Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could stroke patients on blood thinners finally get clot-busting treatment?

NCT ID NCT06878066

Recruiting now Disease control Sponsor: Guri Hagberg Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether clot-busting drugs (alteplase or tenecteplase) are safe and effective for stroke patients who have taken a blood thinner (FXa inhibitor) in the last 48 hours. Current guidelines avoid this treatment due to bleeding concerns, but new evidence suggests it may be safe. The trial will compare 300 patients who receive the clot-buster with those who get standard care, measuring recovery and bleeding risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Alteplase or Tenecteplase (clot-busting drugs)
What this could lead to
If successful, this could change stroke treatment guidelines so that more patients on blood thinners can receive life-saving clot-busting therapy without delay.
What could go wrong
This is a phase 3 trial, but results may not apply to all patients. There is a risk of brain bleeding, and the study does not require a blood test to measure drug levels before treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE ISCHEMIC STROKE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

hemorrhagic stroke intracerebral hemorrhage Intracranial Hemorrhages ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE ANTICOAGULANT THERAPY BLEEDING IN THE BRAIN FACTOR XA INHIBITOR HEMORRHAGIC TRANSFORMATION DUE TO ACUTE STROKE INTRACRANIAL HEMORRHAGES ISCHEMIC STROKE STROKE STROKE (IN PATIENTS WITH ATRIAL FIBRILLATION)

Contacts and locations

Locations

  • Dept of Medicine, Haraldsplass deaconal Hospital

    RECRUITING

    Bergen, 5009, Norway

  • Dept of Medicine, Helse More and Romsdal Health Trust, Aalesund Hospital

    RECRUITING

    Ålesund, 6017, Norway

  • Dept of Neurology, Drammen Hospital Trust

    RECRUITING

    Drammen, 3004, Norway

  • Dept of Neurology, Hospital of Southern Norway, SSHF

    RECRUITING

    Kristiansand, 4615, Norway

  • Dept of Neurology, Innlandet Hospital Trust, Lillehammer

    RECRUITING

    Lillehammer, 2609, Norway

  • Dept of Neurology, Ostfold Hospital Trust, Kalnes

    RECRUITING

    Grålum, 1714, Norway

  • Dept of Neurology, Stavanger University Hospital

    RECRUITING

    Stavanger, 4011, Norway

  • Dept of Neurology, Vesfold Hospital Trust, Tonsberg

    RECRUITING

    Tønsberg, 3103, Norway

  • Dept. Of Medicine, St.Olav Hospital, Trondheim

    RECRUITING

    Trondheim, 7030, Norway

  • Dept. Of Neurology, Haukeland University Hopsital

    RECRUITING

    Bergen, 5009, Norway

  • Dept. of Medicine, Baerum Hospital

    RECRUITING

    Bærum, Gjettum, 1346, Norway

  • Dept. of Neurology, Oslo University Hospital

    RECRUITING

    Oslo, 0450, Norway

  • Dept. of Neurology, Tromso University Hospital

    RECRUITING

    Tromsø, 9019, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.