This early study tests a device that reads brain signals and stimulates the spinal cord to help people with chronic stroke move their arms and legs again. Only 3 participants will be implanted with electrodes on the brain and spine. The main goal is to check safety, but researche…

This study compares two treatment strategies for elderly frail patients with atrial fibrillation (AF) who are at high risk for both stroke and bleeding. One group receives catheter ablation plus a device to close the left atrial appendage (LAAO), while the other receives ablation…

This study tests a nurse-led program called BEST CARE ICTUS_HC for adults hospitalized with acute stroke in hospitals without specialized stroke units. The program includes staff training, swallowing tests, and environmental adaptations to help with attention and safety. Research…

This study looks at people over 65 who recently had a stroke with no clear cause. Doctors suspect they may have hidden atrial fibrillation (an irregular heartbeat) not caught in the hospital. The trial compares two treatments: a blood thinner (apixaban) or aspirin, to see which b…

This study compares two exercise programs—sensorimotor training and dual-task training—against standard physical therapy for stroke survivors. The goal is to see which approach best improves balance, mobility, and reduces fall risk. Fifty-four participants who had a stroke at lea…

This study compares two treatments for small ischemic strokes (lacunar strokes): a combination of antiplatelet drugs (pills) versus the standard clot-busting drug tPA given through an IV. The goal is to see if the pill combo works just as well but causes fewer bleeding problems. …

This study tests whether adding mental imagery training to robotic hand exercises improves arm and hand function in people who had a stroke at least 6 months ago. Forty participants will receive either robotic hand training alone or combined with mental imagery over 7 weeks. The …

This study tests a new device that uses brain signals to time magnetic pulses for stroke rehabilitation. The device reads blood flow changes in the brain and fires a magnetic pulse at the right moment to boost brain activity. Researchers will first test the system in healthy adul…

This study tests whether a robotic hand device can help people recovering from a stroke improve hand strength and dexterity better than standard physical therapy. Thirty adults with sub-acute stroke (2 weeks to 6 months post-stroke) will be randomly assigned to receive either rob…

This study tests whether Diroximel Fumarate, a drug already used for multiple sclerosis, can reduce harmful brain swelling that often occurs after a hemorrhagic stroke. The swelling, called perihematomal edema, can worsen recovery. The trial will enroll 192 adults who have had a …

This study tests whether robot-assisted foot and ankle training, combined with virtual reality, can help people with chronic stroke walk faster and improve balance. Thirty participants will either receive this robotic therapy or standard manual training, plus usual rehab, for 6 w…

This study tests whether combining a brain-computer interface training with audio cues played during sleep can improve arm function in people who had a stroke at least 6 months ago. 70 participants will practice moving a cursor on a screen using muscle signals, then hear related …

This study tests whether a structured care bundle—including rapid blood pressure control, reversal of blood thinners, and management of fever and blood sugar—can improve outcomes for people with a brain bleed. About 3500 adults in Sweden and Australia will receive either the care…

This study tests a tool called Savvy, which includes phone exercises, a weekly pill organizer, and text reminders, to help stroke survivors take their blood pressure medication as prescribed. Researchers will compare medication adherence and blood pressure control between those u…

This study looks at whether the blood thinner warfarin can safely reduce stroke risk in people with end-stage kidney disease on dialysis who also have atrial fibrillation (an irregular heartbeat). About 718 adults will be randomly assigned to take warfarin or not, and researchers…

This study looks at whether a 15-week lifestyle program combining weight management and exercise can improve walking and daily function in obese veterans who had a stroke at least six months ago. Researchers will measure changes in walking distance, daily steps, and overall recov…

This study is testing whether a device that uses mild electrical pulses to stimulate arm muscles and the tongue can help stroke survivors regain arm movement. Researchers will enroll 288 participants, including stroke patients with arm weakness and healthy controls. The main goal…

This study tests a new decision-making tool called IMPROVE that uses MRI scans to detect unstable plaques in the carotid artery. The goal is to see if this method is at least as good as the current standard (which mainly looks at how narrow the artery is) for selecting which pati…

This study tests whether a mild brain stimulation technique called tDCS, combined with treadmill training, can improve walking in people who have had a stroke. Researchers will enroll 100 adults who are at least 3 months past their first stroke and have trouble walking. The goal …

This study compares two common procedures—radiofrequency and cryoablation—for treating persistent atrial fibrillation, a heart rhythm disorder that raises stroke risk. Researchers will track 158 adults over 24 months to see which method better prevents strokes, transient ischemic…

This study tests a device called GORE® CARDIOFORM Septal Occluder to close a small hole in the heart (PFO) in people who have had a stroke with no clear cause. About 636 participants will get the device plus blood-thinning medicine. The goal is to see if this reduces the chance o…

This study tests a drug called DM199 in about 728 people who have had a moderate stroke and cannot get clot-removing treatments. The drug is given through a vein and then as shots under the skin for three weeks. Researchers want to see if it helps patients recover better than a p…

This study tests whether a smart glove can help people with brain disorders (like stroke or brain injury) improve arm and hand function from home. Forty adults with lasting arm weakness will either use the smart glove for guided exercises or do standard home therapy. The goal is …

This international study tests whether a robotic exoskeleton (Gloreha Sinfonia) combined with standard therapy can improve arm function in people who recently had a stroke. 130 participants will be randomly assigned to either robotic therapy plus standard care or standard care al…

This study is testing whether giving a clot-busting drug (tenecteplase) directly into the blocked brain artery can improve outcomes for people having a stroke caused by a medium-sized vessel blockage. About 282 participants will be randomly assigned to receive either the intra-ar…

This study looks at whether removing a large blood clot from the brain (endovascular thrombectomy) is better than standard medical care for stroke patients who already had a moderate-to-severe disability before their stroke. About 1,060 adults with a recent stroke and a pre-exist…

This early study tests a brain-computer implant that reads brain signals to help people with severe paralysis (from ALS, stroke, or spinal cord injury) communicate. The device aims to decode imagined speech and allow control of computers. Only 2 participants will be enrolled to c…

This study tests whether using remote-controlled CT scans at local medical centers, guided by a hospital stroke team via video call, can speed up treatment for stroke patients. About 52 participants with suspected stroke will be randomly assigned to either this new approach or st…

This study looks at whether a structured weight loss program, with or without added exercise, can improve physical function and emotional well-being in obese veterans who have had a stroke. Researchers will enroll 130 participants aged 35-85 who had a stroke at least 6 months ago…

This pilot study is testing whether a noninvasive device that sends mild electrical pulses through the skin to the spinal cord can help improve arm and hand function in people with stroke or spinal cord injury. Researchers will measure changes in nerve activity and movement skill…

This study tests whether a team of community health workers, social workers, and nurses can help stroke survivors who face social challenges like food or housing insecurity. The team visits participants at home starting within 72 hours of hospital discharge, offering referrals, c…

This study tests a 6-month nurse-led rehabilitation program for stroke patients in Bangladesh. The program includes education booklets and assistive devices to help with daily activities. 166 participants will be randomly assigned to either the rehab program or usual care. The go…

This study tests whether the clot-busting drug tenecteplase can help people who have had a stroke 24 to 72 hours earlier. Currently, such drugs are only given within a few hours. The trial will compare tenecteplase to standard care (blood thinners) in 330 adults with blocked brai…

This study tests whether combining two non-invasive therapies can improve hand function in people who had a stroke at least six months ago and have severe arm weakness. The therapies are a brain stimulation technique called rTMS and a device that uses electrical stimulation to op…

This study tests whether freezing specific nerves (cryoneurolysis) can reduce shoulder pain and improve movement in people with spasticity from conditions like stroke or brain injury. Fifty adults will either receive one session of nerve freezing or one session of Botox injection…

This study tests whether adding the antibiotic minocycline to standard stroke care can improve survival and reduce disability in adults who have had a moderate stroke. About 1,164 participants will be randomly assigned to receive either minocycline pills for five days plus usual …

This study tests whether adding multisensory virtual reality to treadmill training helps stroke patients improve their leg movement and thinking skills. Forty adults who had a first stroke and can walk with minor help will be randomly assigned to either VR-enhanced treadmill trai…

This study tests whether a high-dose, high-intensity neurorehabilitation program using digital devices (MindMotion GO, Izar) is feasible for stroke patients. 120 adults with stroke will train about one hour per day, five days a week, across inpatient and home settings. The goal i…

This study tests a new device called SSMD to help people with arm weakness after a stroke or traumatic brain injury. About 150 adults will use the device in supervised sessions over 5-6 weeks. The goal is to see if it improves arm movement better than standard electrical stimulat…

This study tests two programs for people recovering from a stroke who are leaving inpatient rehab to go home. Half of the 520 participants will get a standard stroke education program, while the other half will get a program that helps modify their home environment. The goal is t…

This study tests whether combining a gentle brain stimulation technique (tDCS) with exercises that challenge both thinking and walking can improve how stroke survivors handle doing two things at once. Seventy-two participants who had a stroke at least six months ago will receive …

This study looks at whether a cardiac rehabilitation program can improve recovery for people who have had a stroke. Researchers will enroll 150 stroke survivors and add cardiac rehab to their usual care. They will measure walking ability, daily function, and whether the program r…

This study compares robot-assisted tai chi training to standard physical therapy for improving arm function in people who have had a stroke. 120 participants will do 60-minute sessions, five days a week for four weeks. Researchers will measure motor recovery using standard tests …

This study tests a pharmacy-led program for low-income patients with multiple chronic conditions like diabetes, heart disease, and depression. After leaving the hospital, participants get their medications with no copay, delivery to their bedside and home, and help from a pharmac…

This program gives children with brain disorders like cerebral palsy or stroke access to umbilical cord blood infusions. The treatment uses donated cord blood cells to help repair brain damage. Kids up to age 26 with normal immune function may qualify. The goal is to improve symp…

This study tests a weight-loss program delivered via telehealth for people who have had a stroke. The goal is to help participants lose weight and improve their health, especially those in underserved communities. The study will compare the program to a wait-list control group an…

This study tests whether giving a strong cholesterol-lowering drug (PCSK9 inhibitor) before emergency stroke treatment helps people recover better. About 652 adults with a major stroke will be randomly assigned to receive either the intensive drug or standard care. The main goal …

This study tests whether bringing blood pressure down very quickly (below 120 mmHg) after a stroke clot removal procedure improves recovery. About 910 stroke patients will be randomly assigned to either intensive or standard blood pressure management. The goal is to see if this a…

This study tests whether deep brain stimulation (DBS) combined with physical therapy can improve arm weakness in people who had a stroke 1 to 6 years ago. About 202 participants will receive either DBS plus rehab or rehab alone. The goal is to see if the treatment safely restores…

This study tests a new way to manage blood pressure in people having a stroke who receive clot-busting medication. The goal is to see if adjusting blood pressure treatment can lower the risk of bleeding in the brain. About 340 participants will be randomly assigned to either the …

This study tests whether blood thinners (NOACs) can prevent stroke in people who develop atrial fibrillation only during stressful events like surgery or serious illness. About 2,270 participants will be randomly assigned to take a blood thinner or not, and researchers will track…

This study is testing whether a home-based ankle robot, with or without functional electrical stimulation (FES), can improve leg movement and walking in people who have had a stroke. The trial will include 60 participants who are at least 6 months post-stroke and can walk a short…

This study compares two treatments for stroke patients whose brain arteries remain blocked after initial clot removal, due to underlying hardening of the arteries (atherosclerosis). About 498 participants will be randomly assigned to receive either urgent stenting or continued st…

This study tests whether using a balloon guide catheter during mechanical thrombectomy (a procedure to remove blood clots) can improve blood flow restoration in a single attempt for people with acute ischemic stroke caused by internal carotid artery blockage. About 364 participan…

Neuralink is testing a brain-computer interface called the N1 Implant, placed by a robot, to help people with severe paralysis communicate. The study will enroll 6 adults with conditions like ALS or spinal cord injury who cannot speak or use their hands well. The main goal is to …

This trial tests a new, less invasive surgery to remove blood clots from the brain after a severe stroke caused by bleeding. The surgery is done within 8 hours of symptoms starting. About 240 adults with large brain bleeds will be randomly assigned to either this surgery or stand…

This study is testing a culturally modified version of the Group Lifestyle Balance program for Hispanic/Latino people who have had a stroke. The program focuses on healthy eating and physical activity to help participants lose weight and reduce their risk of type 2 diabetes. Rese…

This study tests whether using augmented reality (AR) or virtual reality (VR) during treadmill walking can improve balance and walking in people who have had a stroke. 66 participants will be split into three groups: one using VR, one using AR, and a control group doing home exer…

This study looks at whether an over-the-counter supplement called MitoQ and a technique called ischemic conditioning (using a blood pressure cuff to briefly restrict blood flow) can improve blood vessel function in people who have had a stroke. About 30 stroke survivors will take…

This study compares two ways to help stroke survivors control their blood pressure: home monitoring alone versus home monitoring plus group medical visits. High blood pressure is the leading cause of a second stroke, so the goal is to find a better method to keep blood pressure i…

This study tests whether a surgically implanted device that sends mild electrical pulses to the spinal cord can improve arm and hand movement in people who have paralysis on one side after a stroke. Twenty participants aged 20 to 70 will receive the implant along with physical th…

This study compares two treatments for arm spasticity (stiff, tight muscles) caused by stroke, spinal cord injury, or brain injury. Thirty adults will first receive Botox injections, then undergo tendon-lengthening surgery a few months later. Researchers will measure how well eac…

This study tests whether a nurse-led health education program for first-time stroke patients and their family caregivers can lower the chance of having another stroke. The program includes face-to-face sessions, phone reminders, and tools like a blood pressure machine and salt sp…

This study tests whether taking spirulina (a microalgae) or seaweed (Gelidium corneum) supplements for 20 weeks can improve markers of heart health and change gut bacteria in people at high risk for heart disease. The trial includes 150 adults aged 50 or older with conditions lik…

This study compares video-based nurse consultations to standard in-person visits for people who recently had a stroke. About 196 participants will be randomly assigned to either telecare or face-to-face follow-up. The goal is to see if remote care can maintain or improve disabili…

This Phase 3 trial tests whether the drug Dimephosphon can improve recovery in people who have had an acute ischemic stroke. About 184 adults aged 35-80 will receive either Dimephosphon or a placebo within 24-72 hours of their stroke. The main goal is to see if more patients achi…

This study tests whether a non-invasive treatment called remote ischemic conditioning (RIC) can help people recover after surgery for a ruptured brain aneurysm. RIC involves using a blood pressure cuff on the leg to create brief, harmless blood flow interruptions, which may trigg…

This phase 3 trial is testing whether two drugs—colchicine (used for gout) and ticagrelor (a blood thinner)—can prevent future strokes, heart attacks, and other vascular events in people who have already had a stroke. About 2,800 high-risk participants will be enrolled. The goal …

This study tests a wearable robotic glove that reads brain signals to help people who have had a stroke move their hand and arm. Sixty participants will be split into three groups: one using the brain-controlled glove, one using the glove without brain control, and one receiving …

This study tests whether clot-busting drugs (alteplase or tenecteplase) are safe and effective for stroke patients who have taken a blood thinner (FXa inhibitor) in the last 48 hours. Current guidelines avoid this treatment due to bleeding concerns, but new evidence suggests it m…

This pilot study tests whether a special PET scan using a tracer called Florbetaben can detect inflamed plaque in arteries of people who recently had a heart attack, stroke, or mini-stroke. The goal is to see if this imaging method can identify unstable plaques that are likely to…

This study compares two ways of performing the Valsalva maneuver during a heart ultrasound to detect a patent foramen ovale (PFO), a small hole in the heart that can cause strokes. About 488 stroke patients will be asked to do both a standard self-directed maneuver and a goal-dir…

This trial tests a non-invasive wrist monitor that continuously checks for arm movement asymmetry, a sign of stroke. It aims to alert healthcare workers quickly, reducing delays in treatment. The study involves 1,200 high-risk surgery patients and focuses on device safety and acc…

This study is testing whether a new digital test battery, Mindmore Distance, can accurately assess thinking and memory skills in people with neurological conditions like stroke, Parkinson's, or multiple sclerosis. Researchers will compare results from home-based computer tests wi…

This study tests a wearable device called Neuralert that monitors patients for signs of stroke. It is designed to alert nurses faster than current methods. The trial involves 50 adults who are at high risk for stroke after heart or blood vessel surgery. Each person wears a device…

This study aims to create a rapid blood test that can tell if a stroke is caused by bleeding or a clot, using a protein called GFAP. Researchers will test this in 527 adults with suspected stroke at the hospital. The goal is to help doctors start the right treatment faster, espec…

This study looks at whether a special type of CT scan (multimodal CT) can more accurately identify the blocked artery in people with medium vessel occlusion stroke. Researchers will compare this method to standard CT scans in 622 adults who had a stroke within the last 24 hours. …

This study is testing whether a simple ultrasound of the optic nerve can quickly detect brain swelling and inflammation in ICU patients with conditions like meningitis, encephalitis, or stroke. Researchers will measure the optic nerve sheath diameter in 200 adults and compare it …

This study is testing a new smart sensor that listens to chest sounds to help doctors screen for pneumonia in people who have had a stroke or are on dialysis for kidney failure. About 50 adults will take part, and the sensor's findings will be checked against chest X-rays. The go…

This study tests a portable EEG device called StrokePointer that ambulance crews can use to detect severe strokes caused by large vessel blockages. Currently, over half of these patients are taken to hospitals that cannot perform the needed clot-removal procedure, causing an aver…

This study is testing a new way to detect motor delays in infants using a special play mat with sensors and a smart toy. Researchers will watch how babies move and interact with the toy, then use AI to spot early signs of disability. The goal is to create an easy, objective tool …

This study tests a special therapy for stroke patients in the hospital to help them avoid falls after they go home. Falls are common after a stroke and can cause injuries or fear of falling. The therapy includes extra exercises and education about fall risks. Researchers will tra…

This study tests whether five weekly video therapy sessions led by trained non-professional counselors can prevent depression in older, low-income stroke survivors who have mild depressive symptoms. Researchers will track 350 participants for up to three months to see if the prog…

This study tests whether hydroxyurea, a drug already used for sickle cell disease, can prevent strokes in 220 high-risk children in Nigeria. Children with sickle cell anemia and abnormal blood flow in the brain will receive low then moderate doses of hydroxyurea. The goal is to s…

This study looks at whether closing a small pouch in the heart (the left atrial appendage) during open-heart surgery can help prevent strokes in people with atrial fibrillation. Researchers will analyze heart tissue, blood, and ECG recordings from 1000 participants to find out wh…

This study tests a wearable neuroprosthesis that uses mild electrical stimulation to help stroke survivors open their hand. Two participants will use the device at home for one year to see if it improves daily activities and quality of life. The goal is to understand how well the…

This study tests a wearable robotic knee device (AKO-R) to help people who have had a stroke walk more symmetrically. Twenty participants will do treadmill and overground walking with the device. Researchers will check safety and measure improvements in step length and stance tim…

This study tests whether repetitive transcranial magnetic stimulation (rTMS) can improve heart rate variability and quality of life in people who have had a stroke. 44 participants will receive either real or sham rTMS for 4 weeks. The goal is to see if this brain stimulation can…

This study tests whether adding immersive virtual reality (VR) to robotic walking rehabilitation is tolerable for people who cannot walk after a stroke. Thirty non-walking stroke patients will try both standard robotic rehab and VR-enhanced sessions. Researchers will measure moti…

This study is testing whether combining two types of electrical stimulation with a robotic arm trainer can help people who had a stroke at least six months ago improve their arm movement. 65 participants will receive 20 sessions over 4-7 weeks. The goal is to see if this approach…

This study compares a home-based telerehabilitation program (Tele-CPASS) to standard in-person therapy for improving arm and hand function after a stroke. Forty-two recent stroke survivors with arm weakness will be randomly assigned to receive 20 hours of either remote or in-pers…

This study tests whether a spinal cord stimulator, combined with physical therapy, can help people who have had a stroke regain arm and hand movement. Twenty adults with long-term arm weakness will first do therapy alone, then get a spinal implant and repeat therapy with stimulat…

This study tests whether a gentle, non-invasive nerve stimulation (called tVNS) applied to the ear or neck can improve arm movement, thinking, and quality of life when paired with standard therapy in people who had a stroke 3–6 months ago. About 54 adults who had their first isch…

This study tests whether a non-invasive brain stimulation technique called TMS, combined with language therapy, can improve speech in people who have aphasia after a stroke. Researchers will compare real TMS to a sham (fake) version in 63 participants who had a stroke 2 to 6 week…

This study looks at whether adding a modified form of cognitive behavioral therapy (a type of talk therapy) to standard occupational or speech therapy can improve emotional well-being and daily functioning in stroke survivors. The trial will enroll 80 adults who had a stroke at l…

This study tests whether using a soft robotic hand together with electrical stimulation can help stroke survivors regain hand movement faster than using either therapy alone. About 64 adults who had a stroke 3-6 months ago will receive 40-minute sessions three times a week for 8 …

This study tests whether a new type of virtual reality therapy can improve arm function in people who had a stroke. Fifty-four participants will try different versions of mirror therapy, some with added attention-focusing techniques. The goal is to see which approach works best f…

This study tests whether adding telerehabilitation (home-based, supervised and independent arm exercises) to usual care improves arm function and reduces disability after a stroke. Twenty adults in Brazil who had a stroke about 4 months ago will participate. The goal is to see if…

This study tests a mixed-reality system called RehAtt to help people recover movement after a stroke. Ten participants with one-sided weakness will use the system for arm, walking, and balance exercises. Researchers will interview them to see if the system is easy, motivating, an…

This study tests whether combining low-intensity resistance training with blood flow restriction therapy can improve arm strength, reach, and sensation in people who have had a stroke. Researchers will enroll 64 adults aged 50–70 who are at least one month post-stroke. The goal i…

This study tests whether a twice-weekly exercise program can improve sleep quality in people who had a stroke at least a year ago and currently have poor sleep. 62 participants aged 55 and older will take part in 60-minute classes over 6 months. The goal is to see if exercise can…

This study tests whether lower limb sensorimotor training (exercises that improve touch and movement awareness) or whole-body vibration therapy (standing on a vibrating platform) can help stroke survivors aged 50-65 improve their balance and reduce fear of falling. Fifty-two part…

This study tests whether a special needle treatment guided by ultrasound can help people who had a stroke walk faster and move better. Thirty adults who can already walk 10 meters will either get regular physiotherapy alone or physiotherapy plus this nerve stimulation. Researcher…

This study tests whether adding a wearable vibratory device to standard physiotherapy helps improve arm function in people with hemiplegia (paralysis on one side) after a stroke. Thirty adults who had a stroke 3 to 6 months ago will be split into two groups: one gets usual therap…

This study tests whether vagus nerve stimulation (VNS) paired with rehabilitation can improve leg and walking function in people who have had an ischemic stroke. Researchers will enroll 24 adults who are already approved for VNS therapy for arm problems. The goal is to see if thi…

This study tests a training method called MINT that helps stroke survivors reduce abnormal muscle co-activation in their legs. The goal is to improve walking speed and endurance. Researchers will enroll 72 adults who had a stroke at least 6 months ago and have moderate to severe …

This study tests whether a home-based telerehabilitation program, using games, exercises, and video calls with therapists, can improve arm function and reduce disability in people who had a stroke 90-150 days ago. 202 participants will be randomly assigned to receive telerehabili…

This study compares two types of exercise programs—pelvic proprioceptive neuromuscular facilitation and multiplanar trunk training—to see which one better improves balance and functional mobility in people who have had a stroke. The trial will involve 48 chronic stroke survivors …

This study tests a low-intensity brain stimulation method called kTMP to help people who had a stroke at least 12 months ago improve arm and hand movement. About 12 adults aged 18-80 with moderate arm weakness will receive kTMP alongside motor rehabilitation. The goal is to see i…

This small study tests whether electrical stimulation of the spinal cord can improve arm and leg movement in people who had a stroke at least 6 months ago. Only 6 participants with limited recovery will receive the treatment. The goal is to see if it is safe and helps with daily …

This study tests whether a special swallowing exercise using a pressure-measuring ball can help older stroke patients with swallowing problems. Participants will do the exercises at home twice daily for 12 weeks. The goal is to see if it improves swallowing function and quality o…

This study tests whether home-based telerehabilitation can help stroke survivors who did not get outpatient rehab improve arm and hand function. Two hundred participants across Alberta will use the Tenzr system, which includes fun, game-like exercises with wearable sensors guided…

This study tests whether adding a gentle electrical current to the brain (tDCS) during intensive arm therapy helps women recover arm movement after a stroke. Twenty-four women will receive either real or fake stimulation over two weeks. The goal is to see if the combo improves ar…

This early study tests a device that uses your own breathing to trigger mild electrical stimulation, aiming to reduce hand stiffness and improve hand movement in people who had a stroke at least 6 months ago. Only 4 participants with moderate hand tightness will be enrolled. The …

