COVID-19 shot tested to stop type 1 diabetes in kids

NCT ID NCT06452654

Recruiting now Prevention Sponsor: Technical University of Munich Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether giving the COVID-19 vaccine (Comirnaty) to children starting at 6 months old can lower their chance of developing type 1 diabetes. The trial will include 2,252 children who have a high genetic risk for the disease. Half will get the vaccine, half a placebo, and researchers will track who develops diabetes-related antibodies or type 1 diabetes over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: COVID-19 vaccine (Comirnaty)
What this could lead to: If it works, this could show that COVID-19 vaccination helps prevent type 1 diabetes in children with a high genetic risk.
What could go wrong: This is a large but early-stage prevention trial. It may not prove that the vaccine reduces diabetes risk, and results may take years. The vaccine has known side effects like fever or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

COVID-19 diabetes mellitus type 1 diabetes mellitus 1 viral infectious disease type 1 diabetes mellitus prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS, TYPE 1

Contacts and locations

Locations

AUF DER BULT, Kinder- und Jugendkrankenhaus
RECRUITING

Hanover, Lower Saxony, 30173, Germany
Birmingham Women's and Children's NHS Foundation Trust
NOT_YET_RECRUITING

Birmingham, United Kingdom
Cambridge University Hospitals NHS Foundation Trust
NOT_YET_RECRUITING

Cambridge, United Kingdom
Klinik und Poliklinik f. Kinder und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden
RECRUITING

Dresden, Saxony, 01307, Germany
Klinikum rechts der Isar of Technical University Munich and Institute for Diabetes Research, Helmholtz Munich
RECRUITING

Munich, Bavaria, 80939, Germany
Lund University Dep. of Clinical Sciences Malmo, Skane University Hospital SUS
RECRUITING

Malmö, 20213, Sweden
Medical University of Vienna, Dept. of Pediatric and Adolescent Medicine, Waehringer Gürtel 18-20, 1090 Vienna, Austria
NOT_YET_RECRUITING

Vienna, 1090, Austria
The Newcastle upon Tyne Hospitals NHS Foundation Trust
RECRUITING

Newcastle, United Kingdom
University Hospitals Leuven, Faculty of Medicine, Catholic University of Leuven
RECRUITING

Leuven, 3000, Belgium

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