New hope for bleeding stroke: can clevidipine save brains?

NCT ID NCT06402968

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether the drug clevidipine can lower blood pressure quickly and steadily in people having a bleeding stroke (intracerebral hemorrhage). High blood pressure can make the bleeding worse, so getting it under control fast is critical. The trial will compare clevidipine to other standard blood pressure treatments in 1,000 adults, measuring how many reach a safe blood pressure target within one hour.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Clevidipine (an intravenous blood pressure medication)

What this could lead to

If successful, this could provide a faster, more reliable way to control blood pressure during a bleeding stroke, potentially reducing brain damage and improving recovery.

What could go wrong

This is a Phase 4 trial, but the benefit over existing treatments is unproven. The drug may cause side effects like low blood pressure or heart rhythm issues, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder intracerebral hemorrhage stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Albany Medical Center

    RECRUITING

    Albany, New York, 12208, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Antelope Valley Medical Center

    RECRUITING

    Lancaster, California, 93534, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Augusta University-Neuroscience Center

    RECRUITING

    Augusta, Georgia, 30912, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CentraCare - St. Cloud Hospital

    RECRUITING

    Saint Cloud, Minnesota, 56303, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic Florida

    RECRUITING

    Weston, Florida, 33331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cleveland Clinic Martin North Hospital

    RECRUITING

    Stuart, Florida, 34994, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • ProMedica Toledo Hospital

    RECRUITING

    Toledo, Ohio, 43606, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Stanford Medical Center (Stanford Health Care)

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California

    RECRUITING

    Irvine, California, 92696-7600, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan Health-West

    RECRUITING

    Wyoming, Michigan, 49519, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Missouri

    RECRUITING

    Columbia, Missouri, 65212, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of South Florida

    RECRUITING

    Tampa, Florida, 33606, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Health Science Center San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••