This study tests a home grip assistance glove (SaeboGlove) to help stroke survivors use their weaker arm in everyday tasks. About 100 adults who had a stroke more than three months ago and have trouble opening their hand will try the glove at home. Researchers will compare how we…

This study tests a special hand device that helps people who had a stroke and cannot open their hand to grab things. The device is designed to let users control it themselves to pick up, move, and release objects like a glass or spoon. Researchers will compare how well 30 partici…

This study tests a gentle, non-invasive brain stimulation technique called tACS to see if it can improve hand and arm movement in people who have had a stroke. Researchers will enroll 14 adults who are at least 6 months past their stroke and have some finger movement. The goal is…

This study compares two physical therapy approaches—rhythmic guided movements and static muscle contractions—to see which better improves arm function, strength, and coordination in people who had a stroke 1 to 6 months ago. Forty participants aged 40 to 60 with arm weakness on o…

This study tests whether a non-invasive brain stimulation technique called rTMS can improve word-finding in people who have trouble speaking after a stroke. Researchers will use MRI scans to guide the stimulation and see how the brain responds. The trial involves 45 participants …

This study looks at whether a hands-on ankle manipulation technique can improve ankle proprioception (the sense of joint position) in people who have had a stroke. Researchers will compare the manipulation to a placebo in 26 stroke survivors, measuring ankle position sense and ra…

This study looks at whether special pelvic stability exercises can improve leg function in people who had a stroke within the past few months. Thirty-four participants will either get pelvic training plus standard leg therapy, or standard therapy alone, for eight weeks. Researche…

This study tests whether combining mindfulness meditation with dual-task training (like walking while doing mental math) can improve thinking and physical skills in people with mild cognitive impairment after a stroke. Sixty participants will be randomly assigned to the combined …

This study tests whether a gentle electrical current applied to the brain can make speech therapy more effective for people with chronic aphasia (trouble speaking or understanding language) after a stroke. About 50 adults who had a stroke at least six months ago will receive eith…

This study tests whether arm therapy done online (telerehabilitation) works as well as the same therapy done in a clinic for people who had a stroke within the last 6 months. 28 participants will be split into two groups, each receiving Constraint-Induced Movement Therapy for 8 w…

This study tests two ways to help stroke patients safely remove their breathing tubes (tracheostomy). One method uses a speaking valve that allows talking, while the other gradually caps the tube. Researchers will compare success rates and safety in 120 patients across multiple h…

This study tests a new robot system (HIWIN MRG-P110) designed to help chronic stroke survivors improve their walking. The robot uses foot pedals to guide leg movements and can adjust how much it helps versus how much the patient must do on their own. Researchers will enroll 60 pe…

This study tests whether a home-based arm exercise program, called GRASP, can help stroke survivors improve movement and use of their affected arm. Participants will do exercises at home for one hour daily and attend group sessions three times a week. The goal is to see if this p…

This study is testing whether combining two types of electrical stimulation can help people who have had a stroke lift their toes while walking. Participants will receive mild electrical currents on their scalp and leg while doing walking exercises. The goal is to see if this com…

This study tests a wearable device that sends gentle, low-frequency electromagnetic fields to the brain to help people who had a stroke more than 6 months ago recover arm movement and reduce disability. About 25 adults with chronic stroke will use the device in a clinic to see if…

This pilot study tests whether a hands-on therapy called Mobilization and Tactile Stimulation (MTS) can help stroke survivors who have unilateral neglect—a condition where they are unaware of one side of their body. Six adults who are at least 20 weeks post-stroke will receive MT…

This study tests whether combining mirror therapy with a soft robotic glove can improve hand function in people who have had a stroke and have weakness on one side. 104 participants will be randomly assigned to receive either standard rehab, mirror therapy alone, the robotic glov…

This study tests a 12-week dance program designed for stroke survivors who have weakness on one side of the body. The program combines movement improvisation and adaptive dance to help improve balance, mobility, confidence, and participation in daily and social activities. Resear…

This study tests whether a gentle, non-invasive electrical stimulation on the ear (called trans-auricular vagus nerve stimulation) can help people recover arm movement after a stroke. About 48 adults who had a stroke within the last 6 months will receive either real or fake stimu…

This study tests a 6-week virtual program called PVI that helps young stroke survivors build personal resources through inclusive volunteering. Researchers want to see if it improves work ability, self-confidence, and emotional well-being. 160 participants aged 18-64 who had a st…

This study tests a program that combines storytelling and practical skills training to help young adults (ages 18-64) who have had a stroke feel more connected and capable in their communities. Over six months, 208 participants will attend eight one-on-one sessions with a facilit…

This study tests a training program for stroke survivors who have trouble paying attention to one side of their world, a condition called spatial neglect. The training teaches mental strategies to improve awareness and daily functioning. Researchers will enroll 45 people living i…

This study tests a new shoe that makes a clicking sound when you walk, designed to help people with foot drop after a stroke. Foot drop makes it hard to lift the front part of your foot, causing tripping. The shoe gives audio feedback to help you walk more naturally. Fifty adults…

This study tests whether a powered exoskeleton can help stroke survivors walk with better balance. Twenty-one people who had a stroke at least six months ago will walk on a treadmill with and without the exoskeleton at different support levels. Researchers will measure how well t…

This study is testing whether combining a special movement therapy with mild electrical stimulation can help people who had a stroke regain arm function. Forty participants who had an ischemic stroke 3 to 6 months ago will receive either the combo therapy or standard rehab. The g…

This pilot study tests whether a 4-week home-based cognitive strategy training program can help adults with chronic stroke become more independent in daily activities like dressing and cooking. Eighteen participants will work with an occupational therapist in their own homes. The…

This study tests a new virtual reality system that uses motion-tracking games to help stroke survivors improve arm and hand function. 56 people who had a stroke within the last 2 to 6 months will either get this VR therapy or standard rehab for 8 weeks. Researchers will measure a…

This study tests whether stimulating the tongue with a non-invasive device can improve arm movement and brain plasticity in people who had a stroke at least six months ago. Participants will do a 4-week strength training program for their affected arm, combined with either real o…

This study tests a special mouth exercise program for people who still have trouble swallowing 12 weeks after a stroke. Researchers want to see if the device can improve swallowing function and quality of life. The trial involves 60 participants and uses a camera test to measure …

This study compares two robotic walking trainers—the Lokomat exoskeleton and the C-Mill treadmill—to see which helps stroke survivors improve their walking and quality of life. About 40 adults who have had a stroke will use one of the devices during rehab. Researchers will check …

This study tests whether a non-invasive device called NESA, which delivers tiny electrical currents through the skin, can help people who had a stroke 6 months to 6 years ago. Researchers will measure changes in pain, muscle tightness, balance, sleep, and daily activities in 30 p…

This study tests whether a device that gently stimulates a nerve in the ear (taVNS) can improve arm and hand function in stroke survivors. Thirty adults who had a stroke within the last five years will receive either real taVNS or a sham (fake) stimulation combined with physical …

This study is testing a device called SynPhNe that stroke survivors can use at home to retrain their hand function. The goal is to see if it improves hand movement compared to standard care alone. The study will include 40 adults who had a stroke at least 6 months ago and have mo…

This study tests two treatments for muscle stiffness in the lower leg after a stroke: Botox injections (a single session) and dry needling (12 weekly sessions). Researchers will measure changes in muscle reflexes and thickness in 90 participants across Belgium, Spain, and Canada.…

This study tests whether high-intensity interval training (short bursts of fast walking) is better than moderate-intensity walking for improving walking ability in people who had a stroke at least 6 months ago. 156 participants will be randomly assigned to one of two 12-week exer…

This study tests whether adding gentle vibration to hand exercises helps stroke survivors regain hand movement, feeling, and reduce muscle tightness. About 38 people who had a stroke at least 3 months ago will be randomly assigned to either standard hand exercises or the same exe…

This study tests whether a program of physical activity counseling and a personalized exercise plan can help stroke survivors become more active. Researchers will compare a group receiving this program plus usual care to a group receiving only usual care. The study involves 120 c…

This study tests a web-based program called CARE-CITE that teaches family caregivers how to better support stroke survivors with arm exercises at home. The program includes virtual home visits and phone check-ins over four weeks. Researchers will measure improvements in arm funct…

This study tests a group-based self-management program delivered via telehealth for people who had a mild or moderate stroke within the last 6 months. The program teaches problem-solving and goal-setting skills to improve daily activities and community participation. Researchers …

This study tests whether a smart board device can help people with arm weakness from brain disorders (like stroke or brain injury) do rehab at home. Forty adults will either use the smart board or a workbook for 4 weeks. The goal is to see if the smart board improves arm function…

This study compares three types of walking training for people who have had a stroke: forward walking with body support, backward walking with body support, and virtual reality-assisted walking. The goal is to see which method best improves walking ability, balance, and overall f…

This study tests whether practicing driving skills in a simulator can improve real driving performance in veteran stroke survivors. One hundred participants will complete both active training (focusing on speed, lane position, collision avoidance, and attention) and a control ses…

This study tests whether personalized brain stimulation (rTMS) can improve arm movement in people who had a stroke within the past 3 months. About 120 participants will receive either a tailored treatment based on their brain's recovery potential or a standard approach. The goal …

This study tests a new speech therapy technique for people with aphasia (trouble speaking) after a stroke. Instead of copying a therapist's voice, participants will practice speaking along with an AI-cloned version of their own voice. The goal is to see if this personalized appro…

This study tests whether wearing ring and wrist sensors and seeing your own movement data on a smartphone can encourage stroke survivors to use their affected arm more during daily activities. Fifty chronic stroke survivors (more than 12 months post-stroke) will wear the sensors …

This study tests a treatment called repetitive transcranial magnetic stimulation (rTMS) for people who have had a stroke more than six months ago and still feel very tired. Fatigue is a common problem after a stroke that can make daily activities hard. The researchers will give r…

This study is testing whether a 10-week music-based program done at home on a tablet can help people recover from a stroke. The program includes rhythm exercises, singing, playing a xylophone, and listening to music. Researchers will compare 100 stroke survivors who do the music …

This study tests whether a non-invasive brain stimulation technique called high-frequency rTMS can improve cognitive problems that often follow a stroke. Researchers will use brain imaging to see how the treatment affects brain activity. The trial aims to enroll 40 adults aged 35…

This study looks at whether adding music training and group leisure activities to standard hospital rehab helps people recover better after a stroke. About 90 adults who recently had a stroke will be split into three groups: usual rehab, usual rehab plus individual music training…

This study tests whether numbing a nerve in the arm or leg can reduce the severe, hard-to-treat pain some people feel after a stroke. Researchers will give 36 adults either one of two numbing medicines or a saltwater injection, then measure pain changes. The goal is to see if blo…

This study tests whether a digital program on an iPad, combined with learning thinking strategies, can improve mood and mental skills in people who have had a stroke. The study will include 70 adults who had a first stroke at least 6 months ago and now have depression and trouble…

This study tests whether a special brain-training game can help people who have had a stroke regain movement in their hand. The game uses a headband to measure brain activity and rewards concentration by moving a virtual hand. The study will include 30 people who had a stroke wit…

This study compares three rehabilitation approaches for people recovering from a stroke: mirror therapy (using a mirror to trick the brain into thinking the affected limb is moving), cognitive orientation to daily occupational performance (CO-OP, a problem-solving strategy to ach…

This study tests whether a new virtual reality therapy that combines mirror therapy with cooperative tasks can improve arm movement in people who had a stroke at least six months ago. Forty-four participants will be split into groups receiving either standard task-oriented traini…

This study tests whether adding a vibrating device (Vibramoov®) to robotic walking training helps stroke survivors walk better than robotic training alone. Forty adults who had a stroke at least 3 months ago will take part in a 4-week rehab program. Researchers will measure walki…

This study is testing a device called MyHand 2 that helps people who have had a stroke use their affected hand better. The device is worn on the hand and assists with movement. Researchers want to see if it is easy to use and helpful for daily tasks. The study involves 60 adults …

This study tests whether low-intensity focused ultrasound, a non-invasive technique, can help stroke patients regain arm and hand movement. Fifty adults who had a stroke within the past three months and have some arm weakness will receive either real or sham ultrasound daily for …

This study is testing whether adding sensory training to a proven arm therapy (Constraint-Induced Movement therapy) can help stroke survivors with mild-to-severe arm and hand weakness. Researchers will enroll 15 adults who are at least 6 months post-stroke. The goal is to see if …

This study tests three different naming treatments for people with aphasia, a language disorder often caused by stroke. The goal is to see which approach best helps participants remember words and use them in daily life. Thirty adults with chronic aphasia will practice naming pic…

This study tests whether training one arm alone or both arms together is better for recovering arm and hand function after a stroke. Thirty-two adults who had a stroke 6 to 24 months ago will do task-specific exercises for 4 weeks. Researchers will measure motor recovery and hand…

This study tests a wearable device called a myoelectric-computer interface (MCI) that helps stroke survivors improve arm movement by reducing abnormal muscle co-activation. The device uses muscle signals to guide a video game, providing feedback to retrain coordination. Researche…

This study tests a non-invasive treatment called extracorporeal shockwave therapy to improve arm and hand function in people who had a stroke at least 6 months ago. The therapy uses sound waves to reduce muscle tightness and improve movement. Researchers will measure changes in a…

This study is testing whether backward walking training can help stroke survivors improve their gait and balance. About 48 veterans who had a stroke 2-4 months ago will receive either 18 or 27 sessions of backward walking on a treadmill and over ground. Researchers will also use …

This pilot study tests whether a 12-week sitting Tai Chi program can improve cognitive function, arm movement, balance, and mood in chronic stroke survivors who have memory or thinking problems. About 176 participants (88 stroke survivors and 88 caregivers) will be randomly assig…

This study tests whether virtual reality (VR) training in a simulated home environment can improve arm and hand function in people recovering from a stroke. Researchers will compare VR-based task-oriented training to standard therapy in 86 participants. They will also use brain s…

This study tests whether adding music-like sounds (sonification) to standard walking rehabilitation can improve gait, balance, and quality of life. 120 adults with Parkinson's disease, stroke, or multiple sclerosis will be randomly assigned to standard rehab or rehab with sonific…

This study compares two ways to help stroke survivors improve their thinking skills: doing cognitive exercises at home via video sessions (tele-rehabilitation) versus doing them in person at a clinic. Researchers will enroll 32 adults aged 50-80 who have mild to moderate cognitiv…

This study looks at whether walking on a treadmill can improve how stroke survivors move. Many people who have had a stroke walk unevenly and have different skin temperatures on their affected side. The researchers will measure changes in walking speed, endurance, and body heat p…

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can improve breathing muscle strength in people who had a stroke 1-3 years ago. Researchers will measure lung function in 50 participants before and after treatment. If successful, TAVNS coul…

This study tests whether a powered exoskeleton can improve walking and daily function for people recovering from a stroke. About 50 participants in inpatient rehab will use the device during therapy. Researchers will measure changes in walking distance, independence, and muscle s…

This study tests whether biofeedback—a technique that shows you real-time visuals of your swallowing—can help stroke survivors with swallowing problems recover faster. One hundred participants will be split into two groups: one gets standard therapy with verbal feedback, the othe…

This study compares different types and intensities of walking therapy for people who had a stroke 1-6 months ago. 100 participants will receive up to 30 one-hour sessions of either high- or low-intensity walking or general physical therapy. The goal is to see which approach best…

This study tests whether high-intensity interval training (HIIT) on a recumbent stepper can improve muscle power in people who have had a stroke. 66 chronic stroke survivors aged 50-80 will be randomly assigned to HIIT, moderate-intensity continuous training, or stretching for 12…

This study tests whether adding virtual reality balance and walking exercises to standard physical therapy helps people recovering from a stroke. Forty-eight adults with subacute stroke will be randomly assigned to either standard rehab alone or standard rehab plus 15 sessions of…

This study is testing a mobile app called MAYA that provides cognitive behavioral therapy (CBT) to help adults who have had a stroke manage anxiety and depression. About 10 participants aged 40-79 will use the app and provide feedback on how easy and helpful it is. The goal is to…

This study tests whether adding visual biofeedback to standard swallowing exercises and electrical stimulation helps stroke patients with swallowing problems. 34 adults who had a stroke in the last 6 months will be randomly assigned to either the biofeedback group or a convention…

This pilot study tests whether a mild electrical stimulation applied to the spinal cord, combined with balance training, can improve stability and reduce fall risk in people who had a stroke over a year ago. Sixteen community-dwelling adults will be randomly assigned to receive e…

This study compares prism adaptation training (PAT) alone versus PAT combined with mild electrical stimulation (TENS) in 20 stroke survivors who have unilateral spatial neglect—a condition where they ignore one side of their body. The goal is to see if the combination improves at…

This study tests whether a mild electrical current applied to the back of the brain (cerebellar tDCS) can boost language therapy for people who have trouble finding words after a stroke. Sixty adults who had a left-hemisphere stroke at least six months ago and still have aphasia …

This study tests two new therapy systems that use virtual reality (VR) or mixed reality (MR) to help stroke survivors improve arm function. Participants will perform movements while watching a mirrored hand in a headset. The trial aims to see if these high-tech approaches are fea…

This study tests whether adding functional electrical stimulation (FES) to arm cycling exercises improves aerobic fitness and arm function in people who had a stroke within the last 6 months. 24 participants will be split into two groups: one doing arm cycling alone, the other do…

This study tests whether adding rhythmic music cues to treadmill walking with mental tasks improves walking ability and social life in people who had a stroke at least 6 months ago. 90 participants will be split into three groups: treadmill only, treadmill with cognitive tasks, o…

This study tests whether adding one hour of arm-hand exercises daily (5 days a week for 4 weeks) to usual care helps stroke patients regain arm function. 80 people who had a stroke within the last 5 months will be randomly assigned to either the extra arm-hand program or a lower-…

This study tests a non-invasive device that sends mild electrical pulses to the spinal cord to improve walking and balance in people who have weakness on one side after a stroke. About 115 adults who are at least 6 months post-stroke will participate. Researchers will measure cha…

This study tests two advanced rehabilitation methods—robot-assisted walking training and visual feedback balance training—to see which better improves balance and walking in people who have had a stroke. About 60 adults with subacute or chronic stroke will participate in 4 weeks …

This study tests whether a device that creates a visual illusion of movement can help people who had a stroke regain use of their arm and hand. About 66 participants will either get standard therapy or standard therapy plus sessions with the device. The goal is to see if the devi…

This study compares mirror therapy, brain stimulation (rTMS), and robotic hand training added to standard rehab for stroke patients. 120 adults who had a stroke at least 3 months ago will receive 20 sessions over 4 weeks. The goal is to see which approach best improves arm functi…

This study tests whether combining neuromuscular electrical stimulation with mindfulness breathing exercises can improve lung function, physical abilities, and stress levels in stroke survivors. Sixty stroke patients aged 50-65 will be randomly assigned to receive either stimulat…

This study is testing whether a robotic device called Pablo Tyromotion, combined with standard physical therapy, can improve arm and hand function in people who had a stroke months or years ago. 120 participants aged 45-80 with some remaining arm weakness will undergo 4 weeks of …

This early study tests whether a device that sends electrical pulses to muscles and the spinal cord can improve arm, hand, or leg movement in people with paralysis from spinal cord injury, stroke, or other nerve damage. Up to 64 participants will attend sessions five times a week…

This study looks at how much walking practice on a special treadmill (split-belt) with virtual reality stroke survivors can handle in early recovery. About 72 people who had their first stroke within the past three months will try different amounts of training to find the safest …

This study tests a smartphone app called ICanWALK that teaches people how to properly fit and use walking aids like crutches, canes, and walkers. Researchers will compare it to a breathing app in 52 adults with lower limb injuries or conditions like stroke or multiple sclerosis. …

This study tests whether adding neuromuscular electrical stimulation (NMES) to standard facial exercises helps people who have facial paralysis after a stroke. About 130 adults with first-time stroke and central facial palsy will be randomly assigned to receive either usual train…

This study tests a new program where stroke survivors coach other stroke survivors to improve well-being and quality of life. Researchers will check if the program is practical and liked by both coaches and recipients. The study involves 20 adults who had a stroke within the past…

This study compares digital mirror therapy using augmented reality to conventional mirror therapy for improving arm function in people who had a stroke at least 6 months ago. 44 participants will receive 10 sessions over 21 days. The goal is to see if the digital version leads to…

This study tests a new rehabilitation method for people who lost part of their vision after a stroke. It combines gentle electrical brain stimulation with visual exercises, sometimes using virtual reality, to try to speed up recovery of sight in the blind area. The study involves…

This study tests whether a 12-week home telerehabilitation program using the MindMotion GO device can help stroke survivors improve motor function. 51 participants who had a stroke more than 30 days ago will use the device for 300 minutes of weekly therapy, guided remotely by a t…

This study tests whether a smartphone or computer app that uses artificial intelligence can improve thinking and memory in people who have had a stroke. The study will include 40 adults aged 45 to 60 who have had a stroke at least 3 months ago and still have some memory or thinki…

This study tests whether combining Transcranial Magnetic Stimulation (TMS) with speech therapy can improve language in people with mild aphasia after a stroke. About 24 adults who had a left-brain stroke at least 6 months ago will receive either real or fake TMS along with 10 day…

This study tests whether using EEG neurofeedback — a way to train brain activity — can improve arm movement in people who recently had a stroke. Forty adults with a stroke within the past three weeks will either get real or fake (sham) neurofeedback, plus standard rehab. The goal…

This study tests whether home-based telerehabilitation therapy—hand and arm exercises prescribed by an occupational therapist and done remotely—is feasible and helpful for stroke survivors with vascular dementia. The main goal is to see if it lessens the burden on family caregive…

This study compares two modern therapies—mirror therapy and virtual reality (VR)—to see which better improves arm function in people with hemiplegia after a stroke. Forty-two participants aged 18-75, who had a stroke 6-12 months ago, will be randomly assigned to one session of ei…

This study tests whether a personalized form of brain stimulation (tDCS) can help people who had a stroke more than 3 months ago regain arm movement. Researchers will use brain scans to tailor the stimulation to each person and measure changes in brain connectivity and motor func…

This study tests whether a non-invasive nerve stimulation (taVNS) combined with occupational therapy can improve arm movement in people who had a stroke at least 6 months ago. 60 participants will receive the stimulation during therapy sessions. The goal is to see if this approac…

This study tests a hand exercise program for children aged 7 to 12 who have had a stroke and have trouble using their arm or hand. The program involves many repetitions of strength and coordination exercises. The goal is to see if these exercises improve how well children can use…

This study tests whether injecting hyaluronidase into the shoulder muscles can relieve pain and stiffness in stroke survivors. About 68 participants will receive either the drug or a placebo injection. Researchers will use MRI and ultrasound to measure changes in muscle health an…

This study looks at whether playing music during routine hygiene care (like bed baths) can improve comfort for stroke patients in the intensive care unit. About 102 adults who recently had a stroke will take part. After care, patients will rate their comfort using a simple pictur…

This study tests whether watching videos of functional activities and then performing them, combined with rhythmic music, can improve balance and walking in people who had a stroke. Forty participants will be split into two groups: one doing the video-and-music therapy and the ot…

This study tests whether a program called Task-Oriented Circuit Training (TOCT) can improve arm and hand function in people who have had a stroke. TOCT involves 15 exercise stations that focus on practical tasks. The study will compare TOCT to standard occupational therapy in 24 …

This study tests whether a technique called biofeedback can help people who have had a stroke improve movement in their arms and hands. Researchers will measure changes in motor skills and grip strength. The goal is to see if this type of training leads to better recovery.

This study tests whether special knee strengthening exercises can improve balance and body awareness (proprioception) in people who had a stroke. About 34 participants who had a stroke 3 months to 1 year ago will do either isokinetic knee exercises or standard rehab. The goal is …

This study compares two ways of using a robotic device to help people with chronic stroke regain arm function. About 72 participants will receive 18 sessions of robotic training over 6 weeks, either starting with the forearm or the wrist. Researchers will measure arm movement, st…

This study tests whether adding a type of brain stimulation (called continuous theta burst stimulation) to mirror therapy can improve hemispatial neglect in people who have had a stroke. Neglect means the brain ignores one side of the world, often the left. Twenty-two stroke surv…

This study tests if a less invasive freezing technique (cryoneurotomy) works as well as surgery to reduce foot stiffness in people who had a stroke. About 114 adults with chronic foot spasticity will be randomly assigned to one of the two treatments. The goal is to see if the fre…

This study tests whether task-based mirror therapy can reduce pain, swelling, and improve arm function in stroke survivors who develop shoulder-hand syndrome. Thirty-four participants aged 45-75 will be split into two groups: one doing mirror therapy plus standard exercises, the …

This study tests whether a gentle electrical stimulation to the ear (vagus nerve) combined with arm nerve stimulation can improve arm function in people who had a stroke at least 6 months ago. 120 participants aged 55-75 will receive either real or sham stimulation. The goal is t…

This study tests a 4-week program that combines virtual reality training in a simulated shopping mall with real-world walking practice for stroke survivors. The goal is to improve community ambulation and participation. Forty chronic stroke survivors will be enrolled, and researc…

This study tests a therapy called Constraint-Induced Movement (CI) Therapy for adults who had a stroke at least 6 months ago and have mild weakness in one arm. The therapy involves daily training to improve arm and hand use, along with strategies to encourage using the weaker arm…

This study is testing a powered ankle exoskeleton—a robotic brace—to see if it can help people who have had a stroke walk with less effort. About 15 stroke survivors will walk on a treadmill and over ground with the device. Researchers will measure how much energy they use and ho…

This study tests whether virtual reality exercises can improve attention problems in people who have had a brain injury, like a stroke or traumatic brain injury. About 135 participants will either do VR-based cognitive games or standard pen-and-paper exercises for 20 sessions. Th…

This study tests whether psilocybin, a psychedelic substance, is safe for people who had a stroke at least a year ago. Researchers will monitor blood pressure and other vital signs in 20 participants. The goal is to see if psilocybin can help with lingering symptoms like weakness…

This study tests a smartphone app called Zenicom that provides personalized speech therapy exercises for people who have trouble speaking after a stroke (aphasia). Twenty adults with recent stroke and aphasia will either receive standard speech therapy alone or standard therapy p…

This study tests a new virtual reality system that combines mirror therapy with interactive games to help people recover arm movement after a stroke. Researchers will enroll 172 participants, including both healthy individuals and stroke survivors, to see if the system is comfort…

This study tests whether using a robotic exoskeleton for walking practice helps stroke survivors recover their ability to walk better than standard physical therapy. The trial will enroll 54 adults who are in the early weeks after a stroke and are staying at a rehabilitation hosp…

This study tests whether a gentle brain stimulation technique called rTMS, given just before walking-and-thinking training, can improve mobility and mental sharpness in people who had a stroke at least 6 months ago. 184 participants will receive either real or fake rTMS before 12…

This study looks at two ways to help people who had a stroke more than 6 months ago get more physical activity. One group will follow a personalized exercise program at a special facility, while the other group will do their own program at home. The goal is to see which approach …

This study tests whether adding pelvic coordination exercises to standard core strengthening helps people recovering from a stroke improve their trunk control and balance. Researchers will compare this combined approach to standard trunk exercises alone in 38 adults aged 45-60 wh…

This study tests whether a virtual reality system that helps move a virtual hand using muscle signals, combined with mild brain stimulation, can improve arm function in stroke survivors. 45 people who had a mild to moderate stroke will try this approach. The goal is to see if thi…

This study tests whether combining a brain-computer interface with virtual reality can improve arm and hand movement in stroke survivors. Twelve adults who had a stroke 6 to 24 months ago will each try both the VR-enhanced training and a standard brain-computer interface training…

This study tests whether a smartphone app, used alongside standard care, can improve swallowing recovery in stroke patients who have trouble swallowing. About 74 adults who had a stroke and now have swallowing issues will either get usual care alone or usual care plus the app. Th…

This study tests whether sensor-based robotic arm rehabilitation can improve both thinking skills (like memory and attention) and physical movement in adults with Parkinson's disease, multiple sclerosis, or stroke. Participants will receive 25 sessions of either robotic therapy w…

This study looks at whether doing high-intensity walking training more often helps people who had a stroke more than six months ago improve their walking ability. Forty adults will be assigned to either frequent or less frequent training sessions, plus a home walking program. The…

This study looks at whether a special type of electronic moxibustion, based on the Ziwu Liuzhu theory, can help stroke patients who have constipation. Researchers will compare using this moxibustion alone versus combining it with ear acupressure. The goal is to see which approach…

This study looks at whether adding virtual reality therapy to standard rehabilitation and action observation therapy can improve arm and hand function in people who had a stroke 6 weeks to 6 months ago. About 38 adults will be split into two groups: one gets standard care plus ac…

This pilot study tests whether a virtual reality program that stimulates the visual and balance systems can help stroke survivors improve their balance and walking. 38 participants, at least 6 months past their stroke, will be randomly assigned to either the real VR training or a…

This study tests whether combining a special audio-visual training with mild brain stimulation can help people who lost part of their vision after a stroke. Forty-eight participants in the early recovery phase will either get real or fake brain stimulation during daily 90-minute …

This study is testing whether a special vibration device, used along with standard rehab, can improve muscle strength, movement, and pain in older adults and stroke survivors. About 80 participants will receive either vibration therapy plus rehab or rehab alone. The goal is to se…

This study is testing whether adding robotic exoskeletons and virtual or augmented reality to treadmill training can help people who have had a stroke walk better and feel more independent. Researchers will compare different training methods in 80 participants to see which works …

This study tests whether a suprascapular nerve block (a numbing injection) plus physical therapy can improve shoulder joint awareness and reduce pain in stroke survivors with hemiplegic shoulder pain. Fourteen participants will be randomly assigned to receive either the nerve blo…

This study tests whether using a mobile breathing trainer (AiroFit PRO™) for 6 weeks can improve lung function, muscle strength, and quality of life in people with hemiplegia (paralysis on one side) after a stroke. 54 adults who are at least 3 months post-stroke will be randomly …

This study is testing a wearable suit called Mollii that uses mild electrical stimulation to improve mobility and quality of life in people who have had a stroke or have multiple sclerosis. Forty participants will wear the suit for one hour, three times a week for four weeks. Som…

This study tests a wearable sensor that tracks neck muscle activity during swallowing exercises, providing real-time feedback to patients. Researchers want to see if adding this device to standard therapy improves swallowing more than therapy alone. The study includes 120 adults …

This study tests a new soft robotic glove designed to help people who have had a stroke regain movement in their wrist and hand. Sixty participants will use the glove in 20 training sessions, and their progress will be compared to those receiving standard therapy. The glove uses …

This study looks at whether adding aerobic exercise (like walking or cycling) to standard physical therapy can help stroke survivors recover better. The goal is to improve arm movement, thinking, and mood. About 40 people who had a stroke at least 6 months ago will take part. Res…

This study tests a non-invasive method called sensory augmentation for people who have had a stroke at least 6 months ago and still have balance problems. Small vibrations are applied to the skin to enhance the body's natural sense of position, aiming to make standing steadier an…

This study tests a smartphone app that uses virtual and augmented reality to help people who had a stroke improve arm movement and thinking skills from home. Seventy chronic stroke patients will either use the app or receive standard care for six weeks. The main goal is to see if…

This study tests a new type of mirror therapy to help people who have had a stroke regain movement in their arm and hand. The therapy uses a mirror to show the unaffected arm moving, which tricks the brain into thinking the affected arm is moving too. 81 participants will receive…

This study tests whether a robotic exoskeleton combined with video games can improve arm movement in people who recently had a stroke. The device restricts certain movements to help patients relearn natural motion without using bad habits. The trial will enroll 44 participants in…

This study tests whether combining virtual reality training with a gentle brain stimulation technique can improve arm and hand movement in people who had a stroke at least three months ago. Researchers will enroll 100 adults to compare the effects of this combination on motor ski…

This study tests a 10-week power exercise program for people who had a stroke at least 6 months ago. Researchers want to see if it improves walking, strength, and balance better than standard strength training. Sixty participants will be randomly assigned to either the power prog…

This study tests a new AI system that guides stroke survivors through arm exercises at home. About 192 people who had a stroke at least 6 months ago will use a video game-like rehab tool, with or without AI help, or receive standard care. The goal is to see if the AI version impr…

This study tests whether a precise form of brain stimulation called targeted high-definition tDCS can reduce arm stiffness and improve movement in 30 people who have had a stroke. The treatment aims to calm overactive brain pathways and boost damaged ones. Participants will recei…

This study tests whether a tongue endurance exercise program can improve swallowing in adults who have had a stroke. Seventy participants will be randomly assigned to either the tongue exercise group or a sham therapy group. They will do home-based exercises for 8 weeks and have …

This study tests whether training on a virtual reality treadmill is practical and helpful for people who had a stroke at least 6 months ago. Thirty participants will either use the VR treadmill or do traditional exercises for 45 minutes, three times a week for 12 weeks. The goal …

This study looks at whether adjusting deep brain stimulation (DBS) can improve movement, speech, and swallowing in people already implanted with DBS for conditions like tremor, stroke, or traumatic brain injury. Researchers will test hand dexterity, grip strength, facial movement…

This study tests a walking meditation program called iWalk for adults with neurodegenerative diseases like multiple sclerosis. The goal is to see if it's feasible and helps improve resilience, stress regulation, and thinking skills. Researchers will enroll 90 participants and mea…

This study tests whether adding action observation (watching movements) and motor imagery (imagining movements) to standard physical therapy can improve balance, daily function, and quality of life in people who had a stroke within the last year. About 56 participants will be ass…

This study looks at whether a gentle nerve stimulation (tVNS) combined with hand therapy (mCIMT) can help people who had a stroke more than 6 months ago improve arm movement, thinking, and daily life. 50 adults with chronic stroke will be split into two groups: one gets both trea…

This study looks at two types of exercise—high intensity interval training and intermittent functional training—to see which one better helps stroke survivors improve their heart fitness, physical abilities, and thinking skills. About 52 adults aged 50-75 who had a stroke at leas…

This study tests whether adjusting the timing of speech therapy sessions can help people with aphasia (trouble speaking after a stroke) remember words better and use them in daily life. About 32 adults with chronic aphasia will practice naming pictures using a computer program th…

This study tests whether high-intensity interval training (HIIT) can reduce fatigue in people who have had a stroke. Sixty chronic stroke survivors with fatigue will be randomly assigned to HIIT, moderate exercise, or stretching for 12 weeks. The main goal is to see if the progra…

This study tests whether a modified cardiac rehabilitation program—combining aerobic and strength exercises—can improve physical function and reduce depression in people who had a stroke at least six months ago. Researchers will enroll 76 participants, some with depression and so…

This study tests whether adding vestibular (inner ear/balance) exercises to standard physical therapy can reduce fatigue and improve balance and walking in people who had a stroke at least 6 months ago. Thirty adults aged 18–65 will be split into two groups: one gets standard reh…

This study tests whether combining a gentle nerve stimulation (taVNS) with robot-assisted arm training helps stroke survivors regain arm function better than robot training alone. Thirty adults who had a stroke at least 6 months ago and have moderate to severe arm weakness will p…

This study tests whether a gentle nerve stimulation (taVNS) combined with robot-assisted arm training can help stroke survivors regain arm movement, breathing strength, and quality of life. Thirty adults who had a stroke at least six months ago will receive either real or fake st…

This study tests whether dry needling (inserting thin needles into tight muscles) can reduce spasticity—stiffness that makes movement hard—in people who have had a stroke. About 28 adults who can walk independently will receive either real or sham (fake) needling once a week for …

This study tests whether a technique called flossing (using a stretchy band around the shoulder) can reduce pain, improve movement, and help sleep in people who have had a stroke and have shoulder pain. About 40 adults aged 30-55 who are at least 6 months post-stroke will take pa…

This study tests whether applying kinesio tape to the neck muscles can improve swallowing safety in people who have trouble swallowing after a stroke. Researchers will measure changes in swallowing using a special X-ray video before and right after the tape is applied. The study …

This study explores whether hypnosis can help people with stroke, traumatic brain injury, or multiple sclerosis improve their attention and reduce fatigue. About 48 participants will receive hypnosis sessions alongside standard care, while researchers monitor brain activity with …

This study tests a wrist-worn sensor system called StrokeWear that gives feedback and encourages stroke survivors to use their weaker arm more during daily activities. 88 people who had a stroke 1-6 months ago will either use the system plus a home exercise plan, or just the exer…

This study looks at whether Vojta therapy, a type of physical therapy that uses gentle pressure on specific body areas to trigger natural movement patterns, can improve posture and trunk control in people recovering from a stroke. Researchers will include 62 adults aged 45-65 who…

This Phase 2 trial tests a wrist-worn sensor system called StrokeWear, combined with goal-setting and daily action planning, to encourage stroke survivors to use their weaker arm more during everyday activities. The study enrolls 32 chronic stroke survivors who will either use th…

This study compares two types of exercise programs—trunk training and lateral balance training—to see which better improves trunk control, balance, and daily activities in people who have had a stroke. Researchers will enroll 44 participants aged 40-75 who are at least six months…

This study tests a non-invasive brain stimulation technique called iTBS to see if it can improve balance and leg movement in people who had a stroke more than six months ago. Researchers will measure changes in walking and brain activity. The goal is to find a safe, practical way…

