Eye ultrasound could speed up brain swelling detection

NCT ID NCT07332234

Recruiting now Diagnosis Sponsor: Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș" Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a simple ultrasound of the optic nerve can quickly detect brain swelling and inflammation in ICU patients with conditions like meningitis, encephalitis, or stroke. Researchers will measure the optic nerve sheath diameter in 200 adults and compare it with standard tests. If accurate, this painless, low-cost method could help doctors make faster treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Optic nerve sheath diameter measurement via ultrasound
What this could lead to: If successful, this could provide a quick, safe, and low-cost bedside tool to detect brain swelling and inflammation, helping doctors make faster treatment decisions.
What could go wrong: This is an early diagnostic study, not a treatment trial. The ultrasound method may not be accurate enough to replace current standard tests, and results may vary by patient condition.

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Conditions

The condition(s) this trial relates to.

brain neoplasm encephalitis intracranial hypertension meningitis meningoencephalitis neoplasm of cerebral hemisphere stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL TUMORS INTRACRANIAL HYPERTENSION MENINGITIS MENINGITIS/ENCEPHALITIS STROKE ULTRASOUND

Contacts and locations

Locations

"Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical Diseases
RECRUITING

Bucharest, Bucharest, 030303, Romania
Fundeni Clinical Institute
RECRUITING

Bucharest, Bucharest, 022315, Romania

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