Heart attack Patients' bleeding risk tracked after blood thinner switch

NCT ID NCT04471870

First seen Mar 10, 2026 · Last updated Jun 23, 2026 · Updated 16 times

Summary

This study followed over 1,000 people who had a heart attack and were given a quick-acting intravenous blood thinner called cangrelor during a procedure to open blocked arteries. Researchers wanted to see how often bleeding occurred when patients then switched to a different oral blood thinner. The goal was to gather real-world safety information, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • A.O. Mauriziano

    Torino, Italy

  • A.O. Padova

    Padova, Italy

  • A.O. Sant'Anna e San Sebastiano

    Caserta, Italy

  • A.O.R.N. A. Cardarelli

    Naples, Italy

  • A.O.U. Careggi

    Florence, Italy

  • A.O.U. Consorziale Policlinico

    Bari, Italy

  • A.O.U. Federico II

    Naples, Italy

  • A.O.U. Policlinico-Vittorio Emanuele P.O. Ferrarotto

    Catania, Italy

  • A.O.U. Riuniti

    Ancona, Italy

  • A.O.U. Sassari

    Sassari, Italy

  • ASO Santa Croce e Carle

    Cuneo, Italy

  • Aurelia Hospital

    Roma, Italy

  • Azienda Ospedaliera San Pio

    Benevento, Italy

  • Centro Cardiologico Monzino

    Milan, Italy

  • Fondazione Poliambulanza

    Brescia, Italy

  • Fondazione Policlinico Universitario A. Gemelli

    Roma, Italy

  • Fondazione Toscana "G. Monasterio" Ospedale del Cuore G. Pasquinucci

    Massa, Italy

  • Ospedale Ca' Foncello

    Treviso, Italy

  • Ospedale Fabrizio Spaziani

    Frosinone, Italy

  • Ospedale Maggiore

    Bologna, Italy

  • Ospedale S. Andrea

    La Spezia, Italy

  • Ospedale SS Annunziata

    Cosenza, Italy

  • Ospedale San Bassiano

    Bassano del Grappa, Italy

  • Ospedale San Donato

    Arezzo, Italy

  • Ospedale Santa Chiara

    Trento, Italy

  • Ospedale Santa Maria Goretti

    Latina, Italy

  • Ospedale Umberto I

    Syracuse, Italy

  • Ospedale degli Infermi

    Rivoli, Italy

  • Policlinico San Matteo

    Pavia, Italy

  • San Camillo Forlanini

    Roma, 00152, Italy

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cangrelor (intravenous blood thinner)

What this could lead to

If results are positive, it could confirm that switching from cangrelor to other blood thinners is safe in real-world practice.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove cause and effect. Bleeding risks may still vary by patient.

Conditions

The condition(s) this trial relates to.

acute coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.