A 10-second sprint may reveal who gains the most muscle from weight training
NCT ID NCT07721766
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This study investigates whether a person's glycolytic power — how efficiently their body uses sugar for quick energy — can predict muscle growth from resistance training. Healthy adults who have not done structured weight lifting in the past year will take a 10-second all-out cycling sprint test to measure their peak lactate accumulation. Then they will complete eight weeks of supervised leg-focused weight training. Researchers will measure changes in thigh muscle thickness to see if those with higher glycolytic power gain more muscle.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hypertrophy-focused resistance training
- What this could lead to
- If it works, this could help explain why people respond differently to exercise and pave the way for personalized training programs.
- What could go wrong
- This is an early observational study, not a treatment trial. It may find no link between glycolytic power and muscle growth, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 39 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Body Mass Index (BMI) between 20-29 kg/m2 * No structured resistance training performed in the last twelve months. * Maximum of four sessions per week of recreational or low-to-moderate aerobic endurance activity. * No history of competitive strength or physique sports. Exclusion Criteria: * Diagnosed cardiovascular, pulmonary, metabolic, neuromuscular, or orthopaedic disease that contraindicates exercise. * Positive response to any question on the PAR-Q 2025 questionnaire. * Current use of anabolic steroids, creatine, or other substances known to strongly influence muscle hypertrophy. * Regular engagement in shift work. * Women who are pregnant or breastfeeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
8 sites in 4 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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DLR Cologne, Department of Metabolism and Human Performance
RECRUITINGCologne, North Rhine-Westphalia, 51147, Germany
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Institute for Applied Training Science (IAT) Leipzig
RECRUITINGLeipzig, Saxony, 04109, Germany
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TU Chemnitz, Sports Medicine and Exercise Therapy
RECRUITINGChemnitz, Saxony, 09126, Germany
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Technical University of Munich, TUM School of Medicine and Health
RECRUITINGMünchen, Bavaria, 80809, Germany
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Universidad Politécnica de Madrid, Facultad de Ciencias de la Actividad Física y del Deporte (INEF)
RECRUITINGMadrid, Madrid, 28040, Spain
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University of Jyväskylä, Faculty of Sport and Health Sciences
RECRUITINGJyväskylä, Central Finland, 40014, Finland
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University of Limerick, Department of Physical Education and Sport Sciences (PESS)
RECRUITINGLimerick, Limerick, V94 T9PX, Ireland
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iST University of Applied Sciences
RECRUITINGDüsseldorf, North Rhine-Westphalia, 40233, Germany
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