Stroke recovery gets a boost: modified cardiac rehab targets body and mind

NCT ID NCT07039305

Recruiting now Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a modified cardiac rehabilitation program—combining aerobic and strength exercises—can improve physical function and reduce depression in people who had a stroke at least six months ago. Researchers will enroll 76 participants, some with depression and some without, to see if the program helps with walking distance, daily activities, and mood. The goal is to offer a new, practical therapy for common post-stroke problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: modified cardiac rehabilitation program (aerobic and resistance exercise training)
What this could lead to: If successful, this program could become a new standard therapy to improve walking ability, mood, and daily function in people who have had a stroke.
What could go wrong: This is a small early-stage study with only 76 participants, so results may not apply to all stroke survivors. The exercise program may be too demanding for some, and depression could limit how much people benefit.

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Conditions

The condition(s) this trial relates to.

Depression Motor Activity stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-STROKE DEPRESSION STROKE

Contacts and locations

Locations

Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States

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