Computer tool helps doctors choose better heart meds after attack

NCT ID NCT05844566

Completed Knowledge-focused Sponsor: Imperial College London Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a computer-based decision support system (DSS) helps doctors start or intensify cholesterol-lowering treatments earlier in patients who have had a heart attack. Over 1,100 patients from multiple hospitals took part. The DSS provided risk estimates but did not recommend specific drugs. Researchers compared outcomes between hospitals using the DSS and those providing standard care alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Decision Support System (DSS) - a computer tool that shows risk estimates
What this could lead to: If successful, this tool could help doctors make quicker, more effective decisions about cholesterol-lowering treatments after a heart attack, potentially reducing future heart risks.
What could go wrong: This is a completed trial, but the tool only provides information—it doesn't guarantee better outcomes. Results may not apply to all hospitals or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome Coronary Disease myocardial infarction Non-ST Elevated Myocardial Infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CORONARY SYNDROME MYOCARDIAL INFARCTION

Contacts and locations

Locations

A.O.U Policlinico di Modena S.C. di Cardiologia

Modena, 41124, Italy
A.O.U. Ospedali Riuniti U.O.C. Cardiologia e UTIC

Foggia, 71122, Italy
AUSL di Bologna-Ospedale Maggiore

Bologna, 40133, Italy
AUSL-IRCCS di Reggio Emilia

Reggio Emilia, 42121, Italy
Azienda Ospedaliera Universitaria Gaetano Martino

Messina, 98125, Italy
Azienda Ospedaliera di Rilievo Nazionale (A.O.R.N.) "Sant'Anna e San Sebastiano" di Caserta

Caserta, 81100, Italy
Azienda Ospedaliero Universitaria Santa Maria della Misericordia

Udine, 33100, Italy
Calderdale Royal Hospital

Halifax, West Yorkshire, HX3 0PW, United Kingdom
Conquest Hospital

Brighton, East Sussex, TN37 7PT, United Kingdom
Freeman Hospital

Newcastle upon Tyne, Tyne and Wear, NE7 7DN, United Kingdom
Glan Glwyd Hospital

Bodelwyddan, Denbighshire, LL18 5UJ, United Kingdom
Gregorio Marañón General University Hospital

Madrid, 28007, Spain
Hammersmith Hospital

London, W2 1NY, United Kingdom
Hospital Clínico Universitario Santiago de Compostela

Santiago de Compostela, A Coruña, 15706, Spain
Hospital Clínico Universitario Virgen de la Arrixaca

El Palmar, Murcia, 30120, Spain
Hospital HM Montepríncipe

Boadilla del Monte, Madrid, 28660, Spain
Hospital Universitario Fundación Jiménez Díaz

Madrid, 28040, Spain
Hospital Universitario La Luz Quiron

Madrid, 28003, Spain
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario Reina Sofia

Córdoba, 14004, Spain
Hospital Universitario Rey Juan Carlos

Móstoles, Madrid, 28933, Spain
Hospital Universitario Virgen Macarena

Seville, 41009, Spain
Hospital de la Santa Creu i Sant Pau

Barcelona, 08025, Spain
IRCCS Policlinico San Donato

Milan, 20097, Italy
IRCCS. A.O.U. Policlinico San Martino IST

Genova, 16132, Italy
Kettering General Hospital

Kettering, Northamptonshire, NN16 8UZ, United Kingdom
Luton and Dunstable University Hospital

Luton, Bedfordshire, LU4 0DZ, United Kingdom
North Tyneside General Hospital

North Shields, Tyne and Wear, NE29 8NH, United Kingdom
Ospedale Sandro Pertini - ASL Roma 2

Roma, 00157, Italy
Ospedale di Cisanello - A.U.O.P. Azienda Ospedaliera Universitaria

Pisa, 56124, Italy
Puerta de Hierro Majadahonda University Hospital

Madrid, 28222, Spain
Royal Bournemouth Hospital

Bournemouth, Dorset, BH7 7DW, United Kingdom
Royal United Hospital

Bath, Somerset, BA1 3NG, United Kingdom
Russell's Hall Hospital

Dudley, West Midlands, DY12HQ, United Kingdom
Sandwell General Hospital

Birmingham, West Midlands, B71 4HJ, United Kingdom
Scunthorpe General Hospital

Scunthorpe, North Lincolnshire, DN15 7BH, United Kingdom
Southern Health and Social Care Trust, Craigavon Area Hospital

Portadown, Northen Ireland, BT63 5QQ, United Kingdom
Sunderland Royal Hospital

Sunderland, Tyne and Wear, SR4 7TP, United Kingdom
University Hospital of A Coruña

A Coruña, Coruña, 15006, Spain
Vall d'Hebron University Hospital

Barcelona, 08035, Spain
Worcestershire Royal Hospital

Worcester, Worcestershire, WR5 1DD, United Kingdom
Worthing Hospital

Worthing, West Sussex, BN11 2DH, United Kingdom

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