New device seals Stroke-Causing heart pouch during bypass surgery
NCT ID NCT07360899
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a device called AtriLASH that closes a small heart pouch (the left atrial appendage) during planned heart surgery in 200 people with atrial fibrillation. The goal is to prevent blood clots that cause strokes, potentially reducing the need for blood-thinning medications. Researchers will check if the pouch stays closed after 3 months and track any strokes or bleeding events.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AtriLASH device (suture-based closure device made of Seralene material)
- What this could lead to
- If successful, this could offer a safer way to reduce stroke risk in atrial fibrillation patients undergoing heart surgery, potentially allowing some to stop long-term blood thinners.
- What could go wrong
- This is a single-arm study with no comparison group, so benefits are uncertain. The device may not fully close the appendage, and risks like bleeding or embolism remain. Long-term stroke reduction is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institute of cardiovascular diseases Vojvodina
RECRUITINGKamenitz, Vojvodina, 21204, Serbia
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Other studies related to the condition(s) this trial covers.
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- Can a Wrist-Worn sensor outsmart atrial fibrillation?