New global registry tracks safety of common blood thinners in APS patients

NCT ID NCT04262492

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is creating a global registry of 500 adults with antiphospholipid syndrome (APS) who are taking direct oral anticoagulants (DOACs) like rivaroxaban or apixaban. Researchers will track rates of recurrent blood clots and bleeding over at least 6 months. The goal is to gather real-world safety information for this specific patient group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Direct oral anticoagulants (rivaroxaban, dabigatran, apixaban, edoxaban)

What this could lead to

If successful, this registry could provide clearer safety data on using DOACs in low-risk APS patients, potentially guiding future treatment decisions.

What could go wrong

This is an observational registry, not a controlled trial, so it cannot prove cause and effect. Results may be limited by patient selection and real-world variability.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

antiphospholipid syndrome thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stéphane Zuily

    RECRUITING

    Nancy, 54500, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact