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New hope for stroke patients: could a pill combo replace the needle?

NCT ID NCT07111559

Recruiting now Disease control Sponsor: Nippon Medical School Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This study compares two treatments for small ischemic strokes (lacunar strokes): a combination of antiplatelet drugs (pills) versus the standard clot-busting drug tPA given through an IV. The goal is to see if the pill combo works just as well but causes fewer bleeding problems. About 500 adults who have had a small stroke within the last 4.5 hours will take part, and their recovery will be checked after 3 months.

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Conditions

The condition(s) this trial relates to.

cerebral infarction ischemic stroke stroke disorder Stroke, Lacunar

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC STROKE LACUNAR STROKE STROKE

Contacts and locations

Locations

  • Dokkyo Medical University Hospital

    RECRUITING

    Tochigi, Japan

  • Fukuoka Red Cross Hospital

    RECRUITING

    Fukuoka, Japan

  • Japanese Red Cross Kyoto Daini Hospital

    RECRUITING

    Kyoto, Japan

  • Jichi Medical University Hospital

    RECRUITING

    Shimotsuke, Japan

  • Juntendo University Hospital

    RECRUITING

    Tokyo, Japan

  • Juntendo University Urayasu Hospital

    RECRUITING

    Urayasu, Japan

  • Kagoshima City Hospital

    RECRUITING

    Kagoshima, Japan

  • Kagoshima Medical Center

    RECRUITING

    Kagoshima, Japan

  • Kansai Medical University Hospital

    RECRUITING

    Hirakata, Japan

  • Kawasaki Medical School General Medical Center

    RECRUITING

    Okayama, Japan

  • Kawasaki Medical School Hospital

    RECRUITING

    Kurashiki, Japan

  • Kohnan Hospital

    RECRUITING

    Sendai, Japan

  • National Cerebral and Cardiovascular Center

    RECRUITING

    Osaka, Japan

  • Nippon Medical School Tamanagayama hospital

    RECRUITING

    Tama, Japan

  • Nippon Medical School hospital

    RECRUITING

    Tokyo, Japan

  • Ota Memorial Hospital

    RECRUITING

    Fukuyama, Japan

  • Science Tokyo Hospital

    RECRUITING

    Tokyo, Japan

  • Shioda Hospital

    RECRUITING

    Katsuura, Japan

  • St. Marianna University School of Medicine Hospital

    RECRUITING

    Kawasaki, Japan

  • The Jikei University Hospital

    RECRUITING

    Minatoku, Japan

  • The Jikei University West Medical Center

    RECRUITING

    Komae, Japan

  • Tokushima University Hospital

    RECRUITING

    Tokushima, Japan

  • Tokyo Rosai Hospital

    RECRUITING

    Tokyo, Japan

  • Tokyo Saiseikai Central Hospital

    RECRUITING

    Tokyo, Japan

  • Tokyo Women's Medical University Hospital

    RECRUITING

    Tokyo, Japan

  • University Hospital Kyoto Prefectural University of Medicine

    RECRUITING

    Kyoto, Japan

  • University of Fukui Hospital

    RECRUITING

    Fukui, Japan

  • University of Yamanashi Hospital

    RECRUITING

    Chūō, Japan

  • Yamaguchi University Hospital

    RECRUITING

    Ube, Japan

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