Heart attack Patients' bleeding risk tracked after blood thinner switch

NCT ID NCT04471870

Completed Knowledge-focused Sponsor: Chiesi Farmaceutici S.p.A. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed over 1,000 people who had a heart attack and were given a quick-acting intravenous blood thinner called cangrelor during a procedure to open blocked arteries. Researchers wanted to see how often bleeding occurred when patients then switched to a different oral blood thinner. The goal was to gather real-world safety information, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cangrelor (intravenous blood thinner)
What this could lead to: If results are positive, it could confirm that switching from cangrelor to other blood thinners is safe in real-world practice.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove cause and effect. Bleeding risks may still vary by patient.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CORONARY SYNDROME

Contacts and locations

Locations

A.O. Mauriziano

Torino, Italy
A.O. Padova

Padova, Italy
A.O. Sant'Anna e San Sebastiano

Caserta, Italy
A.O.R.N. A. Cardarelli

Naples, Italy
A.O.U. Careggi

Florence, Italy
A.O.U. Consorziale Policlinico

Bari, Italy
A.O.U. Federico II

Naples, Italy
A.O.U. Policlinico-Vittorio Emanuele P.O. Ferrarotto

Catania, Italy
A.O.U. Riuniti

Ancona, Italy
A.O.U. Sassari

Sassari, Italy
ASO Santa Croce e Carle

Cuneo, Italy
Aurelia Hospital

Roma, Italy
Azienda Ospedaliera San Pio

Benevento, Italy
Centro Cardiologico Monzino

Milan, Italy
Fondazione Poliambulanza

Brescia, Italy
Fondazione Policlinico Universitario A. Gemelli

Roma, Italy
Fondazione Toscana "G. Monasterio" Ospedale del Cuore G. Pasquinucci

Massa, Italy
Ospedale Ca' Foncello

Treviso, Italy
Ospedale Fabrizio Spaziani

Frosinone, Italy
Ospedale Maggiore

Bologna, Italy
Ospedale S. Andrea

La Spezia, Italy
Ospedale SS Annunziata

Cosenza, Italy
Ospedale San Bassiano

Bassano del Grappa, Italy
Ospedale San Donato

Arezzo, Italy
Ospedale Santa Chiara

Trento, Italy
Ospedale Santa Maria Goretti

Latina, Italy
Ospedale Umberto I

Syracuse, Italy
Ospedale degli Infermi

Rivoli, Italy
Policlinico San Matteo

Pavia, Italy
San Camillo Forlanini

Roma, 00152, Italy

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