This study tests whether injecting Xeomin® into the upper arm can improve walking and quality of life in adults who have weakness on one side after a stroke. Twenty participants will be measured before and 4-6 weeks after the injection using walking tests and a sensor. The goal i…

This study tests whether a non-invasive brain stimulation technique called intermittent theta burst stimulation (iTBS) can improve arm and leg movement in people who had a stroke more than six months ago. 48 participants will receive either real or sham stimulation over 15 sessio…

This study compares robot-assisted training to standard physical therapy for people who have had a stroke and still have moderate-to-severe movement problems. Forty participants who are 6-24 months post-stroke will be randomly assigned to one of two training programs. The goal is…

This study tests whether ankle braces made with 3D scanning and printing work as well as those made the old-fashioned way with plaster casts. About 50 people aged 8 and older with leg weakness from conditions like cerebral palsy, stroke, or spinal cord injury will try both types …

This study tests whether a digital program called Sleepio, which uses cognitive behavioral therapy for insomnia, can improve sleep in stroke survivors. Researchers will also see if better sleep helps with learning motor skills overnight. About 100 adults who have had a stroke and…

This study tests whether simple, passive robotic devices can help people who have had a stroke regain arm and hand movement. Four participants will use the devices during reaching exercises, sometimes with electrical stimulation to activate muscles. The goal is to see if this app…

This study is testing a special suit called the Neuro20 that uses mild electrical pulses to stimulate muscles in the arms, legs, chest, and back. Researchers want to see if wearing it during therapy sessions can improve walking ability, muscle performance, and heart health in peo…

This study tests whether a fast form of brain stimulation, called accelerated rTMS, can safely improve apathy—loss of motivation and withdrawal—in people who have had a stroke. About 40 adults who had a stroke at least 6 months ago and have significant apathy will receive either …

This study tests whether forced aerobic exercise (using a bike that helps move your legs) can improve arm and leg recovery after a stroke better than traditional therapy. About 66 people who had a stroke 3-9 months ago will take part. Researchers will also check if this approach …

This early study tests a motor-assisted pedaling device called CUped to help stroke survivors recover leg movement and improve walking. The device forces use of the affected leg and prevents bad habits that slow recovery. Only 12 people will take part to check if it is safe, tole…

This study tests whether taking krill oil supplements for 12 weeks can improve muscle strength and function in adults with long-term conditions like diabetes, heart disease, or arthritis. Thirty participants will be randomly assigned to receive either krill oil or a placebo. Rese…

This study tests a new rehab program called ACES, which combines acceptance and commitment therapy with strategy training, to help chronic stroke survivors take part in social activities again. Fifty-four adults who had a stroke at least six months ago and live in the community w…

After a stroke, many people lose the ability to open their affected hand. This study tests three different non-invasive brain stimulation methods combined with hand therapy to see which works best. Researchers will enroll 63 adults who had a stroke 6 to 24 months ago and compare …

This study tests whether extracorporeal shock wave therapy (ESWT) can reduce spasticity—stiff, tight muscles—in the wrists of people who had a stroke at least six months ago. Researchers will give 32 participants either ESWT plus standard rehab or just standard rehab. They will u…

This pilot study is testing a portable hybrid exoskeleton that combines a robotic arm support with electrical stimulation to help people with upper limb deficits from stroke or brachial plexus injuries. Ten participants will perform tasks like moving blocks and daily activities w…

This small pilot study is testing whether combining two non-invasive treatments—brain stimulation (tDCS) and muscle stimulation (FES)—can help improve hand control in people who had a stroke at least six months ago. The study involves 15 participants and will measure changes in b…

This study tests whether adding gentle vibrations to the arm can help stroke survivors who have lost sense of position better control their movements. Thirty participants will perform reaching and daily tasks like drinking from a glass while wearing a device that provides extra s…

This study explores whether listening to music on purpose, for one hour a day, can improve mental health in people who had a stroke at least six months ago. Sixty participants will be randomly assigned to listen to either music or an audiobook at home for four weeks. Researchers …

This study tests whether watching real-life swallowing movements (like a family member eating) can improve swallowing function in stroke patients with dysphagia. Ninety participants will be split into three groups: standard therapy, therapy plus watching swallowing videos, or the…

This study tests a new behavioral therapy called PICTURE IT, delivered via telemedicine, to help people with aphasia after a stroke. The therapy uses pictures and spoken words to stimulate the right side of the brain, aiming to improve language skills. Researchers will compare it…

This study tests whether escitalopram (Lexapro), a common antidepressant, combined with computer-based naming therapy can improve language recovery in people with aphasia after a stroke. About 88 participants who had a left-hemisphere stroke within the past 5 days will receive ei…

This study tests whether a precise form of brain stimulation (TMS) combined with language therapy can improve word-finding in people who have aphasia after a stroke. Fifty stroke survivors will receive either targeted or control stimulation during therapy sessions. The goal is to…

This study tests whether a gentle electrical current applied to the scalp (tDCS) combined with computer-based cognitive training can improve memory, attention, and thinking in people who had a mild stroke. About 60 participants will receive either real tDCS or a sham (fake) versi…

This study tests whether combining a gentle brain stimulation technique (tDCS) with repetitive arm and hand exercises can help people who have neglect after a stroke. Neglect means they have trouble paying attention to one side of their body or space. The study also aims to combi…

This study tests a new non-invasive brain stimulation technique called mirror-PAS, which combines visual and motor signals to promote brain plasticity. Researchers will compare it to standard brain stimulation in 36 people with stroke-related arm weakness or phantom limb pain. Th…

This study tests whether a personalized exercise program, designed using motion sensors to identify specific walking problems, can improve gait in people who had a stroke at least six months ago. Fifty-two participants will do 12 supervised sessions over six weeks. The goal is to…

This study tests whether virtual reality dance games, like 'Just Dance', can help people who have had a stroke improve their balance and movement. Researchers will compare this fun, home-friendly approach to standard physical therapy. The goal is to see if it's safe, enjoyable, a…

This study tests whether a home-based occupational therapy program using video calls and activity monitoring can help older stroke survivors improve their daily functioning and self-management. Researchers will compare this approach to standard care in 171 participants over 26 we…

This study tests whether adding visual-motor training (using lights to guide movement) to standard physiotherapy can improve arm and hand function in people who have had a stroke. 38 participants will be assigned to either standard therapy alone or standard therapy plus visual-mo…

This study tests whether combining electroacupuncture (mild electric pulses through thin needles) with repetitive transcranial magnetic stimulation (rTMS, a non-invasive brain stimulation) can improve arm and leg movement after a stroke. 180 adults who had their first stroke with…

This study tests whether combining mirror therapy with either mild electrical stimulation or special sound beats can improve leg movement in people who had a stroke at least six months ago. Seventy-two participants will be assigned to one of three groups and will do ankle exercis…

This study tests whether a gentle electrical current applied to the brain (tDCS) can improve arm and hand movement in people who recently had a stroke. Fifty participants with severe arm weakness will receive either real or fake (sham) stimulation during rehab. The goal is to see…

This study looks at how social and lifestyle factors—like education, race, and income—affect a person's thinking and memory after a stroke. Researchers will interview 450 adults who had a stroke and review their brain scans and medical records. The goal is to understand why some …

This study tracks how a touch signal on the finger travels through the nervous system to the brain. Researchers will apply different force levels to the finger and measure when people first feel it, along with brain activity using fMRI. The study includes 60 people: young adults,…

This study uses fMRI and EEG to understand how brain areas that plan movement interact with those that process sound during speech. Researchers will compare healthy adults and people who have had a cerebellar stroke. The goal is to learn how the brain adjusts hearing during speak…

This study explores whether exercising the unaffected leg at home can trigger beneficial brain and spinal changes in people with severe stroke. Participants perform strength and coordination tasks with their stronger leg using a tablet-based system, while researchers measure brai…

This study looks at how taking a nap helps the brain remember new motor skills, like typing a sequence. Researchers will use brain scans to see what happens during rest and sleep. The study includes adults who have had a stroke and healthy volunteers of different ages. The goal i…

This study uses a brain imaging technique called fNIRS to watch how the brain changes during robot-assisted hand therapy in stroke survivors. Researchers will compare two types of robotic devices (end-effector and exoskeleton) to see which one better promotes brain reorganization…

This study tests how Tizanidine, a drug used for muscle stiffness, changes arm movement in people who have had a stroke. Researchers will measure brain activity, muscle responses, and movement patterns in 64 participants. The goal is to understand what limits movement after strok…

This study tests a 12-month community program (SCIP) for older adults in rural Ecuador. It includes group activities, peer support, and home coaching to reduce loneliness. Researchers will measure changes in social isolation, heart health, memory, and mood in 500 people aged 60 a…

This observational study is looking at 250 people who have had a stroke or mini-stroke due to narrowing of arteries in the brain. Researchers want to see if a specific platelet protein (FcγRIIa) and blood flow patterns on MRI can help predict who will have another stroke within a…

This study is collecting medical information and blood/urine samples from 9,500 people with various heart and blood vessel conditions, plus healthy volunteers, over 20 years. The goal is to find better ways to diagnose heart disease and predict how patients will do in the future.…

This study looks at whether a special nursing care model helps people with long-term health conditions like diabetes, heart disease, or Parkinson's work better with their advanced practice nurse. About 420 adults will take part. The goal is to see if this approach improves how pa…

This study tests whether a home-based computer training program can improve vision in people who have lost part of their visual field due to stroke, traumatic brain injury, or brain tumor. Researchers will use brain scans to understand how the brain changes with training. The stu…

This study looks at whether being left-handed or right-handed affects how well people recover arm movement after a stroke. Researchers will follow 500 adults who had a recent stroke for 6 months, measuring arm function with standard tests. The goal is to see if left-handed people…

This study looks at how stroke changes the way the spinal cord handles sensory signals. Researchers will stimulate nerve roots in the neck during surgery and measure muscle and brain responses in 15 people (some with stroke, some healthy). The goal is to better understand spinal …

This study uses a brain imaging technique called MEG to look at how the brain recovers after a minor stroke. Researchers will scan 40 stroke survivors and 15 healthy older adults at 1, 6, and 12 months after the stroke while they perform a naming task. The goal is to understand w…

This study looks at how stroke changes the way the brain handles walking while doing another task, like listening or navigating. Researchers will monitor brain activity in 50 stroke survivors as they walk on different paths and respond to sounds. The goal is to better understand …

This study aims to validate new guidelines for placing surface EMG electrodes on the calf muscles of people who have had a stroke. Researchers will compare the new EPICA guidelines with standard SENIAM guidelines using ultrasound to see which placement gives more accurate muscle …

This study uses a robotic arm and brain stimulation to learn how different brain areas control reaching movements in people who have had a stroke and those who haven't. Researchers will measure movement paths, speeds, and accuracy. The goal is to understand brain changes after st…

This study follows 180 adults with cerebral small vessel disease to see how their condition changes over time after a stroke. Researchers will use MRI scans and blood tests to track disease progression and look for links to thinking skills, daily function, and stroke recurrence. …

This study is looking at whether a blood test measuring DNA methylation can predict the risk of silent brain injury in elderly patients undergoing TAVR, a minimally invasive heart valve replacement. About 542 people over age 70 with severe aortic stenosis will have their DNA test…

This study is testing three different doses of a non-invasive brain stimulation technique called rTMS in 26 chronic stroke survivors with arm weakness. The goal is to see which dose best boosts brain signals to the hand muscles and improves motor learning. Participants will recei…

This study looks at how changing what stroke survivors see in virtual reality affects their hand movements. 15 chronic stroke survivors and 15 healthy people will do hand exercises in VR while their finger movements and muscle activity are recorded. The goal is to understand how …

This study looks at how people who had a stroke more than 6 months ago learn a new walking pattern using distorted visual feedback. Researchers want to see if a short 5-minute exercise session helps them remember the new walking pattern a day later. 80 participants will be split …

This study looks at whether combining prism adaptation training with electrical stimulation can help people who have had a stroke and have spatial neglect (trouble noticing things on one side). Researchers will measure changes in pointing behavior, brain activity, and walking abi…

This study tests whether a live video call between a neurologist and emergency medical technicians (EMTs) can improve the accuracy of stroke detection in the ambulance. About 512 adults with suspected stroke will take part. The goal is to see if video assistance helps diagnose st…

This study looks at whether new, quick tests that measure how fast people can move can help doctors diagnose brain diseases like Alzheimer's and predict recovery after a stroke. Researchers will test 129 adults aged 40-85 with stroke or memory problems. The goal is to see if thes…

