Acupuncture meets brain zaps: new combo aims to restore movement after stroke
NCT ID NCT07113990
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether combining electroacupuncture (mild electric pulses through thin needles) with repetitive transcranial magnetic stimulation (rTMS, a non-invasive brain stimulation) can improve arm and leg movement after a stroke. 180 adults who had their first stroke within the last 2 weeks to 6 months will receive either real or sham electroacupuncture alongside rTMS. Researchers will measure changes in motor function using standard movement tests and brain scans.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- electroacupuncture and repetitive Transcranial Magnetic Stimulation (rTMS)
- What this could lead to
- If it works, this could offer a new, non-drug way to help people regain movement after a stroke.
- What could go wrong
- This is a mid-sized trial, and the sham control may show similar results. The effect may be modest and not apply to all stroke survivors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with stroke confirmed by neuroimaging (CT/MRI). * First-ever stroke, unilateral hemispheric lesion, related to motor dysfunction. * Age between 40 and 75 years. * Duration from stroke onset between 2 weeks and 6 months. * Brunnstrom stage II-IV. * Right-handed. * Able to understand instructions and voluntarily provide written informed consent. Exclusion Criteria: * History of epilepsy or familial epilepsy. * Motor dysfunction due to non-vascular causes (e.g., tumor, trauma). * Severe aphasia or cognitive impairment (MoCA \< 18). * Severe systemic complications (e.g., severe organ dysfunction, deep vein thrombosis). * Presence of metallic implants or contraindications for MRI. * Severe anxiety (HAMA \> 7) or depression (HAMD \> 8). * Severe spasticity (modified Ashworth ≥ 2). * Fear or intolerance of TMS or electroacupuncture. * Pregnancy, breastfeeding, or concurrent participation in other clinical trials affecting outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fujian Provincial People's Hospital
NOT_YET_RECRUITINGFuzhou, Fujian, 350004, China
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Fuzhou University Affiliated Provincial Hospital
RECRUITINGFuzhou, Fujian, 350001, China
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Wenzhou Hospital of Traditional Chinese Medicine
NOT_YET_RECRUITINGWenzhou, Zhejiang, 325000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Effects of transcranial direct current stimulation and pelvic proprioceptive neuromuscular facilitation on trunk control, balance and functional mobility in stroke patients
- Correlation of visual and motor deficits in stroke patients
- Pilot study on the effects induced by an electromyographic-controlled functional electrical stimulator (FitFES) for upper limb rehabilitation in post-stroke patients
- Brazilian version of a behavior change intervention to support healthy lifestyle adoption after stroke - iVIDAVC: protocol for a pilot randomized study
- Determination of efficacy of sustained motor contraction generated using StimWave peripheral nerve stimulator
- Can a PET tracer reveal hidden brain inflammation?