Brain scans may predict who benefits from TMS for depression

NCT ID NCT07420322

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is looking at how a non-invasive brain stimulation treatment called TMS changes the brain in people with depression. 100 adults will receive 20 TMS sessions over four weeks and have MRI scans at several points. The goal is to find brain imaging markers that can predict who will respond to TMS and who might relapse later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transcranial magnetic stimulation (TMS)
What this could lead to
If successful, this could help doctors predict which patients with depression will benefit from TMS, making treatment more personalized and effective.
What could go wrong
This is an early-stage observational study focused on brain imaging, not a treatment trial. It may not lead to immediate clinical changes, and results may not apply to all depression patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Technical University of Munich

    RECRUITING

    München, 81675, Germany