Hidden gene changes may raise heart risk even after quitting smoking
NCT ID NCT04987268
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study looked at 1029 patients who had a heart attack or unstable angina and quit smoking. Researchers checked for certain gene mutations (called CHIP) in their blood. They wanted to see if these mutations are linked to a higher chance of future heart problems, like another heart attack or stroke, even after stopping smoking. The goal is to better understand why some former smokers still face heart risks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify which former smokers with heart disease are at higher risk for future heart problems, leading to more personalized care.
What could go wrong
This is an observational study, not a treatment trial. It only looks for a link, so it cannot prove cause and effect. Results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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General Hospital of Shenyang Military Region
Shenyang, Liaoning, 110016, China