A simple ultrasound test may sharpen heart attack risk predictions

NCT ID NCT07797634

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
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Paused for now. It may or may not start again.
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Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This study looks at whether a specific heart ultrasound measurement, called left atrial reservoir strain, can better predict serious heart problems within 6 months after a non-ST-elevation heart attack (NSTEMI). Researchers will measure this strain in 150 patients and compare its predictive power against standard tools like the GRACE 2.0 score and other echocardiographic parameters. The goal is to see if this measurement adds valuable information for identifying patients at higher risk of events like cardiac death, recurrent heart attack, or heart failure hospitalization.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could give doctors a better way to predict which NSTEMI patients face higher risk of heart events within 6 months, leading to more tailored follow-up care.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The measure may not add much beyond existing tools, and results may not apply to all heart attack patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients admitted with NSTEMI to the Cardiology Department / Coronary Care Unit of Assiut University Hospital who meet the eligibility criteria.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \> 18 years * Confirmed diagnosis of NSTEMI according to current ESC/ACC guidelines * Willingness to provide informed consent and complete 6-month follow-up * Undergoing coronary angiography or revascularization during the index hospitalization Exclusion Criteria: * ST-elevation myocardial infarction (STEMI) * Atrial fibrillation or other significant arrhythmia at presentation * Moderate to severe valvular heart disease (especially mitral valve disease) * Prior cardiac surgery or valve replacement * Poor echocardiographic image quality precluding reliable strain analysis * Chronic kidney disease on dialysis * Known cardiomyopathy (hypertrophic, dilated, or infiltrative) * Pregnancy * Refusal to participate

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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