Could a simple injection ease Post-Stroke shoulder pain?

NCT ID NCT06718413

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether injecting hyaluronidase into the shoulder muscles can relieve pain and stiffness in stroke survivors. About 68 participants will receive either the drug or a placebo injection. Researchers will use MRI and ultrasound to measure changes in muscle health and pain over several weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hyaluronidase plus saline
What this could lead to
If it works, this could offer a new treatment option for chronic shoulder pain after stroke, improving mobility and quality of life.
What could go wrong
This is a small, early-phase trial with only 68 participants. The treatment may not reduce pain significantly, and injections carry risks like soreness or infection.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

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