INFLAMMATORY DISEASE

This study is testing a comprehensive treatment plan for a specific, fast-worsening type of coronary artery disease believed to be driven by inflammation. It will enroll about 39 patients who have this condition. Researchers will compare each patient's health outcomes before and …

This study is testing a personalized approach for people with severe, hard-to-classify inflammatory diseases that affect multiple organs and have not responded to standard treatments. Researchers will analyze each patient's unique molecular pathways to select a targeted therapy f…

This study is testing a new type of medical scan to see if it can better detect and monitor a wide range of chronic inflammatory and scarring diseases. Researchers will use a special imaging agent in a PET/CT scan on 390 adults with conditions like rheumatoid arthritis, lupus, an…

This study aims to better understand a specific type of coronary artery disease (CAD) that is linked to chronic inflammation, often affects younger women, and doesn't respond well to standard heart treatments. Researchers will observe 120 patients with this condition over two yea…

This study aims to learn more about rare and poorly understood diseases that affect the heart and blood vessels. Researchers will enroll up to 5,000 people, including patients, their relatives, and healthy volunteers, to collect medical data, images, and samples. The goal is to i…

This study aims to understand how a person's genes affect their body's natural ability to stop inflammation. Researchers will analyze blood samples and health records from 200 volunteers of South Asian descent who are already part of a larger genetics program. The goal is to see …

This study aims to better understand a specific, fast-progressing type of heart disease linked to inflammation. Researchers will compare 20 patients with this inflammation-linked disease to 10 patients with the more common type of heart disease. They will look at medical historie…

This study aims to discover the unknown genetic causes behind rare autoinflammatory diseases, where patients experience recurring fevers and inflammation. Researchers will analyze genes and blood samples from 300 patients to identify disease patterns and pathways. The goal is to …

This study is testing whether genetic information can help doctors choose safer and more effective medications for their patients. Researchers will collect DNA samples from 1,200 adults receiving routine care at the University of Chicago Medical Center. They will track whether do…