ANTICOAGULANT THERAPY
Clinical trials for ANTICOAGULANT THERAPY explained in plain language.
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Pilot study tests safer blood thinner options for pregnant women with mechanical heart valves
Disease control Recruiting nowThis pilot study looks at pregnant women with mechanical heart valves to see if using low molecular weight heparin (LMWH) plus low dose aspirin works as well as the standard blood thinner warfarin to prevent dangerous clots around the valve. The study will check if it is possible…
Matched conditions: ANTICOAGULANT THERAPY
Phase: NA • Sponsor: Mount Sinai Hospital, Canada • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New device seals Stroke-Causing heart pouch during bypass surgery
Disease control Recruiting nowThis study tests a device called AtriLASH that closes a small heart pouch (the left atrial appendage) during planned heart surgery in 200 people with atrial fibrillation. The goal is to prevent blood clots that cause strokes, potentially reducing the need for blood-thinning medic…
Matched conditions: ANTICOAGULANT THERAPY
Phase: NA • Sponsor: Institute of Cardiovascular Diseases, Vojvodina • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Could stroke patients on blood thinners finally get clot-busting treatment?
Disease control Recruiting nowThis study tests whether clot-busting drugs (alteplase or tenecteplase) are safe and effective for stroke patients who have taken a blood thinner (FXa inhibitor) in the last 48 hours. Current guidelines avoid this treatment due to bleeding concerns, but new evidence suggests it m…
Matched conditions: ANTICOAGULANT THERAPY
Phase: PHASE3 • Sponsor: Guri Hagberg • Aim: Disease control
Last updated Jun 26, 2026 13:12 UTC
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Vitamin k may let blood thinner users skip Pre-Surgery drug holiday
Knowledge-focused Recruiting nowThis small pilot study tests whether giving a one-time dose of vitamin K before surgery can safely lower the blood-thinning effect of warfarin, so patients can keep taking their regular medication without interruption. The study will enroll 20 adults who have been on warfarin for…
Matched conditions: ANTICOAGULANT THERAPY
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC