VASCULITIS

This study tests whether adding the drug avacopan to standard treatments (rituximab or cyclophosphamide) can help children aged 6 to 17 with active ANCA-associated vasculitis (AAV) achieve remission. AAV is a rare disease where the immune system attacks small blood vessels, causi…

This study looks at whether generative AI can help doctors better diagnose complications of rheumatoid arthritis (RA), such as lung disease or heart problems. Researchers will use AI to analyze patient records and suggest possible complications, then see if doctors find these sug…

This study looks at skin samples from 50 people with different types of vasculitis, a condition where blood vessels become inflamed. Researchers want to understand how the disease affects skin tissue at a molecular level. Participants must have an active skin lesion and a confirm…

This study follows women with vasculitis (inflammation of blood vessels) who become pregnant. Researchers use online surveys to track disease activity and pregnancy outcomes across each trimester. The goal is to better understand how vasculitis affects pregnancy and what unique c…

This study is following 300 people with suspected or confirmed systemic vasculitis over 10 years. Researchers are collecting data on symptoms, imaging, and biomarkers to identify who is at higher risk for relapse or poor outcomes. The goal is to better understand the disease and …

This study is testing whether a special type of MRI scan, called manganese-enhanced MRI (MEMRI), can help predict heart and kidney complications in people with kidney disease. Researchers will scan 120 adults with conditions like acute kidney injury, chronic kidney disease, or ki…

This study collects blood, urine, and stool samples from 500 adults with or at risk for heart and blood vessel diseases. The samples are stored in a biobank for future research on inflammation, metabolism, and other disease pathways. No treatments or interventions are given; the …

This study follows 40 adults with central nervous system vasculitis (CNSV), a rare and serious condition where blood vessels in the brain become inflamed, potentially causing strokes, memory loss, or dementia. Researchers will collect medical history and survey responses to learn…

This study follows 670 adults with vasculitis, a rare blood vessel disease, to see how the disease shows up, how it is treated, and what health problems may arise. Participants will be tracked during active disease or relapse, and doctors will use standard treatments. The goal is…

This study follows 100 people with relapsing polychondritis, a rare disease that causes repeated inflammation of cartilage in the ears, nose, and airways. Researchers will collect medical history and survey symptoms like fatigue and pain to better understand how the disease devel…

This study looks at whether a special tool for doctors and easy-to-read brochures for patients can help reduce the use of potentially harmful medications in adults aged 60 and older with rheumatic conditions like arthritis or lupus. Researchers will follow 100 participants for ab…

This study looks at how the body processes high doses of the steroid prednisolone in people with inflammatory diseases like thyroid eye disease, asthma, and vasculitis. Researchers will measure drug levels in the blood over time to compare short-term and long-term use. The goal i…

This study aims to create a large collection of blood and tissue samples from people with autoimmune diseases like lupus and scleroderma. Researchers will use these samples to learn more about how these diseases work, identify markers for diagnosis, and discover clues for future …