MYOCARDIAL INFARCTION

This study aims to find out if using a detailed imaging technique called OCT is better than standard angiography for guiding stent placement in people who have just had a major heart attack. Researchers will enroll 1,500 participants to see which method leads to fewer future hear…

This study is testing whether a non-invasive device that uses pulsed electromagnetic fields can improve blood flow to the heart in people with coronary artery disease. Researchers will enroll 120 adults who have evidence of reduced heart blood flow but are not candidates for stan…

This study aims to find out if a telehealth (remote) cardiac rehabilitation program works as well as the traditional in-person version. It will enroll over 500 adults with various heart conditions who are eligible for rehab. Researchers will compare how much participants improve …

This study is testing whether a special nursing education program helps people who recently had a heart attack feel more confident and take better care of their heart. Researchers will compare patients who get this extra support to those who receive standard care alone. The goal …

This study is testing if taking just one blood-thinning drug (ticagrelor) is better than the standard two-drug combo (ticagrelor plus aspirin) for people who have had a heart attack and are being treated with medication alone. It aims to see if the single drug reduces the risk of…

This study is testing whether modern heart failure medications alone are as effective as adding an implanted defibrillator (ICD) for preventing sudden death in heart attack survivors with weakened hearts. It will enroll over 3,500 people who have had a heart attack and now have h…

This study aims to find out if people who have recovered from a heart attack can safely stop taking their beta-blocker medication after at least one year. It will compare patients who stop the pills to those who continue taking them, checking for major heart problems. The goal is…

This study is testing if using a lower blood pressure target for patients in severe shock after a heart attack is better than the current standard. Researchers want to see if using less of a strong blood pressure medication (noradrenaline) helps patients survive and protects thei…

This large Phase 3 trial is testing whether adding two common medications to standard care can prevent future strokes, heart attacks, and other major vascular problems in high-risk patients who have recently had a stroke. It will compare a low-dose anti-inflammatory drug (colchic…

This study is testing whether an experimental drug called ziltivekimab can reduce the fatty plaque buildup in heart arteries of people who recently had a heart attack. About 332 participants will be randomly assigned to receive either the drug or a placebo (dummy treatment) for 1…

This study is testing if starting a cholesterol-lowering injection called inclisiran soon after a heart attack helps prevent future heart-related events like another heart attack or stroke. It will follow 300 patients in Russia for one year to see if the drug, added to their usua…

This study is testing whether a diabetes medication called dapagliflozin can help limit the amount of heart muscle damage in people who have just had a major heart attack (STEMI). The trial will enroll 256 patients who are undergoing emergency heart artery opening. Participants w…

This study is testing a noninvasive, targeted radiation treatment for people with a dangerous, fast heart rhythm called ventricular tachycardia (VT) that hasn't responded to standard drugs or procedures. The treatment, called stereotactic body radiotherapy (SBRT), aims to precise…

This study aims to find a safer long-term treatment for people who have had a heart attack and are at high risk of bleeding. Researchers are testing if using a quick genetic test to guide the choice of a milder blood-thinning drug can reduce serious bleeding events just as effect…

This study tests whether cooling the heart's arteries with cold saline during a standard heart attack procedure can prevent additional damage that sometimes occurs when blood flow is restored. Researchers will compare this cold therapy approach against standard treatment in 60 pe…

This study is testing whether a handheld stress-relief device, used alongside standard cardiac rehab, can improve blood vessel health and lower future heart disease risk in people who recently had a heart attack. Researchers will compare 100 participants using the device daily fo…

This study is testing if a newer type of stomach acid medicine (tegoprazan) is as good as a standard medicine (rabeprazole) at preventing serious stomach problems like ulcers and bleeding. It involves over 3,000 adults with heart disease who are taking long-term blood thinners, w…

This study aims to find better ways to identify people at very high risk of heart attacks or strokes before they have any symptoms. Researchers will compare two approaches: using standard risk calculators versus adding special heart and neck artery scans. The goal is to see if sc…

