Could a simple injection ease Post-Stroke shoulder pain?
NCT ID NCT06718413
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether injecting hyaluronidase into the shoulder muscles can relieve pain and stiffness in stroke survivors. About 68 participants will receive either the drug or a placebo injection. Researchers will use MRI and ultrasound to measure changes in muscle health and pain over several weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyaluronidase plus saline
What this could lead to
If it works, this could offer a new treatment option for chronic shoulder pain after stroke, improving mobility and quality of life.
What could go wrong
This is a small, early-phase trial with only 68 participants. The treatment may not reduce pain significantly, and injections carry risks like soreness or infection.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-••••