Could a simple injection ease Post-Stroke shoulder pain?
NCT ID NCT06718413
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting hyaluronidase into the shoulder muscles can relieve pain and stiffness in stroke survivors. About 68 participants will receive either the drug or a placebo injection. Researchers will use MRI and ultrasound to measure changes in muscle health and pain over several weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyaluronidase plus saline
- What this could lead to
- If it works, this could offer a new treatment option for chronic shoulder pain after stroke, improving mobility and quality of life.
- What could go wrong
- This is a small, early-phase trial with only 68 participants. The treatment may not reduce pain significantly, and injections carry risks like soreness or infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
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Other studies related to the condition(s) this trial covers.
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