Can a clot-busting procedure help stroke patients with prior disabilities?
NCT ID NCT05911568
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether removing a large blood clot from the brain (endovascular thrombectomy) is better than standard medical care for stroke patients who already had a moderate-to-severe disability before their stroke. About 1,060 adults with a recent stroke and a pre-existing disability will be randomly assigned to either get the clot removal procedure or not. The goal is to see which approach leads to better recovery or survival.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Baptist Memorial Hospital
RECRUITINGMemphis, Tennessee, 38120, United States
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Barnes Jewish Hospital
RECRUITINGSaint Loius, Missouri, 63110, United States
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Boston Medical Center
RECRUITINGBoston, Massachusetts, 02118, United States
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Columbia University
RECRUITINGNew York, New York, 10032, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Hartford Health Hospital
RECRUITINGHartford, Connecticut, 06106, United States
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HonorHealth
RECRUITINGPhoenix, Arizona, 85013, United States
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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Kaiser Permanente Los Angeles Medical Center
RECRUITINGLos Angeles, California, 90027, United States
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New York University
RECRUITINGBrooklyn, New York, 11220, United States
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Providence St. Vincent Medical Center
RECRUITINGPortland, Oregon, 97225, United States
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Standford
RECRUITINGPalo Alto, California, 94305, United States
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Swedish Medical Center
RECRUITINGEnglewood, Colorado, 80113, United States
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University of California at Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Cincinnati Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
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University of Cincinnati San Diego
RECRUITINGSan Diego, California, 92121, United States
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University of Louisville
RECRUITINGLouisville, Kentucky, 40202, United States
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University of Miami
RECRUITINGMiami, Florida, 33125, United States
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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University of Texas at Austin
RECRUITINGAustin, Texas, 78712, United States
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University of Washington
RECRUITINGSeattle, Washington, 98104, United States
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
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West Virginia University
RECRUITINGMorgantown, West Virginia, 26506, United States
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Yale University
RECRUITINGNew Haven, Connecticut, 06510, United States
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