VASCULITIS

This study is testing a drug called avacopan in children aged 6 to 18 who have a rare autoimmune condition called ANCA-associated vasculitis. The main goal is to see if adding avacopan to standard treatments helps children achieve and maintain disease remission over one year. Res…

This study aims to see if providing doctors with a medication review tool and giving patients educational brochies can help safely reduce the number of potentially harmful or unnecessary medications taken by older adults with rheumatic diseases. It will involve about 100 particip…

This study is testing whether a new artificial intelligence (AI) tool can help doctors more completely diagnose the many complications that can occur with rheumatoid arthritis (RA), such as lung, heart, or thyroid problems. Researchers will give doctors AI-generated predictions a…

This study aims to understand how relapsing polychondritis (RP), a rare disease that causes painful inflammation of cartilage, develops and changes over time. Researchers will follow 100 people diagnosed with RP, collecting health information, blood, and urine samples every 6 to …

This study aims to understand how different types of vasculitis affect pregnancy experiences and outcomes. Researchers are inviting pregnant women with various vasculitis conditions to complete online surveys during their second trimester, third trimester, and after delivery. The…

This study aims to create a long-term collection of biological samples to help researchers better understand heart and blood vessel diseases. It will collect blood, urine, and stool samples from 500 adults who have or are at risk for these conditions. The goal is to build a share…

This study is testing a special type of MRI scan to see if it can help doctors predict which patients with kidney disease are most likely to develop serious heart problems. Researchers will scan the hearts and kidneys of 120 people with different kidney conditions, including rece…

This study aims to build a detailed picture of a rare and serious brain disease called central nervous system vasculitis (CNSV). Researchers will follow 40 adult patients for three years, collecting health information and blood samples regularly. The goal is to better understand …

This study aims to create a large collection of blood samples and health information from people with autoimmune diseases like lupus and scleroderma. Researchers will use these samples to look for new biological markers that could help diagnose diseases earlier, predict how they …

This study aims to better understand vasculitis, a group of diseases that cause blood vessel inflammation, by observing patients over time. Researchers will track 670 adults with active vasculitis to see how the disease presents, what treatments are used, and how patients fare. T…

This study aims to learn more about how different types of vasculitis affect the skin. Researchers will collect small skin samples (biopsies) from people who have active skin lesions caused by their vasculitis. By analyzing these samples, they hope to better describe and understa…