New study tests simpler blood thinner regimen after heart procedure

NCT ID NCT04796714

Recruiting now Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two blood thinner strategies after left atrial appendage closure (LAAC) in people with atrial fibrillation. Sixty participants will receive either aspirin alone or aspirin plus clopidogrel for three months. The goal is to see which approach better prevents small brain lesions seen on MRI scans, which are linked to stroke risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aspirin and clopidogrel (antiplatelet drugs)
What this could lead to: If successful, this could show that aspirin alone is as effective as dual therapy after LAAC, potentially simplifying treatment and reducing bleeding risks.
What could go wrong: This is a small, early-phase trial (60 participants) focused on MRI findings, not clinical outcomes. Results may not apply to all patients, and the best strategy remains uncertain.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTICOAGULANTS ATRIAL APPENDAGE ATRIAL FIBRILLATION PLATELET AGGREGATION INHIBITORS STROKE

New study tests simpler blood thinner regimen after heart procedure

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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