Can a frailty score guide heart attack treatment for the elderly?
NCT ID NCT04488536
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
This study looks at how frailty, a measure of biological age, influences the care and outcomes of patients hospitalized with a heart attack. Researchers will analyze data from the Swedish SWEDEHEART registry, which includes information on thousands of patients. They will compare treatment patterns and outcomes, such as death and complications, across different levels of frailty. The goal is to see if frailty can help doctors decide which patients might benefit from more invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Frailty assessment using the Clinical Frailty Scale
- What this could lead to
- If frailty proves to be a strong predictor of outcomes, doctors could use it to tailor heart attack treatments for older adults, potentially improving survival and reducing complications.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The results may be influenced by factors not fully accounted for, and the findings may not apply to all heart attack patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2020
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
SWEDEHEART is a national quality registry, which collects information on all patients hospitalized with MI or suspected MI. All 72 Swedish hospitals with acute coronary care contribute with data. From January 1st 2020 Clinical Frailty Scale, the 9-degree-version (CFS-9) is a mandatory variable in the registry. However, as a pilot project to ensure feasibility, five hospitals began to register frailty November 1st, 2017. Inclusion criteria: patients consecutively included in the SWEDEHEART registry from November 1, 2017. Exklusion criteria: none.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients consecutively included in the SWEDEHEART registry from November 1, 2017. Exclusion Criteria: * None.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Linkoeping University Hospital
Linköping, Ostergoetland, Sweden
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The Center for Medical Technology Assessment/IMH, Linkoeping University
Linköping, Östergötland County, 58183, Sweden
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