Brain scans may predict who benefits from TMS for depression

NCT ID NCT07420322

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is looking at how a non-invasive brain stimulation treatment called TMS changes the brain in people with depression. 100 adults will receive 20 TMS sessions over four weeks and have MRI scans at several points. The goal is to find brain imaging markers that can predict who will respond to TMS and who might relapse later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial magnetic stimulation (TMS)

What this could lead to

If successful, this could help doctors predict which patients with depression will benefit from TMS, making treatment more personalized and effective.

What could go wrong

This is an early-stage observational study focused on brain imaging, not a treatment trial. It may not lead to immediate clinical changes, and results may not apply to all depression patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Hospital Technical University of Munich

    RECRUITING

    München, 81675, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••