Scientists track prednisolone levels to improve dosing for inflammatory conditions

NCT ID NCT05012033

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is measuring prednisolone levels in 120 people with inflammatory diseases like thyroid eye disease, vasculitis, COPD, asthma, and others. Participants take high-dose prednisolone as part of their routine care, and researchers take timed blood samples to see how the drug behaves in acute versus long-term use. The goal is to better understand differences in drug processing and metabolism, which could help guide safer and more effective dosing in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
prednisolone
What this could lead to
If successful, this study could help doctors better dose prednisolone for inflammatory conditions, potentially improving treatment safety and effectiveness.
What could go wrong
This is a small, early-stage observational study, not a treatment trial. It may not lead to any changes in clinical practice, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Imperial College Healthcare NHS Trust

    RECRUITING

    London, United Kingdom

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