Technical University Of Munich

This study tests whether using a 3 Tesla MRI during surgery for brain metastases helps surgeons remove tumors more completely. About 154 adults will be randomly assigned to standard surgery or surgery with the MRI. The goal is to see if the MRI leads to better tumor removal and f…

This study looks at two ways to treat a specific type of neck fracture (odontoid fracture) in people aged 70 and older. Participants will be randomly assigned to either surgery or wearing a rigid neck collar. The goal is to see which treatment helps them recover better in daily a…

This study tests whether a 4-week whole-food plant-based diet can improve immune function and slow disease activity in people with early-stage chronic lymphocytic leukemia (CLL) who have not yet received treatment. Fifty participants will follow the diet and provide blood and sto…

This study tests whether giving ICU patients extra protein and activating their muscles early (using electrical stimulation and movement) can prevent severe muscle loss. About 40 critically ill adults on ventilators will take part. The goal is to see if this approach helps patien…

This study looks at whether combining a heart procedure called ablation with a 12-week home exercise program can improve how well the body uses oxygen in people with a type of heart failure (HFpEF) and a common heart rhythm problem (atrial fibrillation). About 40 participants wil…

This pilot study tests whether a portable, at-home brain stimulation device (tDCS) can help people with depression maintain the improvements they achieved during hospital treatment with esketamine, rTMS, or ECT. Thirty adults will use the device for 30 minutes a day, five days a …

This study tests whether a special hydrogel, squirted into the kidney after laser stone removal, can trap tiny leftover fragments and be pulled out whole. About 120 adults with kidney stones larger than 10 mm will be randomly assigned to standard surgery alone or surgery plus the…

This study tests whether giving the COVID-19 vaccine (Comirnaty) to children starting at 6 months old can lower their chance of developing type 1 diabetes. The trial will include 2,252 children who have a high genetic risk for the disease. Half will get the vaccine, half a placeb…

This study looks at whether adding a structured exercise program is safe and helpful for people with hypertrophic obstructive cardiomyopathy who are already taking the drug mavacamten. About 24 adults with mild symptoms will either do supervised endurance and strength training fo…

This study compares two recovery plans after hip replacement surgery: a standard approach and a 'fast track' approach designed to get patients home sooner. Researchers will measure how long patients stay in the hospital and how well they recover in terms of pain, movement, and qu…

This study tests whether blood flow restriction (BFR) training can reduce pain and improve elbow function in people with tennis elbow (lateral epicondylitis) who haven't gotten better with physical therapy. Forty adults will either receive BFR training or a sham treatment during …

This study looks at whether exercising before or after breakfast or dinner changes how the body handles blood sugar after meals. Thirty healthy, active adults will run for 45 minutes at different times and wear a continuous glucose monitor. The goal is to see which timing leads t…

This study tests whether using artificial intelligence (AI) to rewrite medical discharge letters into plain language helps cancer patients better understand their diagnosis, treatment, and next steps. About 150 adults with blood cancer or other cancers will be randomly assigned t…

This pilot study tests a smartphone app that collects movement data and patient questionnaires to create a score that predicts satisfaction after knee or hip replacement. Researchers will enroll 1,250 people, including patients before or after surgery and healthy volunteers. The …

This pilot study is looking at why some patients in the intensive care unit (ICU) develop severe muscle weakness after surgery. Researchers will take blood and small muscle samples from 20 high-risk patients to look for chemical changes that might cause or signal this weakness. T…

This study is looking at how a non-invasive brain stimulation treatment called TMS changes the brain in people with depression. 100 adults will receive 20 TMS sessions over four weeks and have MRI scans at several points. The goal is to find brain imaging markers that can predict…

This study tests whether teaching married couples about money management and healthy relationships can strengthen their bond and improve their mental health. About 4,500 couples in rural and urban India will take part. The program involves six sessions and aims to reduce stress a…

This study adds a return-to-sports test to an existing knee replacement recovery study. The test uses a stepwise approach to assess athletic readiness, starting with low-level sports and progressing only if safe. Researchers hope to provide an objective way to guide patients back…