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Massive global effort to understand inherited high cholesterol

NCT ID NCT04272697

Recruiting now Knowledge-focused Sponsor: Imperial College London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is building a large global database of people with familial hypercholesterolemia (FH), a genetic condition causing very high cholesterol and early heart disease. Researchers will analyze data from over 60,000 participants across nearly 60 countries to better understand how FH is diagnosed and treated. The goal is to improve clinical guidelines and health policies worldwide.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this registry could lead to better global guidelines for diagnosing and treating familial hypercholesterolemia, potentially reducing heart disease in affected people.
What could go wrong
This is an observational study, not a treatment trial. It collects existing data, so it cannot directly prove what works best. Results depend on the quality of data from many different countries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

familial hypercholesterolemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FAMILIAL HYPERCHOLESTEROLEMIA

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • School of Public Health, Imperial College London

    RECRUITING

    London, W6 8RP, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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