Chilling the heart: could cooling arteries prevent attack aftermath?
NCT ID NCT06567249
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new way to reduce heart damage after a severe heart attack (STEMI). Doctors will cool the heart's arteries during the standard procedure to open blocked vessels. The goal is to see if this cooling prevents further injury and improves heart function. The trial involves 60 adults with a recent heart attack.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Acute ST-elevation myocardial infarction * Time from onset of symptoms less than 12 hours * Given informed consent Exclusion Criteria: * Contraindication to MRI * Cardiogenic shock * Conduction disturbance: Atrioventricular block: 2nd and 3rd degree. SA block. * Sick sinus syndrome requiring implantable pacemaker * Pulmonary edema * Active inflammatory condition * Active chemo/radiation therapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cardiology Research Institute, Tomsk National Research Medical Center
RECRUITINGTomsk, 634012, Russia
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Other studies related to the condition(s) this trial covers.
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- Can a common supplement shield the heart from reperfusion injury?