Aspirin doses tweak immune response in healthy volunteers

NCT ID NCT03869268

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tested how different doses of aspirin affect the body's immune response. Healthy volunteers took various aspirin doses for 10-14 days, then received a substance that temporarily mimics flu-like symptoms. Researchers measured immune markers in blood and urine to see if lower doses reduce immune activity. The goal is to improve heart attack treatments by balancing clot prevention with immune effects.

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Contacts and locations

Locations

  • Sheffield Teaching Hospitals NHS Foundation Trust

    Sheffield, South Yorkshire, S5 7AU, United Kingdom

Conditions

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