COVID-19 shot tested to stop type 1 diabetes in kids

NCT ID NCT06452654

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether giving the COVID-19 vaccine (Comirnaty) to children starting at 6 months old can lower their chance of developing type 1 diabetes. The trial will include 2,252 children who have a high genetic risk for the disease. Half will get the vaccine, half a placebo, and researchers will track who develops diabetes-related antibodies or type 1 diabetes over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

COVID-19 vaccine (Comirnaty)

What this could lead to

If it works, this could show that COVID-19 vaccination helps prevent type 1 diabetes in children with a high genetic risk.

What could go wrong

This is a large but early-stage prevention trial. It may not prove that the vaccine reduces diabetes risk, and results may take years. The vaccine has known side effects like fever or allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

COVID-19 diabetes mellitus type 1 diabetes mellitus 1 viral infectious disease type 1 diabetes mellitus prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AUF DER BULT, Kinder- und Jugendkrankenhaus

    RECRUITING

    Hanover, Lower Saxony, 30173, Germany

    Contact

  • Birmingham Women's and Children's NHS Foundation Trust

    NOT_YET_RECRUITING

    Birmingham, United Kingdom

    Contact

  • Cambridge University Hospitals NHS Foundation Trust

    NOT_YET_RECRUITING

    Cambridge, United Kingdom

    Contact

  • Klinik und Poliklinik f. Kinder und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden

    RECRUITING

    Dresden, Saxony, 01307, Germany

    Contact

  • Klinikum rechts der Isar of Technical University Munich and Institute for Diabetes Research, Helmholtz Munich

    RECRUITING

    Munich, Bavaria, 80939, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lund University Dep. of Clinical Sciences Malmo, Skane University Hospital SUS

    RECRUITING

    Malmö, 20213, Sweden

    Contact

  • Medical University of Vienna, Dept. of Pediatric and Adolescent Medicine, Waehringer Gürtel 18-20, 1090 Vienna, Austria

    NOT_YET_RECRUITING

    Vienna, 1090, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Newcastle upon Tyne Hospitals NHS Foundation Trust

    RECRUITING

    Newcastle, United Kingdom

    Contact

  • University Hospitals Leuven, Faculty of Medicine, Catholic University of Leuven

    RECRUITING

    Leuven, 3000, Belgium

    Contact