New imaging technique could reveal hidden clot sources in stroke

NCT ID NCT05636748

Recruiting now Knowledge-focused Sponsor: University of Edinburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new PET scan tracer called 18F-GP1 that sticks to activated platelets in blood clots. Researchers will scan 120 adults who recently had an ischemic stroke to see if they can find where clots are coming from. The goal is to better understand different types of stroke and improve how doctors diagnose the cause.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 18F-GP1 (a radioactive tracer that binds to activated platelets in blood clots)
What this could lead to: If successful, this imaging technique could help doctors identify the source of blood clots in stroke patients, leading to more targeted treatments.
What could go wrong: This is an early imaging study with only 120 participants, so it may not change clinical practice. The tracer may not detect all types of clots, and results may not apply to all stroke patients.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PET STROKE THROMBOSIS

Contacts and locations

Locations

Clinical Research Facility
RECRUITING

Edinburgh, United Kingdom

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