New hope for bleeding stroke: can clevidipine save brains?

NCT ID NCT06402968

Recruiting now Disease control Sponsor: Zeenat Qureshi Stroke Institute Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 10 times

Summary

This study tests whether the drug clevidipine can lower blood pressure quickly and steadily in people having a bleeding stroke (intracerebral hemorrhage). High blood pressure can make the bleeding worse, so getting it under control fast is critical. The trial will compare clevidipine to other standard blood pressure treatments in 1,000 adults, measuring how many reach a safe blood pressure target within one hour.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Clevidipine (an intravenous blood pressure medication)
What this could lead to: If successful, this could provide a faster, more reliable way to control blood pressure during a bleeding stroke, potentially reducing brain damage and improving recovery.
What could go wrong: This is a Phase 4 trial, but the benefit over existing treatments is unproven. The drug may cause side effects like low blood pressure or heart rhythm issues, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder intracerebral hemorrhage stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION INTRACEREBRAL HEMORRHAGE STROKE

Contacts and locations

Locations

Albany Medical Center
RECRUITING

Albany, New York, 12208, United States
Antelope Valley Medical Center
RECRUITING

Lancaster, California, 93534, United States
Augusta University-Neuroscience Center
RECRUITING

Augusta, Georgia, 30912, United States
CentraCare - St. Cloud Hospital
RECRUITING

Saint Cloud, Minnesota, 56303, United States
Cleveland Clinic Akron General
RECRUITING

Akron, Ohio, 44307, United States
Cleveland Clinic Florida
RECRUITING

Weston, Florida, 33331, United States
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195, United States
Cleveland Clinic Martin North Hospital
RECRUITING

Stuart, Florida, 34994, United States
Community Hospital
RECRUITING

Munster, Indiana, 46321, United States
Frederick Memorial Hospital
RECRUITING

Frederick, Maryland, 21701, United States
Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States
ProMedica Toledo Hospital
RECRUITING

Toledo, Ohio, 43606, United States
Stanford Medical Center (Stanford Health Care)
RECRUITING

Palo Alto, California, 94304, United States
UT Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
University of California
RECRUITING

Irvine, California, 92696-7600, United States
University of Michigan Health-West
RECRUITING

Wyoming, Michigan, 49519, United States
University of Missouri
RECRUITING

Columbia, Missouri, 65212, United States
University of South Florida
RECRUITING

Tampa, Florida, 33606, United States
University of Texas Health Science Center San Antonio
RECRUITING

San Antonio, Texas, 78229, United States
Wellstar Kennestone Regional Medical Center
RECRUITING

Marietta, Georgia, 30060, United States

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