New stent study aims to improve heart outcomes for all, especially diabetics
NCT ID NCT04475380
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how well the Xience Sierra drug-coated stent works in a broad group of heart disease patients, including those with diabetes or prediabetes. Over 1,700 participants received the stent during a routine procedure to open blocked arteries. Researchers tracked heart-related events like death, heart attack, or need for repeat procedures for up to two years to see if the stent is safe and effective in real-world, high-risk patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Xience Sierra everolimus-eluting stent
- What this could lead to
- If successful, this could confirm that the Xience Sierra stent is safe and effective for a wide range of heart disease patients, including those with diabetes.
- What could go wrong
- This is a completed observational study, not a randomized trial, so results may not prove superiority over other stents. Risks include typical stent complications like blood clots or re-narrowing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Haga Ziekenhuis
The Hague, Netherlands
-
Thoraxcentrum Twente
Enschede, Netherlands
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