Ultrasound 'Memory' imaging may reveal hidden heart ischemia
NCT ID NCT07762495
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This trial tests whether a special ultrasound technique can detect heart muscle ischemia (reduced blood flow) in people with suspected acute coronary syndrome. The approach uses microbubbles that stick to activated immune cells and blood vessel linings, potentially revealing inflammation even after the ischemia has resolved. Researchers will compare the imaging results with a final diagnosis made by an expert committee to see how accurate the test is.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Myocardial contrast echocardiography (MCE) molecular imaging with Sonazoid, a contrast agent containing microbubbles designed to stick to activated immune cells and blood vessel linings to reveal inflammation from ischemia.
- What this could lead to
- If it works, this could lead to a quick, bedside ultrasound test that helps doctors rapidly confirm or rule out a heart attack, potentially speeding up treatment and reducing unnecessary hospital stays.
- What could go wrong
- This is an early, proof-of-concept study with a small number of patients, so the imaging may not be accurate enough for routine use. There is also a small risk of allergic reactions to the contrast agent.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE CORONARY SYNDROME are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a heart MRI replace invasive scans for some heart attacks?
- Can a tailored Blood-Thinner combo prevent second heart attacks without causing bleeding?
- A sharper eye on the heart: new blood test aims to spot heart attacks faster
- Marathon runners and heart patients put a new troponin test to the ultimate challenge
- Bedside flu shot for heart patients: a simple strategy to save lives?
- Could a Two-Drug combo stop repeat heart attacks?