Your DNA could determine which heart drug works best

This trial investigates whether a common genetic variation in the CES1 gene affects how the body processes two antiplatelet drugs, clopidogrel and ticagrelor. Healthy volunteers of Amish descent will take each drug for eight days in a crossover design, and researchers will measure platelet function before and after treatment. The goal is to see if genetic differences can predict which drug works better for a given person, potentially paving the way for personalized antiplatelet therapy.