ACUTE CORONARY SYNDROME

This large study aimed to see if taking two blood-thinning medications (clopidogrel plus aspirin) is better than taking aspirin alone for patients with multi-vessel heart disease who have received a stent. It involved 8,250 patients across 100 centers and followed them for at lea…

This study tested if adding the cholesterol-lowering drug evolocumab to standard treatment could help people who recently had a heart attack. Researchers wanted to see if the drug could better control cholesterol, reduce harmful inflammation in the heart and blood vessels, and im…

This study tested whether taking a low dose of aspirin twice a day is better than once a day at preventing future heart attacks, strokes, or other serious heart problems in people with diabetes or obesity who recently had a heart attack or chest pain. Researchers enrolled over 2,…

This large international study aimed to find the safest length of time for patients to take two blood-thinning drugs after a heart attack. It compared shorter and longer treatment durations to see which better balanced the risk of future heart problems against the risk of serious…

This study tested whether a traditional Chinese medicine capsule called Xuesaitong could help patients recover after a heart attack and stent procedure. Researchers gave the capsule, made from Panax notoginseng, to 50 patients for four weeks. They closely examined patients' blood…

This study tested whether doing cardiac rehabilitation at home using a mobile app works as well as traditional clinic visits. Researchers compared three approaches: clinic-only rehab, clinic plus app support, and app-only remote rehab. They measured heart health, fitness, and hos…

This study tested the safety and effectiveness of a refined heart stent called Xience Sierra in a broad, real-world group of 1,757 patients. It focused on patients with various heart conditions, including many with diabetes or prediabetes, who are at higher risk for future heart …

This study tested if a specific care plan using a newer cholesterol-lowering drug called inclisiran works better than standard care for people recovering from a recent heart attack. About 400 participants, who still had high cholesterol despite taking standard medication, were as…

This study looked at whether a medication called vericiguat helps people who recently had a heart attack and have weakened heart pumping. Researchers followed 149 patients to see if those taking the drug regularly had fewer hospitalizations for heart failure or deaths from heart …

This study tested whether giving doctors a computer decision-support tool helps patients get better cholesterol management after a heart attack. Over 1,100 patients at hospitals that either used the tool or followed standard care were compared. Researchers wanted to see if the to…

This large, completed study tested whether adding an experimental oral medication called milvexian to standard care could better prevent future major heart problems in people who recently had a heart attack or unstable chest pain. Over 14,000 high-risk participants were randomly …

This study tested whether giving the anti-inflammatory drug colchicine to patients before and after heart bypass surgery could reduce serious complications. It involved 100 patients who had recently suffered a heart attack and needed bypass surgery. Patients received either colch…

This study tested whether sending educational and supportive text messages could help people better manage their health in the year after a serious heart event. It involved 370 patients who had recently been hospitalized for a heart attack or similar condition. The goal was to se…

This study looked at whether patients who were hospitalized for serious heart or stroke events received the recommended cholesterol-lowering medications when they left the hospital. Researchers followed 129 patients to see if doctors prescribed drugs proven to significantly lower…

This study tested if adding a cholesterol-lowering drug called evolocumab to standard care could help patients who recently had a specific type of heart attack (NSTEMI). Researchers wanted to see if the drug could further reduce 'bad' cholesterol and, importantly, lower inflammat…

This study tested a simpler, more stable method for placing drug-coated stents (tiny mesh tubes) in the heart arteries of 161 patients with acute chest pain or heart attacks. Doctors used special imaging to guide the stent placement and inflated the balloon at a steady, moderate …

This small pilot study tested whether a new hybrid cardiac rehab program using telehealth could work for people recovering from a heart attack. The program mixed 5 in-clinic sessions with 19 home-based sessions over 12 weeks, aiming to make rehab more convenient. Researchers comp…

This study checked if the Orsiro heart stent works as well in regular medical practice as it did in earlier research. It followed 556 people with clogged heart arteries who received the stent. Researchers tracked their health for 5 years to see how safe and effective the stent re…

This study tested if sending heart attack patients home with special remote monitoring equipment could help them manage their recovery and avoid unnecessary trips back to the hospital. Over 300 patients who recently had a heart attack were randomly assigned to either receive the …

This study tested whether a moderate dose of cholesterol-lowering medication (statins) works as well as a high dose for people recovering from a heart attack. Researchers wanted to see if the lower dose could achieve the same cholesterol-lowering goal while possibly causing fewer…

This study aimed to create a personalized tool to predict which heart attack patients are most likely to experience future heart problems or complications from their medications. Researchers followed over 1,600 patients for two years, collecting information about their health, te…

This study tested a new decision-making tool for family doctors to use when a patient comes in with chest pain. The tool combines a simple checklist with a quick blood test to help doctors decide if a patient is likely having a heart attack and needs to go to the hospital. The go…

This study analyzed data from over 5,000 patients to see if simple heart tests done in an ambulance can safely and accurately identify people having a specific type of heart attack (NSTE-ACS). The goal is to help paramedics decide the best hospital for each patient, potentially a…

This study analyzed existing medical data from 1,793 people who had a type of heart attack called acute coronary syndrome. The goal was to find common signs or 'predictors' that a patient's heart attack was caused by a specific problem called plaque erosion, rather than a rupture…

This study aimed to understand how different doses of aspirin, a common heart medication, affect the body's immune system. Researchers gave 72 healthy volunteers various combinations of aspirin and another drug (ticagrelor) for short periods. They then triggered a temporary, mild…

This study aimed to understand how well two different types of heart stents heal inside arteries after a severe heart attack. Researchers enrolled 22 patients who had a heart attack and needed a stent. They used a special imaging camera inside the artery to see how the stents wer…

This study observed how Italian hospital doctors actually use different blood-thinning medications to treat patients having heart attacks. Researchers tracked 2,806 patients over four weeks to see which drug combinations, doses, and timing were used during hospitalization. The go…

This early-stage study aimed to understand how a new drug called vicagrel compares to the standard drug clopidogrel in the bodies of healthy people. It involved 18 healthy volunteers with a specific normal metabolism. The main goal was to measure and compare the levels of each dr…

This study looked at 2000 patients who had a heart attack to see how many had an inherited condition causing very high cholesterol. The goal was to understand this link better, so doctors can improve screening for people at high risk. It did not test a new treatment but gathered …

This study monitored 1005 heart attack patients who received artery-opening procedures to understand the safety of switching from an intravenous blood thinner (cangrelor) to oral blood thinners (clopidogrel, prasugrel, or ticagrelor). Researchers tracked patients for 30 days afte…

This study aimed to understand how inflammation, measured by a blood protein called CRP, changes in people having a severe heart attack. Researchers tracked CRP levels in 35 patients from their first medical contact through their hospital stay after emergency artery-opening surge…

This study aims to understand why some people have heart attacks even when they don't have common risk factors like smoking, high blood pressure, high cholesterol, or diabetes. Researchers will compare 1000 patients who had heart attacks, looking at their medical history, blood t…

This study looked at 88 patients who had a heart attack and needed an imaging procedure. Researchers tracked various health details to figure out which patients were most likely to develop kidney damage from the dye used during the procedure. The goal is to help doctors better pr…