THROMBOSIS

This study looks at whether giving platelet transfusions only when platelet levels are very low is better for extremely premature babies (born at 23-26 weeks) than giving them at a higher threshold. The goal is to see if this approach helps more babies survive without major bleed…

This early-phase study tests a new radioactive tracer called 64Cu-FBP8 that lights up blood clots on PET-MR scans. Researchers want to see if it can safely and accurately detect clots in people with atrial fibrillation, cancer, COVID-19, or other clot risks. About 165 participant…

This study tests a new imaging test (PET-CT scan) that can see blood clots in the heart arteries from outside the body. The goal is to better identify what caused a heart attack, so patients get the right treatment. Researchers will recruit 80 adults who recently had a heart atta…

This study looks at the best way to prevent blood clots in people with leg casts or splints after an injury. For those at high risk of clots, it compares pills to standard injections. For those at low risk, it checks if any medication is better than just advice. Over 10,000 parti…

This study is creating a registry to collect information on antiphospholipid syndrome (APS) patients who are taking direct oral anticoagulants (DOACs). Researchers will track about 500 adults to see how often blood clots or bleeding occur. The goal is to better understand the saf…

This study looks at whether generative AI can help doctors better diagnose complications of rheumatoid arthritis (RA), such as lung disease or heart problems. Researchers will use AI to analyze patient records and suggest possible complications, then see if doctors find these sug…

This study looks at why newborns with severe heart disease are more likely to develop dangerous blood clots after heart surgery. Researchers will collect blood samples from 10 babies to study tiny molecules called microRNAs that may control clotting. The goal is to better underst…

This study is testing whether a special blood test (thrombin generation assay) can help predict which cancer patients with blood clots are at higher risk of bleeding while taking blood thinners. Researchers will follow 212 patients for 6 months to see if the test results match bl…

This study collects blood, urine, and stool samples from 500 adults with or at risk for heart and blood vessel diseases. The samples are stored in a biobank for future research on inflammation, metabolism, and other disease pathways. No treatments or interventions are given; the …

This study looks at how platelets—cells that help blood clot—work in healthy adults. Researchers will follow 400 volunteers for up to 10 years, taking blood samples and asking about diet, exercise, and health habits. The goal is to understand normal platelet function and how it c…

This study aims to better understand the role of blood clots in different types of stroke. Researchers will use a special PET scan tracer that sticks to activated platelets, the cells that form clots, to see where clots are in the body. The study will involve 120 adults who have …

This study looks at over 12,000 people with coronary heart disease who take blood thinners. These drugs can cause serious clots or bleeding. Researchers will use advanced tests on blood samples and combine them with medical images and computer models to find better ways to predic…

This study is creating a huge database of health information from up to 200,000 people with blood disorders like hemophilia, sickle cell disease, and thrombosis. Researchers will use this data to better understand these conditions and improve treatments. Anyone seen at a particip…

This study follows 3,000 people with non-cancer blood disorders (like hemophilia, sickle cell disease, and clotting issues) to see how well treatments work and what side effects occur over time. Researchers will collect safety data, including allergic reactions, infections, and o…

This study observes 1,300 critically ill ICU patients to see if the level of a blood thinner (enoxaparin) in their blood is linked to dangerous blood clots. Researchers will track clots, bleeding, and patient outcomes like survival and hospital stay length. The goal is to find be…