Imperial College London

This study tests if a newer pacing method (physiological pacing) is better than the standard approach for people with a slow heart rate. About 2,600 adults who need a pacemaker will be randomly assigned to one of the two methods. The main goals are to see if the newer method lowe…

This study explores whether a low, non-hallucinogenic dose of psilocybin (the active ingredient in magic mushrooms) can boost a mental imagery therapy called Imagery Re-Scripting (ImRS) for young people aged 16-25 who self-harm. The goal is to see if the combination helps reduce …

This study looks at how the immune system reacts to the flu in two different ways: getting a nasal spray vaccine or being exposed to a controlled dose of live flu virus. Researchers want to understand the differences in symptoms and immune responses between vaccination and actual…

This study looks at how the body processes high doses of the steroid prednisolone in people with inflammatory diseases like thyroid eye disease, asthma, and vasculitis. Researchers will measure drug levels in the blood over time to compare short-term and long-term use. The goal i…