Can a few short nights of sleep tip the scales toward high blood pressure?

NCT ID NCT06482814

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study looks at how partial sleep deprivation affects blood pressure in healthy young adults whose parents have high blood pressure compared to those whose parents have normal blood pressure. Participants will spend 10 days in a sleep lab, with some nights allowing only 5 hours of sleep and others allowing 9 hours. Researchers will measure blood pressure around the clock to see if a family history of hypertension makes the body more sensitive to the effects of short sleep.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Partial sleep deprivation (sleep restriction) versus normal sleep
What this could lead to
If short sleep raises blood pressure more in those with a family history of hypertension, it could point to sleep as a key target for preventing high blood pressure in at-risk people.
What could go wrong
This is a small, early-stage study in healthy young adults, so results may not apply to the general population. The effects of a few nights of restricted sleep may not reflect long-term sleep patterns.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

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