Heart attack mystery: study probes why 1 in 5 victims have no known risks

NCT ID NCT05535582

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed study looked at 1,000 heart attack patients to understand why some have no standard risk factors like smoking, high blood pressure, or diabetes. Researchers compared these 'SMuRF-less' patients to those with risk factors, examining their medical history, lab tests, and heart imaging. The goal is to uncover hidden biomarkers that could predict heart attacks in seemingly low-risk people.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could lead to better risk prediction tools for heart attacks in people without standard risk factors, potentially saving lives.
What could go wrong
This is an observational study, not a treatment trial. It identifies patterns but does not test a therapy, so direct patient benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hippokration General University Hospital of Thessaloniki

    Thessaloniki, Central Macedonia, 54642, Greece

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Other studies related to the condition(s) this trial covers.