Simple test could cut unnecessary hospital visits for chest pain
NCT ID NCT05827237
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether a clinical decision rule, combining a 5-question heart score with a rapid blood test, could safely reduce unnecessary hospital referrals for chest pain. Nearly 950 adults with new chest pain were seen by their general practitioner. The goal was to see if the rule could accurately rule out a heart attack or major heart problems within 6 weeks to 6 months, while also being cost-effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Clinical decision rule (Marburg Heart Score and high-sensitive troponin I point of care test)
- What this could lead to
- If successful, this decision rule could help general practitioners safely identify low-risk chest pain patients, reducing unnecessary hospital referrals and healthcare costs.
- What could go wrong
- The rule may not be accurate enough in all populations, and false negatives could miss a heart attack. The study was completed but results are not yet widely implemented.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Leiden University Medical Center
Leiden, South Holland, 2300 RC, Netherlands
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