New stomach drug could match standard care for heart patients at bleeding risk

NCT ID NCT04416581

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study compares a new stomach acid reducer (tegoprazan) with a standard one (rabeprazole) in about 3,320 heart patients who take blood thinners and are at high risk for stomach bleeding or ulcers. The goal is to see if the new drug works just as well at preventing serious stomach problems over 12 months. Participants will be randomly assigned to one of the two drugs, and neither they nor their doctors will know which they are taking.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ajou University Hospital

    RECRUITING

    Suwon, South Korea

    Contact

    Contact

  • Asan Medical Center

    RECRUITING

    Seoul, South Korea

    Contact Email: •••••@•••••

    Contact

  • Bucheon Sejong Hospital

    RECRUITING

    Bucheon-si, South Korea

    Contact

    Contact

  • Bundang CHA Hospital

    RECRUITING

    Seongnam, South Korea

    Contact

    Contact

  • Chonnam National University Hospital

    RECRUITING

    Gwangju, South Korea

    Contact

    Contact

  • Chung-Ang University Hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Chungbuk National University Hospital

    RECRUITING

    Cheonju, South Korea

    Contact

    Contact

  • Chungnam National University Hospital

    RECRUITING

    Daejeon, South Korea

    Contact

    Contact

  • Chungnam National University Sejong Hospital

    RECRUITING

    Sejong, South Korea

    Contact

    Contact

  • Dankook University Hospital

    WITHDRAWN

    Cheonan, South Korea

  • Dong-A Medical Center

    RECRUITING

    Pusan, South Korea

    Contact

    Contact

  • Ewha Womans University Medical Center

    WITHDRAWN

    Seoul, South Korea

  • Gangneung Asan Hospital

    RECRUITING

    Gangneung, South Korea

    Contact

    Contact

  • Gangwon National Univ. Hospital

    WITHDRAWN

    Chuncheon, South Korea

  • Gyeongsang National University Changwon Hospital

    WITHDRAWN

    Changwon, South Korea

  • Hallym University Chuncheon Sacred Heart Hospital

    NOT_YET_RECRUITING

    Chuncheon, South Korea

    Contact

    Contact

  • Hallym University Dongtan Sacred Heart Hospital

    RECRUITING

    Hwaseong-si, South Korea

    Contact

    Contact

  • Hallym University Sacred Heart Hospital

    RECRUITING

    Anyang, South Korea

    Contact

    Contact

  • Hanyang University Guri Hospital

    RECRUITING

    Guri-si, South Korea

    Contact

    Contact

  • Hanyang University Seoul Hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Inje University Ilsan Paik Hospital

    RECRUITING

    Ilsan, South Korea

    Contact

    Contact

  • Inje University Pusan Paik Hospital

    RECRUITING

    Pusan, South Korea

    Contact

    Contact

  • Jeonbuk National University Hospital

    WITHDRAWN

    Jeonju, South Korea

  • Kangbuk Samsung Hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Keimyung University Dongsan Medical Center

    RECRUITING

    Daegu, South Korea

    Contact

    Contact

  • Korea University Anam Hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Kosin University Gospel Hospital

    RECRUITING

    Busan, South Korea

    Contact

    Contact

  • Kwangju Christian Hospital

    WITHDRAWN

    Kwangju, South Korea

  • Kyung Hee University Hospital at Gangdong

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Kyung Hee University Medical Center

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Pusan National University Hospital

    NOT_YET_RECRUITING

    Pusan, South Korea

    Contact

    Contact

  • Pusan National University Yangsan Hospital

    WITHDRAWN

    Yangsan, South Korea

  • SNU Boramae Medical Center

    NOT_YET_RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Seoul National University Hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Seoul university Bundang hospital

    RECRUITING

    Seongnam-si, South Korea

    Contact

    Contact

  • Severance Hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • Sungkyunkwan University Samsung Changwon Hospital

    WITHDRAWN

    Changwon, South Korea

  • The Catholic Univ. of Korea Eunpyeong St. Mary's hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • The Catholic Univ. of Korea Seoul St. Mary's hospital

    RECRUITING

    Seoul, South Korea

    Contact

    Contact

  • The Catholic University of Korea, ST. Vincent's Hospital

    RECRUITING

    Suwon, South Korea

    Contact

    Contact

  • Ulsan University Hospital

    RECRUITING

    Ulsan, South Korea

    Contact

    Contact

  • Yeungnam University Medical Center

    WITHDRAWN

    Daegu, South Korea

  • Yonsei University Yongin Severance Hospital

    RECRUITING

    Yongin-si, South Korea

    Contact

    Contact

Conditions

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