This study is testing a new type of heart scan to see if it can detect blood clots inside the heart's arteries. The goal is to better understand what caused a patient's heart attack, as not all heart attacks are caused by clots. Researchers will enroll 80 people who recently had …

This study is testing a new, non-invasive scanning method called magnetocardiography (MCG) to see if it can accurately detect and locate heart attacks. Researchers will enroll about 3,800 people, including healthy volunteers and patients with chest pain, to build a computer model…

This study is testing a new type of heart scan to see if it can accurately detect remaining blockages in heart arteries after someone has had a heart attack. Researchers want to know if this non-invasive scan can work as well as the current standard test, which requires inserting…

This study aims to find the hidden causes of heart attacks in people whose main heart arteries are not blocked. Researchers will use two advanced scanning techniques during a standard heart procedure and follow participants for up to 10 years to see if they have more heart proble…

This study is testing whether a home exercise plan delivered through a smartphone app can help people who have had a heart attack. It focuses on reducing their fear of physical activity (kinesiophobia) and improving their ability to walk and function. The goal is to see if this d…

This study is creating a large registry to track the health of 60,000 patients who have both chronic kidney disease and heart problems. The goal is to better understand how these conditions interact and affect patient outcomes like hospital readmissions and survival. By analyzing…

This study aims to understand how many people develop anxiety or post-traumatic stress disorder (PTSD) after a heart attack. Researchers will follow 100 patients for six months, using questionnaires, blood tests, and heart exams to measure stress levels and mental health. The goa…

This study aims to understand how often heart problems and other complications happen after same-day outpatient surgery. It will follow 15,000 adults for 90 days after their procedure to identify risk factors and create better tools to predict which patients are safest for this t…

This study is creating a long-term registry to learn more about a puzzling type of heart attack where the main heart arteries are not blocked (called MINOCA). It will follow 3,000 patients to understand what causes these events, how they are diagnosed, and what the long-term outc…

This study aims to understand why heart disease develops differently in women and men, focusing on the roles of hormones and inflammation. Researchers will collect blood samples and survey 6000 patients with chest pain to analyze hormone levels and inflammatory markers. The goal …

This study uses a special type of MRI scan to look at the tiny structure of heart muscle in people at risk for heart failure. Researchers want to understand how the heart's internal architecture changes before symptoms develop. The study includes both healthy adults and people wh…

This study aims to understand how often people with psoriasis have hidden heart problems and what puts them at risk. Researchers will follow 1,000 adults with psoriasis, checking their blood for specific markers and performing detailed heart scans. The goal is to find early signs…

This study aims to understand why women tend to have worse recovery and higher risk of heart failure after a heart attack compared to men. Researchers will follow 1,650 people for up to 10 years, using heart imaging scans to track how the heart's size and shape change over time. …

This study aims to find out if the timing of a cholesterol test during a hospital stay for a heart attack affects the treatment plan a patient receives. Researchers will observe about 100 patients, testing their cholesterol levels on the day they are admitted and again two days l…

This study aims to understand why some people have worse outcomes after a major heart attack. Researchers will follow 300 patients for five years, collecting blood samples and heart scans to identify new markers that predict future heart problems. The goal is to build a detailed …

This study aims to learn more about platelets—tiny blood cells involved in clotting—in people who have had a heart attack. Researchers will collect blood samples from 350 participants during their initial hospital procedure and again two months later. The goal is to compare plate…

This study is testing a new imaging technique to better understand dangerous, fast heartbeats (ventricular tachycardia) that can cause sudden death. Researchers want to see if combining special heart scans with detailed electrical maps can help doctors more accurately target trea…

This study is collecting real-world information on 20,000 heart attack patients in London who were sent home early after a common artery-opening procedure. The goal is to understand how these patients fare after leaving the hospital, what medications they take, and their quality …