This study tests an 8-week online program that teaches stroke survivors how to start their own business. The goal is to help them find meaningful work and improve their confidence and life satisfaction. The program is for adults aged 18-65 who had a stroke and have been out of pa…

This study looks at sleep problems like sleep apnea and insomnia in 226 people who have had a stroke. Researchers want to see how these sleep issues affect recovery, daily activities, and quality of life. Participants will use a home sleep test and a smartwatch to track sleep and…

This study tests if combining a gentle brain stimulation technique (tDCS) with watching hand movement videos (action observation therapy) can help people who had a stroke regain hand function. 60 adults with chronic stroke will receive 10 sessions of either the combined treatment…

This study explores whether a special MRI technique can help people who have had a stroke improve their reading. Participants will practice controlling their own brain activity using real-time feedback from the MRI scanner. The goal is to retrain the brain's language areas to wor…

This study will video-record occupational therapy sessions for adults recovering from stroke or spinal cord injury. Researchers want to understand exactly what therapists do to help patients improve arm and hand movement. The goal is to create a toolkit that makes rehabilitation …

This study follows 24 people who had a stroke and were recently diagnosed with atrial fibrillation (AF), a heart rhythm problem. Researchers want to see how AF changes over two years by monitoring heart activity, blood markers, and heart structure. The goal is to better understan…

This study tests whether temporarily stimulating a specific part of the brain can improve hand, arm, and speech abilities in people who had a stroke at least 6 months ago. Ten participants will have a thin wire placed deep in the brain for less than 30 days to deliver mild electr…

This study compares two rehabilitation methods to improve finger movement in 40 people who had a stroke. One method encourages using any strategy to reach goals, while the other focuses on improving movement technique. Participants will do 10 days of piano training and have brain…

This study tests whether a new type of exercise that retrains how muscles work together can improve arm function in people who have had a stroke. Researchers will compare this approach to standard strength training in 74 participants. The goal is to see if changing muscle coordin…

This study tests whether a computer model can predict which reading treatment works best for people who developed dyslexia after a stroke. Twelve participants will each try two different therapies—phonomotor treatment and semantic feature analysis—for 60 hours each. The goal is t…

This early study tests whether a brain implant can help people with severe paralysis from conditions like ALS, spinal cord injury, or stroke control devices using their thoughts. The implant records brain signals to decode text or synthesized speech. Only 3 adults will participat…

This study looks at how changes in brain blood flow affect breathing control during sleep in healthy adults. Researchers will expose participants to normal oxygen and low oxygen levels to see how the brain responds. The goal is to better understand sleep apnea and related conditi…

This study explores whether a non-invasive brain-computer interface (BCI) can help people with motor disorders, such as spinal cord injury or stroke, control assistive devices using their thoughts. Researchers will record brain signals with EEG and use machine learning to interpr…

This study looks at how shoulder pain on the paralyzed side after a stroke affects arm movement, trunk control, fear of falling, mobility, and independence. Researchers will assess 62 stroke survivors using standard tests and ultrasound. The goal is to better understand the relat…

This pilot study looks at how botulinum toxin (Botox) injections affect the muscles, tendons, and nerves in the feet of people who have had a stroke and developed a tight, twisted foot (equinovarus). Researchers will use special ultrasound and movement tests to track these change…

This study looks at how the brain talks to muscles in people who have had a stroke. Researchers will use gentle, non-invasive brain stimulation and measure brain and muscle activity while participants squeeze a device with their weak hand. The goal is to see if this stimulation c…

This study aims to understand how the brain responds to magnetic stimulation when it is timed with natural brain waves. Researchers will test healthy adults and people who had a stroke at least 6 months ago. The goal is to find ways to make brain stimulation more effective for im…

This study tests whether a mild electrical current applied to the ear can help the brain learn and control hand movements. Researchers want to understand how this stimulation affects brain chemicals that support learning. The study involves 110 adults, including some who have had…

This study is testing a special glove equipped with sensors to measure how well stroke survivors can feel touch. The glove is part of a larger robotic rehabilitation program aimed at improving both movement and thinking skills. Researchers will enroll 126 people who had a stroke …

This study looks at how swelling around a brain bleed affects recovery in 500 stroke patients. Researchers will use MRI scans and blood tests to understand the swelling's role. The goal is to find new ways to treat this devastating type of stroke.

This study looks at up to 100 young adults (ages 18-55) who have had a stroke to understand how they recover. Researchers will collect detailed health information and samples to see what factors like age, lifestyle, and biology affect recovery. The goal is to test if this detaile…

This study will track how often and how intensely patients with moderate to severe brain injury are moved or exercised while in intensive care units in Scandinavia. Researchers want to see if more movement is linked to better outcomes and safety. About 198 adults on breathing mac…

This study looks at whether a fast genetic test can help doctors pick the best blood-thinning medication for people who have had a minor stroke or a high-risk mini-stroke (TIA). The test checks a gene called CYP2C19, which affects how the body processes certain antiplatelet drugs…

This study tests a new, lightweight ultrasound device called NeoDoppler that can be gently placed on a newborn's soft spot (fontanelle) to continuously measure blood flow in the brain. Researchers will enroll 180 preterm and full-term infants, including those with conditions like…

This study looks at whether low magnesium in the blood is linked to memory, attention, and other thinking problems after a stroke. Researchers will measure magnesium levels and give cognitive tests to 80 stroke patients over several weeks. The goal is to understand if magnesium d…

This study is creating a biological bank of blood samples from 1,000 people with atrial fibrillation (AF) and stroke. Researchers will collect DNA and plasma to study the genetic roots of these conditions. The goal is to better understand why AF leads to stroke and find new drug …

This study tests whether a gentle electrical current applied to the brain (tACS) can improve hand movement in people who had a stroke more than 6 months ago. Researchers will use brain scans and EEG to see how the stimulation changes brain activity. 45 participants (including hea…

This study follows 100 stroke survivors with arm weakness to see how their own sense of arm use changes during intensive rehab. Researchers compare patients' perceptions with actual arm function using standard tests. The goal is to better understand the gap between what patients …

This study looks at whether people who have a blood clot in the lungs (pulmonary embolism) are more likely to have a stroke if they also have a small hole in their heart (called a PFO). About 1 in 4 people have this hole, which can let a clot travel to the brain. Researchers will…

This study looks at how the brains of 25 stroke patients with weak hand muscles activate during mirror movement therapy. Researchers use a special brain scanner to measure activity. The goal is to understand brain changes, not to test a treatment.

This study tests whether speech therapy delivered via video call works as well as traditional in-clinic therapy for people with aphasia, a language disorder caused by stroke. One hundred adults who had a stroke at least a year ago will receive either remote or in-person therapy. …

This study tests a new camera tool that watches how stroke survivors move their arms during robot-assisted therapy and gives feedback. The goal is to see if group therapy sessions (up to 3 people) work as well as one-on-one sessions. About 42 adults who had a stroke 6 months to 6…

This study looks for brain signals that can track how well stroke patients recover their ability to walk. Researchers will use a mobile brain scanner while patients walk with a robotic device. The goal is to find markers that could help doctors personalize therapy and predict rec…

This early study tests whether a non-invasive device that gently stimulates a nerve in the ear (taVNS) can change brain activity and genetic markers in people who recently had a stroke. Forty-four participants with arm weakness will receive either real or sham stimulation. Resear…

This small study tests a smartphone app that creates a 'digital twin' of the patient to help manage health after a stroke, moyamoya disease, or cerebral amyloid angiopathy. Twenty adults will either use the app plus standard care, or standard care alone. The goal is to see if pat…

This study looks at adults with serious brain injuries from stroke, trauma, or bleeding who need a breathing machine. Researchers want to see if certain machine settings are linked to how severe the brain injury is. About 19 people will take part, and no new treatments are being …

This study tests a new virtual reality (VR) system built into a walking robot to help stroke survivors use their weaker leg more during walking. 30 people (15 stroke survivors and 15 healthy adults) will try a single session of VR-guided walking. The goal is to see if real-time v…

This study tests a new walking training method for people who have had a stroke. It combines treadmill walking with resistance and real-time feedback to help improve leg strength and walking symmetry. The study includes 15 stroke survivors and 15 healthy adults, each attending a …

This study is looking for 250 stroke survivors to understand why many feel overwhelming tiredness after a stroke, known as post-stroke fatigue. Researchers will measure heart rate variability, heart function, and blood markers to see if problems with the autonomic nervous system …

This study is looking for biological clues to explain why some stroke survivors improve their walking with high-intensity interval training (HIIT) while others do not. Researchers will measure blood lactate, brain chemicals, and blood flow in 55 veterans with chronic stroke. The …

This study tests a new way to measure walking efficiency in people who have had a stroke. Researchers will have 18 participants walk on a treadmill, including a resisted walking trial, to see if a biomechanical measure can pinpoint movement problems better than current methods. T…

This study checks if a hand laterality task can help measure recovery in 30 stroke survivors. Participants will identify whether images show a right or left hand. The goal is to see if this task is a valid tool for assessing brain function after a stroke.

This study looks at how using arm support (like a cane or parallel bars) changes walking patterns in people who have had a stroke. Thirty-four participants will walk on a special treadmill under three conditions: no support, one-arm support, and two-arm support. The goal is to se…

This study follows 252 adults with muscle, bone, or joint problems (like arthritis, back pain, or after surgery) to see how well they do their prescribed home exercises. Researchers will track who sticks with the program and why, looking at factors like pain, mood, and support. T…

This study is collecting movement, activity, and genetic data from 70 stroke patients to create digital twins—virtual models that reflect each patient's recovery patterns. The goal is to develop a tool that predicts how well someone will recover after a stroke. No treatments or d…

This study looks at a specific layer of tissue in the lower back (thoracolumbar fascia) in people who had a stroke at least six months ago. Researchers will measure its thickness using ultrasound and see if it relates to balance, trunk control, flexibility, and daily independence…

This study tests whether virtual reality (VR) training can help people recovering from a stroke improve their walking skills. Forty participants will practice community walking tasks in a virtual environment for 4 weeks. The main goal is to see if this approach is feasible and ac…

This study looks at how a single session of cardiovascular exercise affects pain sensitivity in people who have had a stroke and in healthy individuals. Researchers will measure pain thresholds before and after exercise in 60 participants. The goal is to understand why exercise c…

This study investigates how brain activity changes when people imagine moving their wrist. Researchers will use advanced brain scans (MRI and MEG) to create personalized models of these signals, then test if they can decode imagined movements using simpler EEG recordings. The goa…

This study follows 400 stroke patients in rehabilitation units to understand how walking and balance improve during the first six months after a stroke. Researchers will measure walking ability and balance using simple tests. The goal is to better predict recovery and guide thera…

This study tracks 350 stroke patients across the Asia-Pacific to see how well a proven clot-removal procedure (endovascular thrombectomy) works in everyday hospitals, not just in controlled trials. Researchers will analyze patient outcomes, imaging, and even the removed clots to …

This study examines the role of the plantaris, a small calf muscle, in children having surgery for tight ankles (equinus). Researchers will randomly change the order of tendon cuts during surgery to measure how much each contributes to ankle movement. The goal is to understand if…

This study looks at how the brain recovers arm movement after a stroke. Researchers will study 50 people who had a stroke 3 to 6 months ago and have trouble moving their arm. Some will get 30 hours of special arm therapy over 6 weeks, while others get usual care. The goal is to l…

This study explores how targeted brain stimulation can improve movement speed in people who have had a stroke. Researchers will first test the technique in 60 healthy volunteers, then in 20 stroke patients. The goal is to understand which brain areas control action speed and whet…

This study compares a new, data-driven method for emergency responders to decide which hospital to take a stroke patient to, versus the current standard method. The goal is to see if the new approach helps rural patients get to a hospital that can perform specialized clot-removal…

This study looks at whether paying attention to an outside target (external focus) or to your own body movements (internal focus) helps people who had a stroke stand up from a chair more evenly. Twenty adults who had a stroke at least six months ago will try both approaches. The …

This study tests whether gentle muscle vibrations can help the brain form new connections after a stroke or traumatic brain injury. Researchers will measure brain and spinal cord activity in 56 participants before, during, and after a 5-week vibration treatment. The goal is to un…

This study investigates whether brain surface recordings can decode Mandarin Chinese speech, including tones, from imagined speech. About 50 participants with brain tumors or epilepsy will have temporary electrodes placed during surgery, and 10 people with severe speech loss will…

This study follows 150 people who recently had a stroke to see how their walking ability recovers over time. Researchers will measure walking speed and distance, and test if specific therapies can improve recovery. The goal is to create better rules for predicting and enhancing r…

This study looks at how the diaphragm (the main breathing muscle) changes shape and moves in people who have had a stroke and have weakness on one side of the body. Researchers will measure diaphragm thickness and movement using ultrasound and compare it to breathing muscle stren…

This study is collecting information from 200 people with cerebral palsy, multiple sclerosis, stroke, fibromyalgia, or similar nerve disorders to see how the EXOPULSE Suit affects their balance and risk of falling over time. Participants will be followed routinely, and researcher…

This study aims to understand if COVID-19 vaccines have any impact on brain health in healthy people. Researchers will use MRI scans to look for changes in the brain's blood vessels and structure. The study will follow 500 adults from Hong Kong who have already had a baseline bra…

This study looks at 100 stroke survivors with shoulder pain to see if ultrasound images of the shoulder can predict how much pain they feel. Researchers will compare ultrasound findings with pain scores at rest, during movement, and at night. The goal is to better understand the …

This long-term study is tracking 5,000 adults in Hong Kong who either have a brain disease (like stroke or dementia) or are at high risk due to family history or early signs. Researchers will collect medical records and questionnaires every 6 months to find what factors lead to b…

This study is looking back at medical records of 2,600 stroke patients who received clot-busting drugs between 4.5 and 24 hours after their stroke started. The goal is to see if giving the drug later than the usual 4.5-hour window can still lead to good recovery. The study does n…

This study is testing a new device that aims to measure pressure inside the skull from the outside, avoiding the need for surgery. Currently, doctors must drill a hole in the skull to monitor intracranial pressure (ICP) in patients with conditions like traumatic brain injury or s…

This study tests whether delivering transcranial magnetic stimulation (TMS) at the exact moment your brain shows strong signals to your hand muscles can improve hand function after a stroke. Researchers will compare this personalized timing to random timing in 37 people who had a…

This study looks at people with cerebral small vessel disease, a common condition in older adults that can lead to stroke and dementia. Researchers will measure brain activity using EEG and test whether home-based cognitive training or mild brain stimulation can improve thinking …

This study explores whether a training program that mixes cognitive tasks (like memory and attention exercises) with physical therapy can improve recovery in people with post-stroke cognitive impairment or Moyamoya disease. Researchers will also use brain imaging to see how think…

After a stroke, many people struggle to use both hands together. This study checks if a new test called the Ad-AHA Stroke accurately measures how people actually use their hands in daily life. Thirty-two stroke survivors will wear wrist sensors for three days while their hand use…

This study is following 500 people with cerebral small vessel disease (CSVD) to see how their genes affect their brain scans, symptoms, and health over time. Participants get genetic testing and MRI scans at the start and again after 1-2 years. The goal is to better understand th…

This study looks at whether combining two types of attention-focus instructions (internal and external) in the same session helps stroke survivors improve arm function more than using them one after the other. It involves 36 adults who had a stroke within the past 6 months. The g…

This study is testing whether a special heart MRI can measure scarring in the left atrium, which might lead to atrial fibrillation. Researchers will enroll 100 people who had a stroke with no clear cause and who are already scheduled to get an implantable heart monitor. The goal …

This study is testing whether sending a portable ECG monitor to people with elevated NT-proBNP (a heart stress marker) can catch hidden atrial fibrillation and reduce strokes. 4,000 adults aged 40+ without known AF will be randomly assigned to either 7 days of home monitoring or …

This study is looking at whether certain gene changes (variants) in a protein called annexin A2 are linked to strokes that happen for no clear reason, especially in younger adults. Researchers will compare blood samples from 240 people who have had a stroke with no known cause. T…

This study uses powerful 3T and 7T MRI scanners to create detailed maps of brain activity and connections in 100 stroke patients and 10 healthy volunteers. The goal is to understand how the brain reorganizes after a stroke and to identify patterns linked to motor deficits. Findin…

This early study is testing whether a robot can help doctors perform delicate brain blood vessel procedures, such as angiography, embolization, and thrombectomy. Ten patients scheduled for these standard procedures will have them done using a robotic system instead. The main goal…

This study tests whether combining non-invasive brain and spinal cord stimulation during a movement task can improve hand function and thinking in people with stroke or spinal cord injury. 45 participants will receive both types of stimulation separately and together to see if th…

This study is testing whether a non-invasive ultrasound scan, combined with artificial intelligence (AI), can quickly identify bleeding in the brain (intracerebral hemorrhage) in people having a stroke. Researchers will enroll 500 adults with acute stroke and perform a standard C…

This study will track 10,000 adults who receive tenecteplase for a stroke caused by a blood clot. Researchers want to see how well patients recover and if there are any safety issues when the drug is used in everyday hospital care. The goal is to improve stroke treatment across C…

This study is testing whether wearable sensors can track how well people recover from a stroke during inpatient rehabilitation. Researchers will place small, non-invasive sensors on the body to continuously collect movement data. The goal is to see if this data can predict how we…

This study is a registry that gathers medical information from up to 40,000 people who have had surgery for stroke, brain aneurysm, or other brain blood vessel problems. Researchers will look at this data to find patterns that help predict recovery and compare different treatment…

This study tests different power levels and timing of low-intensity focused ultrasound (LIFUS) to see which best improves arm movement and motor learning in stroke survivors. 24 adults who had a stroke at least 6 months ago and have arm weakness will participate. The goal is to f…

This study is testing a new questionnaire called the Pressure Relief Frequency Scale (PReFS) to see if it can reliably help wheelchair users with neurologic disorders (like spinal cord injury, stroke, or traumatic brain injury) decide how often they need to relieve pressure to pr…

This study aims to learn how the brain and spinal cord change after a stroke. Researchers will use MRI scans to compare stroke patients with healthy volunteers. The goal is to find patterns that predict recovery and understand why symptoms vary. The study does not test a treatmen…

This study looks at data from the HeartMate 3 heart pump to see if it can help predict problems like bleeding, infection, or frailty in people with advanced heart failure. Researchers will track 150 adults getting the pump and compare pump alarms and readings to their health over…

This study follows 213 adults recovering from a first ischemic stroke to see if the intensity of inpatient rehabilitation (high vs. moderate) affects their functional recovery at six months. It also compares people whose stroke was linked to atrial fibrillation with those whose s…

This study looks at why people who have had a stroke often have trouble coordinating their legs when walking. Researchers will measure brain and nerve signals in 50 participants to find out what causes these coordination problems. They will also test if a mild electrical stimulat…

This study follows 140 working-age stroke survivors in France to find out what factors help or hinder their return to work. Researchers will look at medical details, personal beliefs, and job-related issues. The goal is to create better support plans for people recovering from a …

This study is testing a new PET scan tracer called 18F-GP1 that sticks to activated platelets in blood clots. Researchers will scan 120 adults who recently had an ischemic stroke to see if they can find where clots are coming from. The goal is to better understand different types…

This study explores whether a new system using ultrasound and light sensors can remotely monitor brain blood flow in people who have had a stroke. Researchers will test the technology in 140 participants, including healthy older adults and those with stroke, dementia, depression,…

This study is testing a new wearable patch that uses a microphone to listen to swallowing sounds in people who have trouble swallowing after a stroke. The patch is placed on the neck and records sounds during a standard swallowing X-ray test. Researchers will use machine learning…

This study looks at how fear of movement (kinesiophobia) affects balance and confidence in stroke patients. Researchers will survey 138 stroke survivors using questionnaires about fear, balance, pain, and mood. No treatments are given—the goal is simply to understand the connecti…

This study will follow 500 people who have had a stroke and also have atrial fibrillation (an irregular heartbeat). Some were taking blood thinners when they had their stroke, others were not. Researchers want to understand why blood thinners fail in some patients, by looking at …

This study checks if a pressure-sensitive insole (Ceriter Stride One) can accurately measure walking patterns in people with stroke, brain injury, or spinal cord injury. About 30 participants will wear the insole while walking on a high-tech treadmill (GRAIL) to compare results. …

This study looks at how stroke changes the way people move their arms when walking. Researchers will measure brain activity and muscle patterns in 84 people (some who had a stroke and some healthy) while they walk on a treadmill. The goal is to understand why arm swing is often a…

This study tests a high-resolution imaging system to see tiny structures in the eye that routine tools cannot detect. Researchers will scan 1,200 people with various eye conditions and healthy volunteers. The goal is to better understand diseases like glaucoma, diabetes, and reti…

This study looks at how often fatigue occurs in people who have had their first stroke and what factors might make it worse. Researchers will measure fatigue using simple questionnaires and also check things like pain, mood, sleep, and physical ability. The goal is to better unde…

This study looks at how deep brain stimulation (DBS) changes movement in people with conditions like Parkinson's disease or essential tremor. About 60 people scheduled for DBS surgery will have extra temporary electrodes placed on the brain to measure muscle activity during stimu…

This study looks at how memory and thinking problems after a stroke affect a person's ability to relearn walking. Researchers will use walking tests, brain scans, and thinking assessments in 65 older adults who had a stroke at least six months ago. The goal is to understand which…

This study looks at how genes and brain scans can help predict recovery from aphasia, a language disorder that often follows a stroke. Researchers will enroll 90 adults aged 40-90 who have had a stroke and have trouble speaking or understanding language. By understanding these bi…

This study aims to see if brain scans and a technique called transcranial magnetic stimulation (TMS) can predict how well someone will recover arm movement after a stroke. Researchers will collect data from 657 adults who recently had a stroke and have arm weakness. The goal is t…

This study looks at how stroke survivors' arm muscles respond when they imagine or watch movements. Researchers measure tiny muscle signals in the wrist and fingers during these mental exercises. The goal is to understand which techniques best help the brain relearn movement afte…

This study looks at how hospitals in Villavicencio, Colombia, manage stroke cases by reviewing patient records. Researchers want to find delays in treatment and see if doctors follow best-practice guidelines. About 100 adults diagnosed with stroke will be included. No new treatme…

This study monitors how stroke survivors use their arms during everyday activities outside the clinic. Researchers will track hand movements, joint range, and wrist distance using wearable sensors. The goal is to connect real-world movement patterns with standard recovery tests l…

This study uses fMRI to look at brain and spinal cord activity in people who have had a stroke and have weakness on one side. Participants will perform a simple shoulder movement while being scanned. The goal is to understand which neural pathways are used for movement after a st…

This study is building a large registry of people who have had a stroke and still have symptoms. The goal is to connect them with researchers studying new ways to improve recovery. No treatments or tests are given—just observation and data collection.

This pilot study tests better ways to recruit a wider range of people into stroke rehabilitation research, especially women and those with aphasia (trouble speaking or understanding language). Researchers will compare a new, more supportive recruitment approach to the usual metho…

This study looks at why leg muscles tire faster after a stroke and whether a simple procedure called ischemic conditioning can help. Researchers will measure blood flow and muscle fatigue in 40 stroke survivors. The goal is to understand how blood flow affects muscle endurance an…

This study looks at whether a gentle brain stimulation technique called anodal tDCS can improve how people learn stepping movements. Researchers will test this in both healthy adults and chronic stroke survivors. Participants will receive either real stimulation, a sham (fake) st…

This study follows 130 patients with disorders of consciousness after stroke, traumatic brain injury, or oxygen deprivation. Researchers will use brain scans, electrical tests, and regular check-ups to find factors that might predict if and when patients regain consciousness. The…

This study looks at whether placebos—given openly or hidden—can change brain activity and improve movement in people who had a stroke at least six months ago. Researchers will use brain scans and motor tests to measure effects. The goal is to understand how placebos work in the b…

This study looks at how taking multiple medications (polypharmacy) affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older over two years to understand their medicati…

This study will follow 5,000 people who receive newer endovascular devices (like coils, stents, or flow diverters) to treat a brain aneurysm. Researchers want to see how often the aneurysm comes back and what factors, such as smoking, might play a role. The goal is to improve saf…

This study is tracking 1,000 adults with psoriasis to see how their skin condition relates to heart disease. Researchers will use blood tests and heart imaging to find early signs of heart problems. The goal is to better understand why people with psoriasis have higher rates of h…

This study follows 120 stroke survivors for six months, using brain scans and movement tests to understand why some people develop arm stiffness and weakness. Researchers hope to find early signs that predict recovery, which could guide future rehabilitation. Participants must ha…

This study will measure a protein called BD-tau in the blood of 100 people who have had an acute ischemic stroke. Researchers will take blood samples every hour for 48 hours to see how the protein levels change over time. The goal is to better understand brain injury patterns and…

This study watches how the body uses energy in people recovering from stroke, brain injury, or major surgery. Researchers will measure things like metabolism, sleep, walking, and brain activity in 80 adults. The goal is to build computer models that predict each person's energy n…