Arm cuff trick may shield diabetic kidneys from dye damage

NCT ID NCT07179874

Completed Prevention Sponsor: Universidad de Murcia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a non-invasive procedure called remote ischemic preconditioning (RIPC) can prevent kidney damage caused by contrast dye in diabetic patients undergoing coronary angiography. The procedure involves using a blood pressure cuff to briefly restrict blood flow to the arm in cycles. Researchers measured kidney function and oxidative stress markers in 71 participants to see if RIPC offers protection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Remote Ischemic Preconditioning (a non-invasive procedure using a blood pressure cuff to briefly restrict arm blood flow)
What this could lead to: If it works, this could offer a simple, drug-free way to protect kidneys in diabetic patients during procedures that use contrast dye.
What could go wrong: This is a small, completed study with only 71 participants, so results may not apply to everyone. Previous research has been mixed on whether this technique works in people with diabetes.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome diabetes mellitus acute kidney injury prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONTRAST INDUCED ACUTE KIDNEY INJURY

More trials for these conditions

Other studies related to the condition(s) this trial covers.