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Marathon runners and heart patients put a new troponin test to the ultimate challenge

NCT ID NCT07726420

Recruiting now Diagnosis Sponsor: Technical University of Munich Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This study tests whether a lab technique called polyethylene glycol (PEG) precipitation can tell the difference between a true heart attack and a harmless condition called macrotroponin, where troponin molecules clump together and falsely signal heart damage. Researchers will compare results from 160 participants: people hospitalized with acute coronary syndrome and healthy marathon runners before and after a race. The goal is to establish clear cut-off values for the test, potentially preventing unnecessary heart procedures in people who are actually healthy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a diagnostic test using polyethylene glycol (PEG) precipitation to distinguish macrotroponin from true troponin elevation
What this could lead to
If successful, this could give doctors a quick, reliable way to avoid false heart-attack alarms and unnecessary procedures.
What could go wrong
This is an early diagnostic study, not a treatment trial. The test may not prove accurate enough for routine use, and cut-off values remain unestablished.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome disease ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIAGNOSES DISEASE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Technical University Munich

    RECRUITING

    Munich, Bavaria, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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