New hope for stroke patients: could a pill combo replace the needle?

NCT ID NCT07111559

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two treatments for small ischemic strokes (lacunar strokes): a combination of antiplatelet drugs (pills) versus the standard clot-busting drug tPA given through an IV. The goal is to see if the pill combo works just as well but causes fewer bleeding problems. About 500 adults who have had a small stroke within the last 4.5 hours will take part, and their recovery will be checked after 3 months.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ISCHEMIC STROKE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cerebral infarction ischemic stroke stroke disorder Stroke, Lacunar

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dokkyo Medical University Hospital

    RECRUITING

    Tochigi, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fukuoka Red Cross Hospital

    RECRUITING

    Fukuoka, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Japanese Red Cross Kyoto Daini Hospital

    RECRUITING

    Kyoto, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jichi Medical University Hospital

    RECRUITING

    Shimotsuke, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Juntendo University Hospital

    RECRUITING

    Tokyo, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Juntendo University Urayasu Hospital

    RECRUITING

    Urayasu, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kagoshima City Hospital

    RECRUITING

    Kagoshima, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kagoshima Medical Center

    RECRUITING

    Kagoshima, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kansai Medical University Hospital

    RECRUITING

    Hirakata, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kawasaki Medical School General Medical Center

    RECRUITING

    Okayama, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kawasaki Medical School Hospital

    RECRUITING

    Kurashiki, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kohnan Hospital

    RECRUITING

    Sendai, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nippon Medical School Tamanagayama hospital

    RECRUITING

    Tama, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nippon Medical School hospital

    RECRUITING

    Tokyo, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ota Memorial Hospital

    RECRUITING

    Fukuyama, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Science Tokyo Hospital

    RECRUITING

    Tokyo, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shioda Hospital

    RECRUITING

    Katsuura, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Marianna University School of Medicine Hospital

    RECRUITING

    Kawasaki, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Jikei University Hospital

    RECRUITING

    Minatoku, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Jikei University West Medical Center

    RECRUITING

    Komae, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tokushima University Hospital

    RECRUITING

    Tokushima, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tokyo Rosai Hospital

    RECRUITING

    Tokyo, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tokyo Saiseikai Central Hospital

    RECRUITING

    Tokyo, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tokyo Women's Medical University Hospital

    RECRUITING

    Tokyo, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Kyoto Prefectural University of Medicine

    RECRUITING

    Kyoto, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Fukui Hospital

    RECRUITING

    Fukui, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Yamanashi Hospital

    RECRUITING

    Chūō, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yamaguchi University Hospital

    RECRUITING

    Ube, Japan

    Contact Phone: •••-•••-•••• Email: •••••@•••••