Could a simple breathing device help heal hearts after a heart attack?

NCT ID NCT04521699

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study at Mayo Clinic tests whether using a CalmiGo device—a small inhaler-like tool that guides slow breathing and grounding—can improve blood vessel function and reduce heart disease risk in people recovering from a heart attack. One hundred adults in cardiac rehab will either use the device plus standard care or standard care alone for 12 weeks. Researchers will measure changes in blood vessel health, stress markers, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CalmiGo stress management device (a handheld device using guided breathing and grounding techniques)

What this could lead to

If it works, this could point toward a simple, drug-free way to reduce stress and improve heart health after a heart attack.

What could go wrong

This is a small, early-stage study with only 100 participants. The device may not show a clear benefit over standard care, and results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact