ACUTE CORONARY SYNDROME

This study aims to see if treating a common stomach infection can prevent dangerous gastrointestinal bleeding in heart attack patients who have received stents and must take blood-thinning medications. It will compare a new two-drug infection treatment against a standard stomach …

This study is testing if combining three standard heart medications into a single 'polypill' can help people recover better after a heart attack. The goal is to see if taking one pill instead of three improves how well patients stick to their medication, which could lower the ris…

This international study is testing whether using just one blood-thinning medication is as safe and effective as using two after a specific type of heart artery procedure. It focuses on patients aged 75 and older or those at high risk for bleeding. The goal is to find the best ba…

This study is testing if a simpler medication plan is safe and effective for people who have had a heart attack and received a stent. After the procedure, participants will take just one strong blood thinner (ticagrelor) plus a low-dose anti-inflammatory drug (colchicine), instea…

This study tests whether the drug dalcetrapib can prevent future heart attacks and strokes in people who recently had a heart-related hospitalization. It enrolls 2,000 participants with a specific genetic profile (AA genotype) who are clinically stable after their recent cardiac …

This study is testing if a new risk score can help doctors decide the best time to reduce the intensity of blood-thinning therapy for patients who had a heart attack and received a stent. About 3,500 participants will be assigned to have their medication adjusted either after 1 m…

This study is testing if starting a cholesterol-lowering medication called inclisiran very early after a heart attack or severe chest pain (acute coronary syndrome) is safe and effective. About 300 hospitalized patients will receive either inclisiran or a placebo (dummy injection…

This study is testing a new type of heart stent called Freesolve, which is made of magnesium and dissolves over time. It is being compared to a standard, permanent metal drug-coated stent (Xience) in 1,859 patients with blocked heart arteries. The main goal is to see if the disso…

This study aims to find out if a less invasive procedure using stents (PCI) is as safe and effective as traditional open-heart bypass surgery (CABG) for people having a serious type of heart attack warning. It will enroll 1000 adults with multiple clogged heart arteries. Particip…

This study aims to find out whether taking two blood-thinning medications (ticagrelor plus aspirin) works better than taking aspirin alone to keep bypass grafts open after heart surgery. It will follow 360 patients who recently had bypass surgery for a heart attack or unstable an…

This study is testing if adding a common antibiotic called doxycycline to standard tuberculosis (TB) treatment can protect patients' lungs and heart from long-term damage. It will involve 150 adults with active TB who have just started treatment. The goal is to see if this extra …

This study is testing if a newer type of stomach acid medicine (tegoprazan) is as good as a standard medicine (rabeprazole) at preventing serious stomach problems like ulcers and bleeding. It involves over 3,000 adults with heart disease who are taking long-term blood thinners, w…

This study is testing how well an already FDA-approved implanted device works in real-world use. The device, called the Guardian, is placed under the skin and is designed to detect early signs of a heart attack and alert the patient. Researchers are enrolling 500 people who are a…

This study compares two devices doctors use during heart stent procedures to measure blood flow blockages. Researchers want to see if a newer, easier-to-use pressure catheter works as well as the standard pressure wire at preventing future heart problems. About 2,500 patients wit…

This study is testing a new bedside device called CardiAQ MCG that uses magnetic fields to detect heart attacks and blocked arteries. Researchers will enroll 150 patients who are already scheduled for heart procedures to see if the device's readings match what doctors find during…

This study is testing a new, non-invasive scanning method called magnetocardiography (MCG) to see if it can accurately detect and locate heart attacks. Researchers will enroll about 3,800 people, including healthy volunteers and patients with chest pain, to build a computer model…

This study is testing whether an online therapy program can help people who have had a heart attack manage their anxiety about their heart health. Researchers will compare an online cognitive behavioral therapy (CBT) program designed for this specific anxiety to a general online …

This study aims to understand why heart disease develops differently in women and men, focusing on the roles of hormones and inflammation. Researchers will collect blood samples and survey 6000 patients with chest pain to analyze hormone levels and inflammatory markers. The goal …

This study aims to improve how doctors identify the specific type of plaque that causes a heart attack. Researchers will compare high-resolution artery images taken during a standard procedure with a detailed analysis of tiny tissue samples removed from the blockage. The goal is …

This study aims to better understand heart attacks and heart injuries by collecting detailed information from 11,000 patients. Researchers will observe which treatments patients receive and track their long-term health outcomes. The goal is to gather knowledge to potentially impr…